Both grain yield and disease performance are important factors to consider for winter wheat （Triticum aestivum） cultivar selection. However, disease index and yield data are often presented separately, making it dif...Both grain yield and disease performance are important factors to consider for winter wheat （Triticum aestivum） cultivar selection. However, disease index and yield data are often presented separately, making it difficult to compare values across multiple environments. Two-year investigations （2009-2010）, in which eight common wheat lines/genotypes were included to test their susceptibility against wheat LR （leaf rust） Puccinia triticina f. sp. tritici Roberge ex Desm., and the SLB （SeptoriaJStagonospora leaf blotch） complex Septoria tritici Desm. and Stagonospora nodorum, were carried out in the experimental field of ATTC （Agriculture Technology Transfer Centre） of Lushnje （Albania）. The objective of this study was to use a rank-based method to compare cultivars based on yield and disease performance combined across multiple environments. Analysis of variance revealed the presence of an important and significant variability in the experimental materials used to evaluate the susceptibility and the resistance of common wheat lines against SLB and LR. There were high negative correlations between yieldS, tritici （0.6683） and yield--P, recondita f. sp. tritici （0.5261）. The negative effects of two pathogens have shown ＂the parallel＂/similar negative influences on yield trait and there was a high positive correlation （0.7631） between S. tritici and P. recondita f. sp. tritici. According to study results the lines Regina × L-776, IKB-P6 and Bullgar 3 × KB 703 have shown good results of resistance （R） level against S. tritici and P. recondita f. sp. tritici.展开更多
In this paper,we show that the McKay quiver of a finite subgroup of a general linear group is a regular covering of the McKay quiver of its intersection with the special linear group.Using this and our results on &quo...In this paper,we show that the McKay quiver of a finite subgroup of a general linear group is a regular covering of the McKay quiver of its intersection with the special linear group.Using this and our results on "returning arrows" in McKay quiver,we give an algorithm to construct the McKay quiver of a finite abelian group.Using this construction,we show how the cone and cylinder of an(n-1)-Auslander absolute n-complete algebra are truncated from the McKay quivers of abelian groups.展开更多
OBJECTIVE:To study the efficacy and safety of combined Traditional Chinese Medicine(TCM) therapy based on nourishing marrow to improve intellect and reinforcing Qi to activate bloodon mild to moderate Alzheimer's ...OBJECTIVE:To study the efficacy and safety of combined Traditional Chinese Medicine(TCM) therapy based on nourishing marrow to improve intellect and reinforcing Qi to activate bloodon mild to moderate Alzheimer's disease(AD).METHODS:Sixty-six patients with AD,whoseMini-Mental State Examination(MMSE) score were from 10-24,were randomized equally into an intervention group and a control group.The control group was given Aricept(5 mg,once daily).The intervention group was further divided into Yang-Qi deficiency(n = 18) and of Yin-Qi deficiency(n = 15)subgroups.Patients in the Yang-Qi deficiency group were intravenously administered Shenfu injection,60 mL,and deproteinized calf blood injection(DCBl),1.2 g,once daily.The Yin-Qi deficiency group was given Shenmai injection,60 mL,and DCBl,1.2 g,once daily.Each course lasted 21 days.RESULTS:Compared with the control group and with pre-treatment in the same group,MMSE,clinical dementia rating,and activities of daily living scale scores in the intervention group were significantly improved(all P<0.05).These metrics mildly improved in the control group compared with before treatment(P>0.05).No adverse effects were observed in any group during treatment.CONCLUSION:We found that combined TCM therapy is effective and safe for managing mild to moderate AD.展开更多
