Objective To preliminarily evaluate the efficacy of the Fu Zheng method(supporting resistance against pathogenic factors)applied by Professor Hong-Feng CHEN in improving the quality of life in patients with triple-neg...Objective To preliminarily evaluate the efficacy of the Fu Zheng method(supporting resistance against pathogenic factors)applied by Professor Hong-Feng CHEN in improving the quality of life in patients with triple-negative breast cancer(TNBC)to collect and organize the traditional Chinese medicine(TCM)formulas applied by Professor Hong-Feng CHEN in the treatment of TNBC in order to explore the patterns in prescription.Methods The Functional Assessment of Cancer Therapy-Breast scale(FACT-B V4.0)were collected before and after treatment;the database and data mining platform for prescribed TCM formulas were constructed using Microsoft SQL Server 2005,and the patterns in drug pairing and combination were summarized by correlation analysis of data mining.Results The formulas improved the mean scores of the patients’physical well-being,social/family well-being,emotional well-being,physical function well-being and additional concerns(P<0.01);the drug combinations and pairs frequently used by Professor Hong-Feng CHEN were summarized.Conclusion The TCM formulas applied by Professor Hong-Feng CHEN can alleviate adverse physiological reactions,improve psychological conditions and improve function in patients.The formulas take spleen invigoration and stomach nourishment as well as blood circulation promotion and stagnation dissipation as the therapeutic principles,with simplicity in prescription and focus on care and protection the foundation of acquired constitution.展开更多
Based on the single-factor market model, this paper examines the confirmation basis and measurement of the losses arising from systematic risk in the civil damages of false statements. The paper argues that the system...Based on the single-factor market model, this paper examines the confirmation basis and measurement of the losses arising from systematic risk in the civil damages of false statements. The paper argues that the systematic risk not only affects the investment in securities during times of financial crisis, but also causes losses in daily securities trading. The paper carries out an empirical analysis on the existence of fl coefficient for China's listed companies within a period of one year, and examines the impact of systematic risk on the losses of investors. The civil damages of false statements should take full account of the losses arising from systematic risk. After analysis, the paper uses the correlation coefficient to represent the ratio of losses arising from systematic risk of all the transactions of a particular stock during a certain period of time, and tries to develop two methods to measure the damages after adjusting the losses caused by the systematic risk. The paper has a theoretical foundation for the estimation of losses caused by systematic risk, and matches the risks and returns. The result of the paper has provided an effective method of calculation in the determination of reasonable damages in the case of China Langfang Development Co., Ltd.展开更多
Early life overfeeding in the rat can be experimentally induced by reducing litter size. This investigation assessed the consequences of this manipulation on glucose metabolism in vivo and in isolated hepatocytes in 1...Early life overfeeding in the rat can be experimentally induced by reducing litter size. This investigation assessed the consequences of this manipulation on glucose metabolism in vivo and in isolated hepatocytes in 150-day old rats. Additionally, after body growth, the effects of caloric restriction and refeeding were tested. Adult rats from control (G9) and reduced litters (G3L) did not differ in body and fat weights, glucose tolerance or insulin resistance (insulin-induced hypoglycemia), or hepatocyte glucose release under basal or gluconeogenic conditions. Caloric restriction (G3R) reduced body and fat weights, decreased glucose decay after insulin injection and decreased hepatocyte gluconeogenic glucose release. Refeeding after caloric restriction reversed these parameters to those of the freely-fed groups (G9 and G3L). Taken together, these results suggest that the liver glucose metabolism is not programmed by lactational overfeeding, but rather is responsive to the current nutritional condition of the animal.展开更多
Teaching goal design is an important link of teaching design, which has the teaching, learning and measurement function. How to establish the appropriate teaching goal and properly state to enhance its guidance and de...Teaching goal design is an important link of teaching design, which has the teaching, learning and measurement function. How to establish the appropriate teaching goal and properly state to enhance its guidance and detection function are the important tasks of teaching design. This paper makes a programming and systematic analysis on the aspects of teaching goal design theory, teaching goal statement mode and technology, teaching goal statement and design and teaching goal design detection.展开更多
Crude decoction, aqueous and ethanolic extracts of two medicinal plants (Psidiura guajava and Diospyros raespiliformis), widely used in the central plateau of Burkina Faso to treat many diseases were evaluated for t...Crude decoction, aqueous and ethanolic extracts of two medicinal plants (Psidiura guajava and Diospyros raespiliformis), widely used in the central plateau of Burkina Faso to treat many diseases were evaluated for their antagonistic effects on caffeine induced calcium release from sarcoplasmic reticulum of rat skeletal muscle cells. These different extracts showed a decrease of caffeine induced calcium release in a dose dependent manner. Comparison of the results showed that Psidiura guajava leaf extracts are more active than extracts of Diospyros mespiliformis and that crude decoctions show better inhibitory activity. The observed results could explaine their use as antihypertensive and antidiarrhoeal agents in traditional medicine, by inhibiting intracellular calcium release.展开更多
