The development of modern agriculture has resulted in much homogenization of the landscape consisting of large patches of farmland,so small remnant non-crop habitats especially linear corridors play an important role ...The development of modern agriculture has resulted in much homogenization of the landscape consisting of large patches of farmland,so small remnant non-crop habitats especially linear corridors play an important role in the conservation of species and the maintenance of ecosystem functions.However,little attention has been paid to the effects of corridors structural characteristics on the plant species restricted to such habitats.In this study,we selected three types of corridors including ditch,hedgerow and road,and analyzed their structural characteristics.The plant species presented in these corridors were investigated,and the species diversity,abundance and frequency were estimated.Moreover,spatial arrangements of corridors were classified into different types to discuss whether there were significant effects of corridor network on plant distribution.The results show that three types of corridors have different effects on plant species composition and diversity.The one-one combined corridor networks and total network associated by three corridors have more complex structural features than each single type of corridor.However,there is no strong correlation between the corridor networks with their plant species.We suggest that carrying out a pointed vegetation survey at corridor intersections to further test the relationships between structural features of corridor and plants is necessary.展开更多
Filgrastim is used to accelerate hematopoietic recovery after ABMT （allogeneic bone marrow transplantation）. Its impact on the total cost of patient care remains to be explored. We therefore undertook a cost effecti...Filgrastim is used to accelerate hematopoietic recovery after ABMT （allogeneic bone marrow transplantation）. Its impact on the total cost of patient care remains to be explored. We therefore undertook a cost effectiveness analysis in the context of a randomized single blinded clinical trial of Filgrastim versus placebo in post ABMT. A primary endpoint, duration of myelosuppression, and three secondary end points （number of days of fever, length of hospital stay, survival at one hundred days） were used to assess efficacy. Direct costs were evaluated and allowed the calculation of the ICER （incremental cost-effectiveness ratios） for the major endpoint of the trial. Sixteen patients were included in the study. The duration of myelosuppression was significantly decreased in the Filgrastim arm with medians of 15 days vs. 19 days in the placebo arm （p = 0.023）. Cost analysis showed no statistically significant difference between the two arms. According to the calculation of ICER, Filgrastim was more costly and more effective than placebo for the number of days of aplasia avoided and the number of days with fever avoided. Placebo strictly dominated filgrastim for days of hospitalization avoided. Filgrastim has proven effective in reducing the duration of aplasia without increasing costs.展开更多
基金Under the auspices of National Natural Science Foundation of China(No.41071118)
文摘The development of modern agriculture has resulted in much homogenization of the landscape consisting of large patches of farmland,so small remnant non-crop habitats especially linear corridors play an important role in the conservation of species and the maintenance of ecosystem functions.However,little attention has been paid to the effects of corridors structural characteristics on the plant species restricted to such habitats.In this study,we selected three types of corridors including ditch,hedgerow and road,and analyzed their structural characteristics.The plant species presented in these corridors were investigated,and the species diversity,abundance and frequency were estimated.Moreover,spatial arrangements of corridors were classified into different types to discuss whether there were significant effects of corridor network on plant distribution.The results show that three types of corridors have different effects on plant species composition and diversity.The one-one combined corridor networks and total network associated by three corridors have more complex structural features than each single type of corridor.However,there is no strong correlation between the corridor networks with their plant species.We suggest that carrying out a pointed vegetation survey at corridor intersections to further test the relationships between structural features of corridor and plants is necessary.
文摘Filgrastim is used to accelerate hematopoietic recovery after ABMT （allogeneic bone marrow transplantation）. Its impact on the total cost of patient care remains to be explored. We therefore undertook a cost effectiveness analysis in the context of a randomized single blinded clinical trial of Filgrastim versus placebo in post ABMT. A primary endpoint, duration of myelosuppression, and three secondary end points （number of days of fever, length of hospital stay, survival at one hundred days） were used to assess efficacy. Direct costs were evaluated and allowed the calculation of the ICER （incremental cost-effectiveness ratios） for the major endpoint of the trial. Sixteen patients were included in the study. The duration of myelosuppression was significantly decreased in the Filgrastim arm with medians of 15 days vs. 19 days in the placebo arm （p = 0.023）. Cost analysis showed no statistically significant difference between the two arms. According to the calculation of ICER, Filgrastim was more costly and more effective than placebo for the number of days of aplasia avoided and the number of days with fever avoided. Placebo strictly dominated filgrastim for days of hospitalization avoided. Filgrastim has proven effective in reducing the duration of aplasia without increasing costs.
