Finely divided silver nanoparticles were synthesized via the hydrothermal method. Arabic gum （AG） was used as both the reductant and steric stabilizer without any other surfactant. By adjusting the reaction temperat...Finely divided silver nanoparticles were synthesized via the hydrothermal method. Arabic gum （AG） was used as both the reductant and steric stabilizer without any other surfactant. By adjusting the reaction temperature, mass ratio of AG to AgNO3, and reaction time, silver nanoparticles with different morphological characteristics could be obtained. The products were characterized by UV-Vis, FTIR, TEM, SEM, and XRD measurements. It was found that temperature and AG played an important role in the synthesis of mono-disperse silver nanoparticles. Well dispersed and quasispherical silver nanoparticles were obtained under the optimal synthesis conditions of 10 mmol/L AgNO3, m（AG）/m（AgN03）= l：1, 160 ℃ and 3 h.展开更多
AIM:To investigate the appropriate time for combination therapy in HBeAg positive chronic hepatitis B(CHB) patients with decompensated cirrhosis.METHODS:Thirty HBeAg positive CHB patients with decompensated cirrhosis ...AIM:To investigate the appropriate time for combination therapy in HBeAg positive chronic hepatitis B(CHB) patients with decompensated cirrhosis.METHODS:Thirty HBeAg positive CHB patients with decompensated cirrhosis were enrolled in the study.All of the patients were given 48 wk combination therapy with lamivudine(LAM) and adefovir dipivoxil(ADV) .Briefly,10 patients were given the de novo combination therapy with LAM and ADV,whereas the other 20 patients received ADV in addition to LAM after hepatitis B virus(HBV) genetic mutation.RESULTS:Serum alanine aminotransferase and total bilirubin were both improved in the two groups at 4,12,24 and 48 wk after treatment.Serum albumin was also improved at 24 and 48 wk after combination therapy in both groups.The serum HBV DNA level wasstill detectable in every patient in the two groups at 4 and 12 wk after combination treatment.However,in the de novo combination group,serum HBV DNA levels in 4(40%) and 9(90%) patients was decreased to below 1×10 3 copies/mL at 24 and 48 wk after the combination treatment,respectively.In parallel,serum HBV DNA levels in 2(20%) and 8(40%) patients in the add-on combination group became undetectable at 24 and 48 wk after combination treatment,respectively.Furthermore,6(60%) patients in the de novo combination group achieved HBeAg seroconversion after 48 wk treatment,whereas only 4(20%) patients in the add-on combination group achieved seroconversion.Child-Pugh score of patients in the de novo combination group was better than that of patients in the add-on combination group after 48 wk treatment.Moreover,patients in the de novo combination group had a significantly decreased serum creatinine level and elevated red blood cell counts.CONCLUSION:De novo combination therapy with LAM and ADV was better than add-on combination therapy in terms of Child-Pugh score,virus inhibition and renal function.展开更多
It is argued that it has not yet been able to value the historical, philosophical and epistemological travail, represented by the filth and fourth centuries BC of the ancient Greek world, which preceded the highest sc...It is argued that it has not yet been able to value the historical, philosophical and epistemological travail, represented by the filth and fourth centuries BC of the ancient Greek world, which preceded the highest scientific heritage, represented by the so-called golden age of Euclid, Archimedes and Apollonius, Ⅲ-Ⅱ century BC. Well, it is believed that with our complex concept of tradition of thought within which we insert not only epistemological concepts but also philosophical principles, historical and social frameworks, in stasis or in strong movement, processed by us, it is possible better interpret that happy moment of scientific constructions of the third and second century BC, as a result of the valorization of the deep travail and serious battle that preceded it between the fourth and fifth century BC. It is investigated in particular in our paper the development of astronomical thought between the fifth and fourth centuries BC, in the ancient Greek thought, and at last a particular presumed criticism by Archimedes in his Sandreckoner to Aristarchus.展开更多
文摘Finely divided silver nanoparticles were synthesized via the hydrothermal method. Arabic gum （AG） was used as both the reductant and steric stabilizer without any other surfactant. By adjusting the reaction temperature, mass ratio of AG to AgNO3, and reaction time, silver nanoparticles with different morphological characteristics could be obtained. The products were characterized by UV-Vis, FTIR, TEM, SEM, and XRD measurements. It was found that temperature and AG played an important role in the synthesis of mono-disperse silver nanoparticles. Well dispersed and quasispherical silver nanoparticles were obtained under the optimal synthesis conditions of 10 mmol/L AgNO3, m（AG）/m（AgN03）= l：1, 160 ℃ and 3 h.
基金Supported by Glorious Funds from Chinese foundation for hepatitis prevention and control,No.GHF2010205
文摘AIM:To investigate the appropriate time for combination therapy in HBeAg positive chronic hepatitis B(CHB) patients with decompensated cirrhosis.METHODS:Thirty HBeAg positive CHB patients with decompensated cirrhosis were enrolled in the study.All of the patients were given 48 wk combination therapy with lamivudine(LAM) and adefovir dipivoxil(ADV) .Briefly,10 patients were given the de novo combination therapy with LAM and ADV,whereas the other 20 patients received ADV in addition to LAM after hepatitis B virus(HBV) genetic mutation.RESULTS:Serum alanine aminotransferase and total bilirubin were both improved in the two groups at 4,12,24 and 48 wk after treatment.Serum albumin was also improved at 24 and 48 wk after combination therapy in both groups.The serum HBV DNA level wasstill detectable in every patient in the two groups at 4 and 12 wk after combination treatment.However,in the de novo combination group,serum HBV DNA levels in 4(40%) and 9(90%) patients was decreased to below 1×10 3 copies/mL at 24 and 48 wk after the combination treatment,respectively.In parallel,serum HBV DNA levels in 2(20%) and 8(40%) patients in the add-on combination group became undetectable at 24 and 48 wk after combination treatment,respectively.Furthermore,6(60%) patients in the de novo combination group achieved HBeAg seroconversion after 48 wk treatment,whereas only 4(20%) patients in the add-on combination group achieved seroconversion.Child-Pugh score of patients in the de novo combination group was better than that of patients in the add-on combination group after 48 wk treatment.Moreover,patients in the de novo combination group had a significantly decreased serum creatinine level and elevated red blood cell counts.CONCLUSION:De novo combination therapy with LAM and ADV was better than add-on combination therapy in terms of Child-Pugh score,virus inhibition and renal function.
文摘It is argued that it has not yet been able to value the historical, philosophical and epistemological travail, represented by the filth and fourth centuries BC of the ancient Greek world, which preceded the highest scientific heritage, represented by the so-called golden age of Euclid, Archimedes and Apollonius, Ⅲ-Ⅱ century BC. Well, it is believed that with our complex concept of tradition of thought within which we insert not only epistemological concepts but also philosophical principles, historical and social frameworks, in stasis or in strong movement, processed by us, it is possible better interpret that happy moment of scientific constructions of the third and second century BC, as a result of the valorization of the deep travail and serious battle that preceded it between the fourth and fifth century BC. It is investigated in particular in our paper the development of astronomical thought between the fifth and fourth centuries BC, in the ancient Greek thought, and at last a particular presumed criticism by Archimedes in his Sandreckoner to Aristarchus.
