With abundant wind resources and high pressure imposed on en-vironmental protection, wind power development has a promising future. Butdue to intermittent nature, wind power can bring into full play only if being con-...With abundant wind resources and high pressure imposed on en-vironmental protection, wind power development has a promising future. Butdue to intermittent nature, wind power can bring into full play only if being con-nected into power grid to ensure its supply reliability and continuity, aswell as operational economy. However, technical and market barriers haveprevented wind power from integrating into power grid. To foster wind powerdevelopment, these barriers should be removed by both government incentivepolicies and sophisticated technologies.展开更多
Words are the basic material of language. Vocabulary is one of the important standards for measuring English levels. Mastering a certain amount of vocabulary is the key to learning English well. However, the obstructi...Words are the basic material of language. Vocabulary is one of the important standards for measuring English levels. Mastering a certain amount of vocabulary is the key to learning English well. However, the obstructions of learning vocabulary still exist. According to students＇ psychological features, the author discusses fresh and flexible ways of English vocabulary teaching. It makes vocabulary teaching vivid and easy to understand and memorize. This paper discusses some methods that how the teachers learn to teach words and how the students learn to grasp words, which based on the importance and the current situation of vocabulary teaching in middle school.展开更多
Objective： The aim of our study was to analyze hepatic dysfunction and failure after hepatocellular carcinoma （HCC） resection and relationship of clinical and pathological factors. Methods： Clinical and pathologic...Objective： The aim of our study was to analyze hepatic dysfunction and failure after hepatocellular carcinoma （HCC） resection and relationship of clinical and pathological factors. Methods： Clinical and pathological data of 467 HCC patients was retrospectively reviewed, who underwent liver resection from January 2002 to December 2008 in the Affiliated Hospital of Medical College, Qingdao University, and the post-resectional liver dysfunction and failure risk factors were analyzed by univariate and multivariate analysis. Results： The morbidity of post-resectional liver dysfunction and failure was 1.7% and 2.1%. The post-resectional liver dysfunction and failure after HCC hepatectomy into the statistical analysis： univariate analysis revealed preoperative platelet level （〈 100 × 10^9）, serum albumin level （〈 35 g/L）, serum gamma-Glutamyl transferase （〉 64 U/L）, Child-Pugh classification （B）, MELD score （≥ 9）, intraoperative bleeding （-〉 1000 mL）, blood transfusion were positive factors, multivariate analysis （Logistic） revealed that preoperative platelet level （0.983, 95% CI = 0.971-0.995） and intraoperative blood transfusion （3.145, 95% CI = 1.027-12.028） were independent risk factors for post-resectional liver dysfunction and failure. Conclusion： Prevented liver failure and liver dysfunction occurring after liver resection, it is the key to accurate preoperative assessment of liver function and the patient＇s reserved liver functional, precise hepatectomy and reasonable blockage of hepatic inflow.展开更多
Endothelial cell dysfunction is a term which implies the dysregulation of normal endothelial cell functions,including impairment of the barrier functions,control of vascular tone,disturbance of proliferative and migra...Endothelial cell dysfunction is a term which implies the dysregulation of normal endothelial cell functions,including impairment of the barrier functions,control of vascular tone,disturbance of proliferative and migratory capacity of endothelial cells,as well as control of leukocyte trafficking.Endothelial dysfunction is an early step in vascular inflammatory diseases such as atherosclerosis,diabetic vascular complications,sepsis-induced or severe virus infection-induced organ injuries.The expressions of inflammatory cytokines and vascular adhesion molecules induced by various stimuli,such as modified lipids,smoking,advanced glycation end products and bacteria toxin,significantly contribute to the development of endothelial dysfunction.The transcriptional regulation of inflammatory cytokines and vascular adhesion molecules has been well-studied.However,the regulation of those gene expressions at post-transcriptional level is emerging.RNA-binding proteins have emerged as critical regulators of gene expression acting predominantly at the post-transcriptional level in microRNA-dependent or independent manners.This review summarizes the latest insights into the roles of RNA-binding proteins in controlling vascular endothelial cell functions and their contribution to the pathogenesis of vascular inflammatory diseases.展开更多
文摘With abundant wind resources and high pressure imposed on en-vironmental protection, wind power development has a promising future. Butdue to intermittent nature, wind power can bring into full play only if being con-nected into power grid to ensure its supply reliability and continuity, aswell as operational economy. However, technical and market barriers haveprevented wind power from integrating into power grid. To foster wind powerdevelopment, these barriers should be removed by both government incentivepolicies and sophisticated technologies.
