Objective: To describe proximal occlusion of a hydrosalpinx by hysteroscopic placement of a microinsert before IVF- ET. Design: Case report. Setting: Health maintenance organization and tertiary- care assisted reprodu...Objective: To describe proximal occlusion of a hydrosalpinx by hysteroscopic placement of a microinsert before IVF- ET. Design: Case report. Setting: Health maintenance organization and tertiary- care assisted reproductive technology unit. Patient(s): Obese, infertile woman with pelvic adhesive disease and unilateral hydrosalpinx. Intervention(s): Hysteroscopic placement of a microinsert into the proximal segment of a fallopian tube that was distally obstructed by hydrosalpinx. No intraoperative or postoperative complications occurred with hysteroscopic placement of microinsert. Main Outcome Mea- sure(s): Nonincisional proximal tubal occlusion under local anesthesia and intravenous sedation. Pregnancy by IVF- ET. Result(s): No intraoperative or postoperative complications with hysteroscopic placement of microinsert were seen. After uterine transfer of three embryos, dichorionic- diamniotic twins were delivered by cesarean section at 34 weeks of gestation. Conclusions(s): Hysteroscopic placement of a microinsert to proximally occlude a hydrosalpinx might be an alternative to laparoscopic proximal tubal occlusion or salpingectomy in patients with tubal disease planning IVF- ET.展开更多
目的:系统评价宫腹腔镜术结合中医疗法对输卵管阻塞性不孕症的临床疗效。方法:计算机检索中国生物医学文献数据库、中国知网、维普数据库、万方数据库、Pub Med、Embase、Web of Science、Cochrane Library等中英文数据库及中国临床试...目的:系统评价宫腹腔镜术结合中医疗法对输卵管阻塞性不孕症的临床疗效。方法:计算机检索中国生物医学文献数据库、中国知网、维普数据库、万方数据库、Pub Med、Embase、Web of Science、Cochrane Library等中英文数据库及中国临床试验注册中心和Clinical Trials。经过文献筛选临床随机对照试验(Randomized Controlled Trial,RCT)并进行治疗评价后提取有效数据,基于Rev Man 5.3软件进行Meta分析。结果:29篇文献被纳入,共计2588例患者。Meta分析结果表明,宫腹腔镜术结合中医疗法组与宫腹腔镜术组的宫内妊娠率的比较,差异有统计学意义[相对危险度(RR)95%置信区间(CI)=1.77(1.63,1.92),P<0.001];两组输卵管通畅率比较,差异有统计学意义[RR(95%CI)=1.38(1.20,1.58),P<0.001];两组总有效率相比,差异显著[RR(95%CI)=1.25(1.18,1.33),P<0.001];两组异位妊娠率相比,亦具有显著性差异[RR(95%CI)=0.51(0.35,0.75),P<0.001]。在中医外治亚组、中医内治亚组、中医内外疗法治疗亚组,两组输卵管通畅率的比较,在统计学上均表现有显著性差异:[RR=1.62(1.16,2.27),P<0.01],[RR=1.24(1.06,1.44),P<0.01],[RR=1.59(1.13,2.23),P<0.01]。所有纳入文献中仅有1篇对患者医治过程的不良反应进行了描述。结论:与宫腹腔镜术治疗相比,宫腹腔镜术结合中医疗法可以提高输卵管阻塞性不孕症患者在治疗后的宫内妊娠率、输卵管通畅率及总有效率,降低异位妊娠率,不良反应较少,有效性和安全性较高。展开更多
文摘Objective: To describe proximal occlusion of a hydrosalpinx by hysteroscopic placement of a microinsert before IVF- ET. Design: Case report. Setting: Health maintenance organization and tertiary- care assisted reproductive technology unit. Patient(s): Obese, infertile woman with pelvic adhesive disease and unilateral hydrosalpinx. Intervention(s): Hysteroscopic placement of a microinsert into the proximal segment of a fallopian tube that was distally obstructed by hydrosalpinx. No intraoperative or postoperative complications occurred with hysteroscopic placement of microinsert. Main Outcome Mea- sure(s): Nonincisional proximal tubal occlusion under local anesthesia and intravenous sedation. Pregnancy by IVF- ET. Result(s): No intraoperative or postoperative complications with hysteroscopic placement of microinsert were seen. After uterine transfer of three embryos, dichorionic- diamniotic twins were delivered by cesarean section at 34 weeks of gestation. Conclusions(s): Hysteroscopic placement of a microinsert to proximally occlude a hydrosalpinx might be an alternative to laparoscopic proximal tubal occlusion or salpingectomy in patients with tubal disease planning IVF- ET.
文摘目的:系统评价宫腹腔镜术结合中医疗法对输卵管阻塞性不孕症的临床疗效。方法:计算机检索中国生物医学文献数据库、中国知网、维普数据库、万方数据库、Pub Med、Embase、Web of Science、Cochrane Library等中英文数据库及中国临床试验注册中心和Clinical Trials。经过文献筛选临床随机对照试验(Randomized Controlled Trial,RCT)并进行治疗评价后提取有效数据,基于Rev Man 5.3软件进行Meta分析。结果:29篇文献被纳入,共计2588例患者。Meta分析结果表明,宫腹腔镜术结合中医疗法组与宫腹腔镜术组的宫内妊娠率的比较,差异有统计学意义[相对危险度(RR)95%置信区间(CI)=1.77(1.63,1.92),P<0.001];两组输卵管通畅率比较,差异有统计学意义[RR(95%CI)=1.38(1.20,1.58),P<0.001];两组总有效率相比,差异显著[RR(95%CI)=1.25(1.18,1.33),P<0.001];两组异位妊娠率相比,亦具有显著性差异[RR(95%CI)=0.51(0.35,0.75),P<0.001]。在中医外治亚组、中医内治亚组、中医内外疗法治疗亚组,两组输卵管通畅率的比较,在统计学上均表现有显著性差异:[RR=1.62(1.16,2.27),P<0.01],[RR=1.24(1.06,1.44),P<0.01],[RR=1.59(1.13,2.23),P<0.01]。所有纳入文献中仅有1篇对患者医治过程的不良反应进行了描述。结论:与宫腹腔镜术治疗相比,宫腹腔镜术结合中医疗法可以提高输卵管阻塞性不孕症患者在治疗后的宫内妊娠率、输卵管通畅率及总有效率,降低异位妊娠率,不良反应较少,有效性和安全性较高。