目的研究降乳方联合溴隐亭对特发性高催乳素(prolactin,PRL)血症月经后期的疗效。方法将60例特发性高PRL血症月经后期患者随机分为治疗组(30例)和对照组(30例),治疗组给予降乳方加溴隐亭,对照组给予溴隐亭,比较两组治疗后的血清PRL、雌...目的研究降乳方联合溴隐亭对特发性高催乳素(prolactin,PRL)血症月经后期的疗效。方法将60例特发性高PRL血症月经后期患者随机分为治疗组(30例)和对照组(30例),治疗组给予降乳方加溴隐亭,对照组给予溴隐亭,比较两组治疗后的血清PRL、雌二醇(estradiol,E2)、卵泡刺激素(follicle-stimulating hormone,FSH)、黄体生成素(luteinizing hormone,LH)水平,月经积分,中医证候积分,基础体温(basal body temperature,BBT),疗效,用药不良反应及停药后复发率。结果治疗后,两组血清PRL水平均降低,E2、FSH、LH水平及BBT双向率均升高,差异有统计学意义(P<0.01);且治疗组月经积分及中医证候积分均低于对照组,差异有统计学意义(P<0.01);治疗组中医证候疗效总有效率96.67%高于对照组的80%,总体疗效的有效率96.67%高于对照组的73.33%,差异均具有统计学意义(P<0.05);治疗组不良反应发生率为6.67%,低于对照组的26.67%,且治疗组复发率为6.67%,低于对照组的37.04%,差异均具有统计学意义(P<0.05)。结论降乳方联合溴隐亭可使高PRL血症月经后期患者体内PRL水平降低,使E2、FSH、LH水平升高,使中医证候积分降低,调整月经周期,提高排卵率,提高临床疗效,用药安全性高,停药后复发率低。展开更多
The organic phase separated from the interfacial crud provided by Dexing copper mine in Jiangxi, China, was analyzed by combined gas chromatography-mass spectroscopy. The results show that many kinds of emphiphiles co...The organic phase separated from the interfacial crud provided by Dexing copper mine in Jiangxi, China, was analyzed by combined gas chromatography-mass spectroscopy. The results show that many kinds of emphiphiles containing such hydrophilic groups as carbonyl, carboxyl, sulphonyl or acylamine exist in organic phase. Conclusively, Lix984N would degrade gradually during a long-term contact with the acidic aqueous feed and strip reagents. Lix84 and nonylphenol as effective components of Lix984N degraded almost completely after long-term recycling. Lix984N degraded through such reactions as Beck.mann rearrange, hydrolysis and sulphofication. The degradation of Lix984N would deteriorate solvent extraction and disengagement performance, and result in a more stable interracial emulsion.展开更多
文摘目的研究降乳方联合溴隐亭对特发性高催乳素(prolactin,PRL)血症月经后期的疗效。方法将60例特发性高PRL血症月经后期患者随机分为治疗组(30例)和对照组(30例),治疗组给予降乳方加溴隐亭,对照组给予溴隐亭,比较两组治疗后的血清PRL、雌二醇(estradiol,E2)、卵泡刺激素(follicle-stimulating hormone,FSH)、黄体生成素(luteinizing hormone,LH)水平,月经积分,中医证候积分,基础体温(basal body temperature,BBT),疗效,用药不良反应及停药后复发率。结果治疗后,两组血清PRL水平均降低,E2、FSH、LH水平及BBT双向率均升高,差异有统计学意义(P<0.01);且治疗组月经积分及中医证候积分均低于对照组,差异有统计学意义(P<0.01);治疗组中医证候疗效总有效率96.67%高于对照组的80%,总体疗效的有效率96.67%高于对照组的73.33%,差异均具有统计学意义(P<0.05);治疗组不良反应发生率为6.67%,低于对照组的26.67%,且治疗组复发率为6.67%,低于对照组的37.04%,差异均具有统计学意义(P<0.05)。结论降乳方联合溴隐亭可使高PRL血症月经后期患者体内PRL水平降低,使E2、FSH、LH水平升高,使中医证候积分降低,调整月经周期,提高排卵率,提高临床疗效,用药安全性高,停药后复发率低。
基金Project (P1502) supported by Shanghai Leading Academic Discipline
文摘The organic phase separated from the interfacial crud provided by Dexing copper mine in Jiangxi, China, was analyzed by combined gas chromatography-mass spectroscopy. The results show that many kinds of emphiphiles containing such hydrophilic groups as carbonyl, carboxyl, sulphonyl or acylamine exist in organic phase. Conclusively, Lix984N would degrade gradually during a long-term contact with the acidic aqueous feed and strip reagents. Lix84 and nonylphenol as effective components of Lix984N degraded almost completely after long-term recycling. Lix984N degraded through such reactions as Beck.mann rearrange, hydrolysis and sulphofication. The degradation of Lix984N would deteriorate solvent extraction and disengagement performance, and result in a more stable interracial emulsion.