文摘Words are the basic material of language. Vocabulary is one of the important standards for measuring English levels. Mastering a certain amount of vocabulary is the key to learning English well. However, the obstructions of learning vocabulary still exist. According to students＇ psychological features, the author discusses fresh and flexible ways of English vocabulary teaching. It makes vocabulary teaching vivid and easy to understand and memorize. This paper discusses some methods that how the teachers learn to teach words and how the students learn to grasp words, which based on the importance and the current situation of vocabulary teaching in middle school.
文摘Objective： The aim of our study was to analyze hepatic dysfunction and failure after hepatocellular carcinoma （HCC） resection and relationship of clinical and pathological factors. Methods： Clinical and pathological data of 467 HCC patients was retrospectively reviewed, who underwent liver resection from January 2002 to December 2008 in the Affiliated Hospital of Medical College, Qingdao University, and the post-resectional liver dysfunction and failure risk factors were analyzed by univariate and multivariate analysis. Results： The morbidity of post-resectional liver dysfunction and failure was 1.7% and 2.1%. The post-resectional liver dysfunction and failure after HCC hepatectomy into the statistical analysis： univariate analysis revealed preoperative platelet level （〈 100 × 10^9）, serum albumin level （〈 35 g/L）, serum gamma-Glutamyl transferase （〉 64 U/L）, Child-Pugh classification （B）, MELD score （≥ 9）, intraoperative bleeding （-〉 1000 mL）, blood transfusion were positive factors, multivariate analysis （Logistic） revealed that preoperative platelet level （0.983, 95% CI = 0.971-0.995） and intraoperative blood transfusion （3.145, 95% CI = 1.027-12.028） were independent risk factors for post-resectional liver dysfunction and failure. Conclusion： Prevented liver failure and liver dysfunction occurring after liver resection, it is the key to accurate preoperative assessment of liver function and the patient＇s reserved liver functional, precise hepatectomy and reasonable blockage of hepatic inflow.
基金supported by the National Natural Science Foundation of China(91339113,81270202,81070095 to Xin HongBo)the National Basic Research Program of China(2013CB531103 to Xin HongBo)
文摘Endothelial cell dysfunction is a term which implies the dysregulation of normal endothelial cell functions,including impairment of the barrier functions,control of vascular tone,disturbance of proliferative and migratory capacity of endothelial cells,as well as control of leukocyte trafficking.Endothelial dysfunction is an early step in vascular inflammatory diseases such as atherosclerosis,diabetic vascular complications,sepsis-induced or severe virus infection-induced organ injuries.The expressions of inflammatory cytokines and vascular adhesion molecules induced by various stimuli,such as modified lipids,smoking,advanced glycation end products and bacteria toxin,significantly contribute to the development of endothelial dysfunction.The transcriptional regulation of inflammatory cytokines and vascular adhesion molecules has been well-studied.However,the regulation of those gene expressions at post-transcriptional level is emerging.RNA-binding proteins have emerged as critical regulators of gene expression acting predominantly at the post-transcriptional level in microRNA-dependent or independent manners.This review summarizes the latest insights into the roles of RNA-binding proteins in controlling vascular endothelial cell functions and their contribution to the pathogenesis of vascular inflammatory diseases.
