期刊文献+
共找到6篇文章
< 1 >
每页显示 20 50 100
兴奋大鼠延髓A_1区引起降压、降心率效应的机制 被引量:4
1
作者 魏东 顾蕴辉 《生理学报》 CAS CSCD 北大核心 1989年第5期444-451,共8页
在水合氯醛麻醉、箭毒化、人工呼吸的大鼠,观察到:(1) A_1区注入谷氨酸钠引起明显的血压下降和心率减慢。(2) 切断双侧颈迷走神经明显衰减A_1区的降压,降心率效应。(3) 延髓头端腹外侧区(RVL)预先注射酚妥拉明或心得安,均能明显衰减谷... 在水合氯醛麻醉、箭毒化、人工呼吸的大鼠,观察到:(1) A_1区注入谷氨酸钠引起明显的血压下降和心率减慢。(2) 切断双侧颈迷走神经明显衰减A_1区的降压,降心率效应。(3) 延髓头端腹外侧区(RVL)预先注射酚妥拉明或心得安,均能明显衰减谷氨酸钠兴奋A_1区的降压效应,A_1区的降心率作用基本不受影响,将纳洛酮注入RVL后,A_1区的降压和降心率效应均无明显变化;注射荷包牡丹碱入RVL则使A_1区的降压、降心率效应反转。(4) RVL内注入酚妥拉明或心得安本身使基础血压降低,注射荷包牡丹碱入RVL则使基础血压升高(提示RVL内的α-,β-受体中介对RVE加压神经元的紧张性兴奋作用,GABA受体中介紧张性抑制作用);另一方面,RVL内注入心得安使基础心率减慢、注入纳洛酮或荷包牡丹碱使基础心率加快(说明β-受体中介紧张性心加速效应,阿片受体和GABA受体中介紧张性心抑制效应)。 展开更多
关键词 延髓A1区 降心率
下载PDF
顶核-延髓头端腹外侧区系统参与前庭降压降心率反应 被引量:1
2
作者 罗萍 顾蕴辉 《生理学报》 CAS CSCD 北大核心 1992年第1期31-38,共8页
实验用乌拉坦麻醉、箭毒化、人工呼吸的大鼠。将神经元胞体兴奋剂L-谷氨酸钠(Glu)微量注入顶核或前庭上核均引起血压下降;心率减慢。该顶核-和前庭上核-降压降心率反应均可被延髓头端腹外侧区内注射GABA受体阻断剂荷包牡丹碱阻断。顶核... 实验用乌拉坦麻醉、箭毒化、人工呼吸的大鼠。将神经元胞体兴奋剂L-谷氨酸钠(Glu)微量注入顶核或前庭上核均引起血压下降;心率减慢。该顶核-和前庭上核-降压降心率反应均可被延髓头端腹外侧区内注射GABA受体阻断剂荷包牡丹碱阻断。顶核内注射普鲁卡因也能阻断Glu兴奋前庭上核的心血管反应。以上结果提示前庭-降压降心率反应可能通过顶核-延髓头端腹外侧区系统实现。静脉注射甲基阿托品也能衰减Glu兴奋顶核的心血管反应,显示迷走神经也参与前庭-顶核降压降心率反应。 展开更多
关键词 顶核 前庭上核 RVL 降心率
下载PDF
大鼠延髓A_5区降压、降心率效应的机制及其与A_1区之比较 被引量:1
3
作者 魏东 顾蕴辉 《生理学报》 CAS CSCD 北大核心 1989年第5期452-458,共7页
在与上一篇论文(关于A_1区)相同的条件下,(1) 用谷氨酸钠兴奋大鼠A_5区,和A_1区类似,也产生明显的降压、降心率效应。(2) 切断双侧颈迷走神经也明显衰减兴奋A_5区的心血管作用。(3) 将不同受体阻断剂注入延髓头端腹外侧区对兴奋A_5区引... 在与上一篇论文(关于A_1区)相同的条件下,(1) 用谷氨酸钠兴奋大鼠A_5区,和A_1区类似,也产生明显的降压、降心率效应。(2) 切断双侧颈迷走神经也明显衰减兴奋A_5区的心血管作用。(3) 将不同受体阻断剂注入延髓头端腹外侧区对兴奋A_5区引起的降压,降心率反应之影响,与A_1区比较有所不同:酚妥拉明、心得安、纳洛酮和荷包牡丹碱均能明显衰减A_5区的降压、降心率效应(心得安和荷包牡丹碱甚至反转之),表明除α-,β-,GABA受体之外,阿片受体也中介A_5区的降压降心率作用。 展开更多
关键词 延髓A5区 降心率 A1区
下载PDF
高血压患者血压、心率应双达标
4
作者 冯冯 《家庭医药(快乐养生)》 2017年第1期48-48,共1页
你知道人的寿命长短与心率之间有莫大关系吗?研究发现,在正常范围内,心率越慢,人越长寿。一只仓鼠的平均寿命在2岁左右,其心率每分钟可达500次;而能活到近200岁的乌龟,其心率每分钟却只有6次。健康的人或许能够承受短暂的怦然心动,然... 你知道人的寿命长短与心率之间有莫大关系吗?研究发现,在正常范围内,心率越慢,人越长寿。一只仓鼠的平均寿命在2岁左右,其心率每分钟可达500次;而能活到近200岁的乌龟,其心率每分钟却只有6次。健康的人或许能够承受短暂的怦然心动,然而高血压患者可就得留意自己的心率了。 展开更多
关键词 交感神经兴奋 降心率药物 Β受体阻滞剂 血管病患者 改善生活 血管疾病 《广州日报》 脏功能 超重人群 生活质量
下载PDF
Sensitivity of Precipitation in Aqua-Planet Experiments with an AGCM
5
作者 YU Hai-Yang BAO Qing +2 位作者 ZHOU Lin-Jiong WANG Xiao-Cong LIU Yi-Min 《Atmospheric and Oceanic Science Letters》 CSCD 2014年第1期1-6,共6页
The sensitivity of precipitation was studied by conducting control aqua-planet experiments(APEs) with a model to determine atmospheric general circulation.The model includes two versions: that with a spectral dynamica... The sensitivity of precipitation was studied by conducting control aqua-planet experiments(APEs) with a model to determine atmospheric general circulation.The model includes two versions: that with a spectral dynamical core(SAMIL) and that with a finite-volume dynamical core(FAMIL).Three factors were investigated including dynamical core,time-step length,and horizontal resolution.Numerical results show that the dynamical core significantly affects the structure of zonal averaged precipitation.FAMIL exhibited an equatorial precipitation belt with a single narrow peak,and SAMIL showed a broader belt with double peaks.Moreover,the time step of the model physics is shown to affect the zonal-averaged tropical convective precipitation ratio such that a longer time step leads to more production and consumption of convective available potential energy and convection initiated away from the equator,which corresponds to