Objective To investigate whether grain-sized moxibustion at Xinshu(BL15)and Shenshu(BL23)can alleviate cognitive decline and other pathologic features in early-stage Alzheimer disease(AD)using transgenic mice with 5 f...Objective To investigate whether grain-sized moxibustion at Xinshu(BL15)and Shenshu(BL23)can alleviate cognitive decline and other pathologic features in early-stage Alzheimer disease(AD)using transgenic mice with 5 familial AD mutations(5XFAD).Methods The genotype of transgenic mice was detected by polymerase chain reaction.A total of 40 transgenic mice(1.5 months old)were randomly and equally allocated to an AD model group(5XFAD group)or a grain-sized moxibustion group(5XFAD+GM group),with 20 wild-type(WT)mice(C57BL/6J)serving as the normal control group(WT group).Mice in the 5XFAD+GM group were treated by grain-sized moxibustion at bilateral Xinshu(BL15)and Shenshu(BL23).Mice in the WT group and 5XFAD group received no treatment but were restrained to ensure exposure to a similar experimental condition.Cognitive function and memory were assessed with the Morris water maze and Y-maze tests.The amyloidβ40(Aβ40)and amyloidβ42(Aβ42)levels in the brain were evaluated by enzyme-linked immunosorbent assay;amyloid plaque deposition in brain tissue sections was detected by thioflavin-S staining;the expression of glial fibrillary acidic protein(GFAP),cluster of differentiation 11b(CD11b),brain-derived neurotrophic factor(BDNF),and choline acetyltransferase(ChAT)in the hippocampus and prefrontal cortex was analyzed by immunohistochemistry.Results In the Morris water maze test,compared with the 5XFAD group,mice in the 5XFAD+GM group had a shorter escape latency and more target area crossings and spent more time in the target quadrant(P<0.05).In the Y-maze test,compared with the 5XFAD group,the number of training times of the 5XFAD+GM group was significantly decreased(P<0.05),together with more correct responses(P<0.05).Compared with the 5XFAD group,the levels of Aβ40 and Aβ42 in the brain tissue of the 5XFAD+GM group were significantly lower(P<0.05);in the hippocampus and prefrontal cortex,the total number of amyloidβplaque deposition were significantly lower(P<0.05);the expression levels of GFAP and CD11b were significantly reduced(P<0.05);and the expression levels of ChAT and BDNF were significantly increased(P<0.05).Conclusion Grain-sized moxibustion at Xinshu(BL15)and Shenshu(BL23)greatly improves learning and memory functions,decreases the levels of Aβ40 and Aβ42,inhibits amyloidβplaque deposition,decreases the expression of GFAP and CD11b,and increases the expression of ChAT and BDNF in AD mice to inhibit the progression of AD.展开更多
文摘Both grain yield and disease performance are important factors to consider for winter wheat （Triticum aestivum） cultivar selection. However, disease index and yield data are often presented separately, making it difficult to compare values across multiple environments. Two-year investigations （2009-2010）, in which eight common wheat lines/genotypes were included to test their susceptibility against wheat LR （leaf rust） Puccinia triticina f. sp. tritici Roberge ex Desm., and the SLB （SeptoriaJStagonospora leaf blotch） complex Septoria tritici Desm. and Stagonospora nodorum, were carried out in the experimental field of ATTC （Agriculture Technology Transfer Centre） of Lushnje （Albania）. The objective of this study was to use a rank-based method to compare cultivars based on yield and disease performance combined across multiple environments. Analysis of variance revealed the presence of an important and significant variability in the experimental materials used to evaluate the susceptibility and the resistance of common wheat lines against SLB and LR. There were high negative correlations between yieldS, tritici （0.6683） and yield--P, recondita f. sp. tritici （0.5261）. The negative effects of two pathogens have shown ＂the parallel＂/similar negative influences on yield trait and there was a high positive correlation （0.7631） between S. tritici and P. recondita f. sp. tritici. According to study results the lines Regina × L-776, IKB-P6 and Bullgar 3 × KB 703 have shown good results of resistance （R） level against S. tritici and P. recondita f. sp. tritici.
基金supported by National Natural Science Foundation of China (Grant No.10971172)
文摘In this paper,we show that the McKay quiver of a finite subgroup of a general linear group is a regular covering of the McKay quiver of its intersection with the special linear group.Using this and our results on "returning arrows" in McKay quiver,we give an algorithm to construct the McKay quiver of a finite abelian group.Using this construction,we show how the cone and cylinder of an(n-1)-Auslander absolute n-complete algebra are truncated from the McKay quivers of abelian groups.