Urban metabolism provides a robust framework for analyzing urban development and its impacts.However,several conceptual and operational shortcomings have constrained the application of urban metabolism in understandin...Urban metabolism provides a robust framework for analyzing urban development and its impacts.However,several conceptual and operational shortcomings have constrained the application of urban metabolism in understanding the overall urban processes,limiting the transfer of its potential benefits to design and planning.This article systematically analysed the rationale of the current urban metabolism models,focusing on four prevailing shortcomings from a transdisciplinary perspective:1)utilizing an isolated state approach,which treats urban systems as isolated from other ecosystems;2)ignoring internal processes within urban systems,known as the black box paradox;3)employing a linear material approach that focuses on the path of single materials;and 4)overlooking the material productivity of urban systems,where energy and materials entering the system are used to reproduce the urban material structure and generate goods and tradable products.While these issues have been identified individually in existing scientific literature,there is a lack of holistic solutions.This article proposes an enhanced urban metabolism analytical approachDthe ecosystem approach applying atechnomassoDto address these shortcomings and provide practical solutions in landscape architecture and planning disciplines for sustainable urban development.展开更多
In this paper, the Kahler conditions of the Chern-Finsler connection in complex Finsler geometry are studied, and it is proved that Kahler Finsler metrics are actually strongly Kahler.
In this paper, the Laplacian on the holomorphic tangent bundle T 1,0 M of a complex manifold M endowed with a strongly pseudoconvex complex Finsler metric is defined and its explicit expression is obtained by using th...In this paper, the Laplacian on the holomorphic tangent bundle T 1,0 M of a complex manifold M endowed with a strongly pseudoconvex complex Finsler metric is defined and its explicit expression is obtained by using the Chern Finsler connection associated with (M, F ). Utilizing the initiated "Bochner technique", a vanishing theorem for vector fields on the holomorphic tangent bundle T 1,0 M is obtained.展开更多
Postmenopausal women, who have reduced circulating estrogen levels, are more prone to develop obesity and related metabolic diseases than premenopausal women. The absence of safe and effective treatments for postmenop...Postmenopausal women, who have reduced circulating estrogen levels, are more prone to develop obesity and related metabolic diseases than premenopausal women. The absence of safe and effective treatments for postmenopausal obesity has changed the focus to natural products as alternative remedies. Total salvianolic acids(TSA) are the major water-soluble ingredients of Danshen. Salvianolic acid(SA) is the major constituent of the TSA. Salvianolic acids, including TSA and SA, are widely used in traditional Chinese medicine. In the present study, ovariectomized rats and LO2 cells were used to study the effects of salvianolic acids on body weight gain and hepatic steatosis. Salvianolic acids reduced ovariectomy(OVX)-induced body weight gain, attenuated the expressions of hepatic lipogenic genes, such as sterol regulatory element binding protein(SREBP)1, fatty acid synthase(FAS), and stearoyl-CoA desaturase(SCD)1, and decreased the liver triglyceride(TG) and total cholesterol(TC). For the molecular mechanisms, OVX and high glucose-induced phosphorylation of signal transducer and activator of transcription(STAT)-3 was inhibited by salvianolic acids treatment. In LO2 cells, inhibition of STAT-3 by siRNA attenuated the increased expression of SREBP1 and TG induced by high glucose. Salvianolic acids reduced the upregulation of SREBP1 and TG induced by high glucose in LO2 cells. In conclusion, these findings illustrated that salvianolic acids markedly alleviated the lipid metabolism disorders and protected against the postmenopausal obesity. The underlying mechanism was probably associated with the regulation of STAT-3 signaling.展开更多
This is a contribution to the project of quiver approaches to quasi-quantum groups.We classify Majid bimodules over groups with 3-cocycles by virtue of projective representations.This leads to a theoretic classificati...This is a contribution to the project of quiver approaches to quasi-quantum groups.We classify Majid bimodules over groups with 3-cocycles by virtue of projective representations.This leads to a theoretic classification of graded pointed Majid algebras over path coalgebras,or equivalently cofree pointed coalgebras,and helps to provide a projective representation-theoretic description of the gauge equivalence of graded pointed Majid algebras.We apply this machinery to construct some concrete examples and obtain a classification of finite-dimensional graded pointed Majid algebras with the set of group-likes equal to the cyclic group of order 2.展开更多