equatorial double peaks of precipitation.Further,precipitation is determined to be sensitive to horizontal resolution such that higher horizontal resolution allows for more small-scale kinetic energy to be resolved and leads to a broader probability distribution of low-level vertical velocity.This process results in heavier rainfall and convective precipitation extremes in the tropics.Abstract The sensitivity of precipitation was studied by conducting control aqua-planet experiments(APEs)with a model to determine atmospheric general circulation.The model includes two versions:that with a spectral dynamical core(SAMIL)and that with a finite-volume dynamical core(FAMIL).Three factors were investigated including dynamical core,time-step length,and horizontal resolution.Numerical results show that the dynamical core significantly affects the structure of zonal averaged precipitation.FAMIL exhibited an equatorial precipitation belt with a single narrow peak,and SAMIL showed a broader belt with double peaks.Moreover,the time step of the model physics is shown to affect the zonal-averaged tropical convective precipitation ratio such that a longer time step leads to more production and consumption of convective available potential energy and convection initiated away from the equator,which corresponds to equatorial double peaks of precipitation.Further,precipitation is determined to be sensitive to horizontal resolution such that higher horizontal resolution allows for more small-scale kinetic energy to be resolved and leads to a broader probability distribution of low-level vertical velocity.This process results in heavier rainfall and convective precipitation extremes in the tropics. 展开更多
关键词 aqua-planet experiment precipitation sensitivity dynamical core horizontal resolution time step
下载PDF
Noise Reduction and Surge Margin Improvement Using Tapered Diffuser Vane in a Centrifugal Compressor 被引量:3
6
作者 Takashi Goto Eri Ohmoto +1 位作者 Yutaka Ohta Eisuke Outa 《Journal of Thermal Science》 SCIE EI CAS CSCD 2010年第1期21-25,共5页
Improvement of surge margin and reduction of interaction tone noise radiated from a centrifugal compressor with a vaned diffuser is discussed from experiments and CFD analyses.Two types of one-side tapered diffuser va... Improvement of surge margin and reduction of interaction tone noise radiated from a centrifugal compressor with a vaned diffuser is discussed from experiments and CFD analyses.Two types of one-side tapered diffuser vanes,which are shroud-and hub-side tapered vanes,were used in the experiments.The height of the leading edge of the tapered vanes varied from 100% to 10%.Both types of tapered vanes are effective for the reduction of the interaction tone noise radiated from the compressor,because of the smaller interaction area between impeller-discharge flow and diffuser vane surface.Especially,the hub-side tapered diffuser vane suppresses the evolution of the leading-edge vortex,which causes reverse-flow in the diffuser passage.Furthermore,the hub-side tapered diffuser vane,which has an optimized diffuser leading edge shape,can improve the compressor pressure-rise characteristics at low-flow operation and can enlarge the surge margin. 展开更多
关键词 Centrifugal compressor tapered diffuser vane interaction tone noise CFD
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部