The samples of minks from several main mink farming areas were detected by the methods of counter immunoelectrophoresis(CIEP)and polymerase chain reaction (PCR)and some data about Aleutian mink disease parvovirus(ADV)...The samples of minks from several main mink farming areas were detected by the methods of counter immunoelectrophoresis(CIEP)and polymerase chain reaction (PCR)and some data about Aleutian mink disease parvovirus(ADV)infection in farmed mink was obtained. Partial VP2 genes,which include a hypervariable region, of 16 ADV strains isolated were separately amplified by PCR and sequenced. Comparison and analysis of these genes sequences and the related sequences of ADV-G,ADV-Utah1 and ADV-K that reported in the USA and European had been completed. The result shows that : firstly, the closed relationship exists between domestic ADV isolates and foreign ones,and the domestic AD maybe introduced from foreign countries. Secondly, the ADV isolates we obtained have a high genetic diversity. DL1, DL2, MS3 and MS5 may be some new types of ADV because of so obvious differences compared with foreign isolates in the genes sequences.展开更多
水貂阿留申病（Aleutian disease of mink）,又称浆细胞增多症（Plasmacytosis）,是由细小病毒科的阿留申病病毒（ADMV）引起的一种慢性传染病,导致自身免疫系统紊乱并逐渐衰竭,并发强烈的自身免疫。主要侵害网状内皮系统,其特征为浆细...水貂阿留申病（Aleutian disease of mink）,又称浆细胞增多症（Plasmacytosis）,是由细小病毒科的阿留申病病毒（ADMV）引起的一种慢性传染病,导致自身免疫系统紊乱并逐渐衰竭,并发强烈的自身免疫。主要侵害网状内皮系统,其特征为浆细胞弥漫性增生、产生多量C-球蛋白和持续性的病毒血症。展开更多
文摘The samples of minks from several main mink farming areas were detected by the methods of counter immunoelectrophoresis(CIEP)and polymerase chain reaction (PCR)and some data about Aleutian mink disease parvovirus(ADV)infection in farmed mink was obtained. Partial VP2 genes,which include a hypervariable region, of 16 ADV strains isolated were separately amplified by PCR and sequenced. Comparison and analysis of these genes sequences and the related sequences of ADV-G,ADV-Utah1 and ADV-K that reported in the USA and European had been completed. The result shows that : firstly, the closed relationship exists between domestic ADV isolates and foreign ones,and the domestic AD maybe introduced from foreign countries. Secondly, the ADV isolates we obtained have a high genetic diversity. DL1, DL2, MS3 and MS5 may be some new types of ADV because of so obvious differences compared with foreign isolates in the genes sequences.
文摘水貂阿留申病（Aleutian disease of mink）,又称浆细胞增多症（Plasmacytosis）,是由细小病毒科的阿留申病病毒（ADMV）引起的一种慢性传染病,导致自身免疫系统紊乱并逐渐衰竭,并发强烈的自身免疫。主要侵害网状内皮系统,其特征为浆细胞弥漫性增生、产生多量C-球蛋白和持续性的病毒血症。