We show that the quantum-mechanical fundamental representations, say, the coordinate representation, the coherent state representation, the Fan-Klauder entangled state representation can be recast into s-ordering oper...We show that the quantum-mechanical fundamental representations, say, the coordinate representation, the coherent state representation, the Fan-Klauder entangled state representation can be recast into s-ordering operator expansion, which is elegant in form and has many applications in deriving new operator identities. This demonstrates that Dirac's symbolic method can be merged into Newton-Leibniz integration theory in a broad way.展开更多
基金support from the Shanghai TCM Gushi Surgical School Heritage Research Base Construction Project of Shanghai Health Bureau(ZYSNXD-CC-APGC-JD-002)
文摘Objective To preliminarily evaluate the efficacy of the Fu Zheng method(supporting resistance against pathogenic factors)applied by Professor Hong-Feng CHEN in improving the quality of life in patients with triple-negative breast cancer(TNBC)to collect and organize the traditional Chinese medicine(TCM)formulas applied by Professor Hong-Feng CHEN in the treatment of TNBC in order to explore the patterns in prescription.Methods The Functional Assessment of Cancer Therapy-Breast scale(FACT-B V4.0)were collected before and after treatment;the database and data mining platform for prescribed TCM formulas were constructed using Microsoft SQL Server 2005,and the patterns in drug pairing and combination were summarized by correlation analysis of data mining.Results The formulas improved the mean scores of the patients’physical well-being,social/family well-being,emotional well-being,physical function well-being and additional concerns(P<0.01);the drug combinations and pairs frequently used by Professor Hong-Feng CHEN were summarized.Conclusion The TCM formulas applied by Professor Hong-Feng CHEN can alleviate adverse physiological reactions,improve psychological conditions and improve function in patients.The formulas take spleen invigoration and stomach nourishment as well as blood circulation promotion and stagnation dissipation as the therapeutic principles,with simplicity in prescription and focus on care and protection the foundation of acquired constitution.
文摘Based on the single-factor market model, this paper examines the confirmation basis and measurement of the losses arising from systematic risk in the civil damages of false statements. The paper argues that the systematic risk not only affects the investment in securities during times of financial crisis, but also causes losses in daily securities trading. The paper carries out an empirical analysis on the existence of fl coefficient for China's listed companies within a period of one year, and examines the impact of systematic risk on the losses of investors. The civil damages of false statements should take full account of the losses arising from systematic risk. After analysis, the paper uses the correlation coefficient to represent the ratio of losses arising from systematic risk of all the transactions of a particular stock during a certain period of time, and tries to develop two methods to measure the damages after adjusting the losses caused by the systematic risk. The paper has a theoretical foundation for the estimation of losses caused by systematic risk, and matches the risks and returns. The result of the paper has provided an effective method of calculation in the determination of reasonable damages in the case of China Langfang Development Co., Ltd.
文摘Early life overfeeding in the rat can be experimentally induced by reducing litter size. This investigation assessed the consequences of this manipulation on glucose metabolism in vivo and in isolated hepatocytes in 150-day old rats. Additionally, after body growth, the effects of caloric restriction and refeeding were tested. Adult rats from control (G9) and reduced litters (G3L) did not differ in body and fat weights, glucose tolerance or insulin resistance (insulin-induced hypoglycemia), or hepatocyte glucose release under basal or gluconeogenic conditions. Caloric restriction (G3R) reduced body and fat weights, decreased glucose decay after insulin injection and decreased hepatocyte gluconeogenic glucose release. Refeeding after caloric restriction reversed these parameters to those of the freely-fed groups (G9 and G3L). Taken together, these results suggest that the liver glucose metabolism is not programmed by lactational overfeeding, but rather is responsive to the current nutritional condition of the animal.
文摘Teaching goal design is an important link of teaching design, which has the teaching, learning and measurement function. How to establish the appropriate teaching goal and properly state to enhance its guidance and detection function are the important tasks of teaching design. This paper makes a programming and systematic analysis on the aspects of teaching goal design theory, teaching goal statement mode and technology, teaching goal statement and design and teaching goal design detection.
文摘Crude decoction, aqueous and ethanolic extracts of two medicinal plants (Psidiura guajava and Diospyros raespiliformis), widely used in the central plateau of Burkina Faso to treat many diseases were evaluated for their antagonistic effects on caffeine induced calcium release from sarcoplasmic reticulum of rat skeletal muscle cells. These different extracts showed a decrease of caffeine induced calcium release in a dose dependent manner. Comparison of the results showed that Psidiura guajava leaf extracts are more active than extracts of Diospyros mespiliformis and that crude decoctions show better inhibitory activity. The observed results could explaine their use as antihypertensive and antidiarrhoeal agents in traditional medicine, by inhibiting intracellular calcium release.