基金the Fund of Science and Technology Project of Guangdong Province(the Mechanism Study for the Therapy of Jianpiyishenfangin Treating Glucocorticoid Tolerance MyastheniaGravis,No.2011B090400118)
文摘OBJECTIVE:To study the efficacy and safety of combined Traditional Chinese Medicine(TCM) therapy based on nourishing marrow to improve intellect and reinforcing Qi to activate bloodon mild to moderate Alzheimer's disease(AD).METHODS:Sixty-six patients with AD,whoseMini-Mental State Examination(MMSE) score were from 10-24,were randomized equally into an intervention group and a control group.The control group was given Aricept(5 mg,once daily).The intervention group was further divided into Yang-Qi deficiency(n = 18) and of Yin-Qi deficiency(n = 15)subgroups.Patients in the Yang-Qi deficiency group were intravenously administered Shenfu injection,60 mL,and deproteinized calf blood injection(DCBl),1.2 g,once daily.The Yin-Qi deficiency group was given Shenmai injection,60 mL,and DCBl,1.2 g,once daily.Each course lasted 21 days.RESULTS:Compared with the control group and with pre-treatment in the same group,MMSE,clinical dementia rating,and activities of daily living scale scores in the intervention group were significantly improved(all P<0.05).These metrics mildly improved in the control group compared with before treatment(P>0.05).No adverse effects were observed in any group during treatment.CONCLUSION:We found that combined TCM therapy is effective and safe for managing mild to moderate AD.
基金This work was supported by the Natural Science Foundation of Zhejiang Province(浙江省自然科学基金,No.LY13H270002).
文摘Objective To investigate whether grain-sized moxibustion at Xinshu(BL15)and Shenshu(BL23)can alleviate cognitive decline and other pathologic features in early-stage Alzheimer disease(AD)using transgenic mice with 5 familial AD mutations(5XFAD).Methods The genotype of transgenic mice was detected by polymerase chain reaction.A total of 40 transgenic mice(1.5 months old)were randomly and equally allocated to an AD model group(5XFAD group)or a grain-sized moxibustion group(5XFAD+GM group),with 20 wild-type(WT)mice(C57BL/6J)serving as the normal control group(WT group).Mice in the 5XFAD+GM group were treated by grain-sized moxibustion at bilateral Xinshu(BL15)and Shenshu(BL23).Mice in the WT group and 5XFAD group received no treatment but were restrained to ensure exposure to a similar experimental condition.Cognitive function and memory were assessed with the Morris water maze and Y-maze tests.The amyloidβ40(Aβ40)and amyloidβ42(Aβ42)levels in the brain were evaluated by enzyme-linked immunosorbent assay;amyloid plaque deposition in brain tissue sections was detected by thioflavin-S staining;the expression of glial fibrillary acidic protein(GFAP),cluster of differentiation 11b(CD11b),brain-derived neurotrophic factor(BDNF),and choline acetyltransferase(ChAT)in the hippocampus and prefrontal cortex was analyzed by immunohistochemistry.Results In the Morris water maze test,compared with the 5XFAD group,mice in the 5XFAD+GM group had a shorter escape latency and more target area crossings and spent more time in the target quadrant(P<0.05).In the Y-maze test,compared with the 5XFAD group,the number of training times of the 5XFAD+GM group was significantly decreased(P<0.05),together with more correct responses(P<0.05).Compared with the 5XFAD group,the levels of Aβ40 and Aβ42 in the brain tissue of the 5XFAD+GM group were significantly lower(P<0.05);in the hippocampus and prefrontal cortex,the total number of amyloidβplaque deposition were significantly lower(P<0.05);the expression levels of GFAP and CD11b were significantly reduced(P<0.05);and the expression levels of ChAT and BDNF were significantly increased(P<0.05).Conclusion Grain-sized moxibustion at Xinshu(BL15)and Shenshu(BL23)greatly improves learning and memory functions,decreases the levels of Aβ40 and Aβ42,inhibits amyloidβplaque deposition,decreases the expression of GFAP and CD11b,and increases the expression of ChAT and BDNF in AD mice to inhibit the progression of AD.
