OBJECTIVE: To observe capillary blood flow at acupoints during acupuncture treatment of primary dysmenorrhea and gain new insights into its analgesic mechanism. METHODS: Patients with primary dysmenorrhea were enrolle...OBJECTIVE: To observe capillary blood flow at acupoints during acupuncture treatment of primary dysmenorrhea and gain new insights into its analgesic mechanism. METHODS: Patients with primary dysmenorrhea were enrolled and randomly assigned to a treatment or control group. Subjects' symptoms were differentiated into variousTraditional Chinese Medicine(TCM) syndromes and treated for 10 sessions with puncturing acupuncture or self-pressing right-hand Hegu(LI 4), adding other acupoints based on syndrome. Laser speckle was used to compare the change in the vasomotor amplitude and perfusion of the capillaries in Hegu(LI 4) before and during the treatment. Each subject was required to finish the period pain symptoms observation form, verbal rating scales, numerical rating scale, pain rating index, face rating scale, Zung self-rating depression scale, Zung self-rating anxiety scale, and numerical rating scale before and after treatments. RESULTS: After 10 sessions, the symptom scores, pain index(PI), and visual analog scale(VAS) decreased significantly in treatment group. The volume of blood flow in Hegu(LI 4) declined slightly. No significant evidence supported that needling caused capillary contraction, but the capillary vasomotor amplitude at Hegu(LI 4) increased remarkably. CONCLUSION: Acupuncture can increase the capillary blood flow, thus promoting the flow of Qi and blood in terms of TCM theory, which facilitates pain relief.展开更多
Compared with standard logit-based stochastic user equilibrium assignment model,the C-logit model describes route choice behavior in a more realistic way by considering the overlapping effect between routes.This paper...Compared with standard logit-based stochastic user equilibrium assignment model,the C-logit model describes route choice behavior in a more realistic way by considering the overlapping effect between routes.This paper investigates the inefficiency upper bounds of this model against the deterministic system optimum and the C-logit stochastic system optimum in terms of the total network travel time.It is found that the commonality factor of overlapping routes significantly affects the inefficiency bound,besides link congestion degree,total demand and the number of feasible routes.If the commonality factor is not considered,the efficiency loss resulting from selfishly stochastic travel behavior will be to large extent underestimated.展开更多
基金Supported by National Natural Science Foundation(No.81072760)Sino-Austrian Science and Technology Collaboration Program of the Ministry of Science and Technology of the People's Republic of China(ZZ04007)Foundation for Excellent Returnees of Ministry of Human Resources and Social Security of the People's Republic of China,and Research on Specificity of Vasomotor Micrangium in Acupoints Transmitted along Meridians[National Program on Key Basic Research Project(973 Program),2012CB518502]
文摘OBJECTIVE: To observe capillary blood flow at acupoints during acupuncture treatment of primary dysmenorrhea and gain new insights into its analgesic mechanism. METHODS: Patients with primary dysmenorrhea were enrolled and randomly assigned to a treatment or control group. Subjects' symptoms were differentiated into variousTraditional Chinese Medicine(TCM) syndromes and treated for 10 sessions with puncturing acupuncture or self-pressing right-hand Hegu(LI 4), adding other acupoints based on syndrome. Laser speckle was used to compare the change in the vasomotor amplitude and perfusion of the capillaries in Hegu(LI 4) before and during the treatment. Each subject was required to finish the period pain symptoms observation form, verbal rating scales, numerical rating scale, pain rating index, face rating scale, Zung self-rating depression scale, Zung self-rating anxiety scale, and numerical rating scale before and after treatments. RESULTS: After 10 sessions, the symptom scores, pain index(PI), and visual analog scale(VAS) decreased significantly in treatment group. The volume of blood flow in Hegu(LI 4) declined slightly. No significant evidence supported that needling caused capillary contraction, but the capillary vasomotor amplitude at Hegu(LI 4) increased remarkably. CONCLUSION: Acupuncture can increase the capillary blood flow, thus promoting the flow of Qi and blood in terms of TCM theory, which facilitates pain relief.
基金supported by the National Basic Research Program of China under Grant No.2012CB725401the National Natural Science Foundation of China under Grant Nos.71271001 and 71401083the Program for New Century Excellent Talents in University under Grant No.NCET-13-0025
文摘Compared with standard logit-based stochastic user equilibrium assignment model,the C-logit model describes route choice behavior in a more realistic way by considering the overlapping effect between routes.This paper investigates the inefficiency upper bounds of this model against the deterministic system optimum and the C-logit stochastic system optimum in terms of the total network travel time.It is found that the commonality factor of overlapping routes significantly affects the inefficiency bound,besides link congestion degree,total demand and the number of feasible routes.If the commonality factor is not considered,the efficiency loss resulting from selfishly stochastic travel behavior will be to large extent underestimated.