文摘Urban metabolism provides a robust framework for analyzing urban development and its impacts.However,several conceptual and operational shortcomings have constrained the application of urban metabolism in understanding the overall urban processes,limiting the transfer of its potential benefits to design and planning.This article systematically analysed the rationale of the current urban metabolism models,focusing on four prevailing shortcomings from a transdisciplinary perspective:1)utilizing an isolated state approach,which treats urban systems as isolated from other ecosystems;2)ignoring internal processes within urban systems,known as the black box paradox;3)employing a linear material approach that focuses on the path of single materials;and 4)overlooking the material productivity of urban systems,where energy and materials entering the system are used to reproduce the urban material structure and generate goods and tradable products.While these issues have been identified individually in existing scientific literature,there is a lack of holistic solutions.This article proposes an enhanced urban metabolism analytical approachDthe ecosystem approach applying atechnomassoDto address these shortcomings and provide practical solutions in landscape architecture and planning disciplines for sustainable urban development.
基金Project supported by the National Natural Science Foundation of China (No. 10571154)
文摘In this paper, the Kahler conditions of the Chern-Finsler connection in complex Finsler geometry are studied, and it is proved that Kahler Finsler metrics are actually strongly Kahler.
基金Project Supported by the National Natural Science Foundation of China (Nos. 10871145, 10771174)the Doctoral Program Foundation of the Ministry of Education of China (No. 2009007Q110053)
文摘In this paper, the Laplacian on the holomorphic tangent bundle T 1,0 M of a complex manifold M endowed with a strongly pseudoconvex complex Finsler metric is defined and its explicit expression is obtained by using the Chern Finsler connection associated with (M, F ). Utilizing the initiated "Bochner technique", a vanishing theorem for vector fields on the holomorphic tangent bundle T 1,0 M is obtained.
基金supported by National Natural Science Foundation of China(Nos.81573183 and 81673205)the Major Program of Natural Science Research of Jiangsu Higher Education Institutions(No.15KJA330001)+2 种基金the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)Gansu Provincial Natural Science Foundation(No.148RJZA081)Lanzhou Science and Technology(2014-1-18)
文摘Postmenopausal women, who have reduced circulating estrogen levels, are more prone to develop obesity and related metabolic diseases than premenopausal women. The absence of safe and effective treatments for postmenopausal obesity has changed the focus to natural products as alternative remedies. Total salvianolic acids(TSA) are the major water-soluble ingredients of Danshen. Salvianolic acid(SA) is the major constituent of the TSA. Salvianolic acids, including TSA and SA, are widely used in traditional Chinese medicine. In the present study, ovariectomized rats and LO2 cells were used to study the effects of salvianolic acids on body weight gain and hepatic steatosis. Salvianolic acids reduced ovariectomy(OVX)-induced body weight gain, attenuated the expressions of hepatic lipogenic genes, such as sterol regulatory element binding protein(SREBP)1, fatty acid synthase(FAS), and stearoyl-CoA desaturase(SCD)1, and decreased the liver triglyceride(TG) and total cholesterol(TC). For the molecular mechanisms, OVX and high glucose-induced phosphorylation of signal transducer and activator of transcription(STAT)-3 was inhibited by salvianolic acids treatment. In LO2 cells, inhibition of STAT-3 by siRNA attenuated the increased expression of SREBP1 and TG induced by high glucose. Salvianolic acids reduced the upregulation of SREBP1 and TG induced by high glucose in LO2 cells. In conclusion, these findings illustrated that salvianolic acids markedly alleviated the lipid metabolism disorders and protected against the postmenopausal obesity. The underlying mechanism was probably associated with the regulation of STAT-3 signaling.
基金supported by National Natural Science Foundation of China(Grant No. 10601052)Natural Science Foundation of Shandong Province(Grant No.2009ZRA01128)the Independent Innovation Foundation of Shandong University(Grant No.2010TS021)
文摘This is a contribution to the project of quiver approaches to quasi-quantum groups.We classify Majid bimodules over groups with 3-cocycles by virtue of projective representations.This leads to a theoretic classification of graded pointed Majid algebras over path coalgebras,or equivalently cofree pointed coalgebras,and helps to provide a projective representation-theoretic description of the gauge equivalence of graded pointed Majid algebras.We apply this machinery to construct some concrete examples and obtain a classification of finite-dimensional graded pointed Majid algebras with the set of group-likes equal to the cyclic group of order 2.
基金supported by the National Natural Science Foundation of China (Grant Nos.10775097 and 10874174)the Special Funds of the National Natural Science Foundation of China (Grant No.10947017/A05)+1 种基金the Higher School Fund of Outstanding Young Talent (Grant No.2010SQRL132)the Scientific Research Starting Foundation of Chizhou University (Grant No.2010RC036)
文摘We show that the quantum-mechanical fundamental representations, say, the coordinate representation, the coherent state representation, the Fan-Klauder entangled state representation can be recast into s-ordering operator expansion, which is elegant in form and has many applications in deriving new operator identities. This demonstrates that Dirac's symbolic method can be merged into Newton-Leibniz integration theory in a broad way.