Objectives:To investigate the current situation of palliative care needs and the symptom burden in patients with end-stage renal disease(ESRD)undergoing maintenance hemodialysis(MHD),and to explore whether there are d...Objectives:To investigate the current situation of palliative care needs and the symptom burden in patients with end-stage renal disease(ESRD)undergoing maintenance hemodialysis(MHD),and to explore whether there are differences between younger and older patients.Methods:This cross-sectional study was conducted in the hemodialysis centers of two tertiary hospitals from November 2021 to June 2022.Participants were selected by convenience sampling.Sociodemographics,clinical characteristics,the Palliative Care Outcome Scale(POS),the Dialysis Symptom Index(DSI),and health-related quality of life(EQ-5D-3L)were used for evaluation.Descriptive statistics,between-group comparisons,and correlation analysis were used to analyze the data.Results:A total of 236 patients were enrolled,including 118 younger and 118 older patients.The total median(P25,P75)POS score was 16.0(12.0,23.0),and the score was higher in older patients(P<0.01).The mean total number of symptoms in MHD patients was 15.04±5.06,and the overall median symptom severity score was 59.0(52.0,71.0);these scores were higher in the older group(P<0.01).The most common symptom was dry mouth(91.5%),followed by itching(83.1%),and dry skin(82.2%).Additionally,palliative care needs were significantly associated with symptom burden and health-related quality of life(HRQOL).Conclusions:The results showed that patients with ESRD undergoing MHD have a significant symptom burden and moderate palliative care needs,which are more severe in older patients.Therefore,interdisciplinary teams should be formed to actively manage patients’symptoms and meet the physical,psychological,social,and spiritual needs related to palliative care to improve patients’HRQOL.展开更多
An increase in energy demand leads to further exploration, transportation, and utilization of petroleum, which creates severe soil contamination because of recurrent accidents and oil spills. Remediation of these cont...An increase in energy demand leads to further exploration, transportation, and utilization of petroleum, which creates severe soil contamination because of recurrent accidents and oil spills. Remediation of these contaminated soils is challenging. Among many treatment methods practiced for remediation of petroleum-contaminated soils, surfactant-enhanced soil washing has been widely practiced as a preferred treatment option, as it is a fast and environmentally accepted method. In this paper, we review research undertaken on various anionic, nonionic, cationic, biological, and mixed surfactants for the remediation of petroleum hydrocarbon-contaminated soils. Upcoming surfactants like gemini and switchable surfactants are summarized. We assess the challenges and opportunities of in-situ and ex-situ soil washing, the mechanisms of surfactant-enhanced soil washing, and the criteria to follow for surfactant selection.Furthermore, we briefly discuss the operational and environmental factors affecting soil washing efficiency and soil and surfactant properties affecting surfactant adsorption. We also describe the advantages of coupling soil washing with effluent treatment and surfactant reuse challenges and opportunities. Moreover, challenges and possible new directions for future research on surfactant-enhanced soil washing are proposed.展开更多
文摘Objectives:To investigate the current situation of palliative care needs and the symptom burden in patients with end-stage renal disease(ESRD)undergoing maintenance hemodialysis(MHD),and to explore whether there are differences between younger and older patients.Methods:This cross-sectional study was conducted in the hemodialysis centers of two tertiary hospitals from November 2021 to June 2022.Participants were selected by convenience sampling.Sociodemographics,clinical characteristics,the Palliative Care Outcome Scale(POS),the Dialysis Symptom Index(DSI),and health-related quality of life(EQ-5D-3L)were used for evaluation.Descriptive statistics,between-group comparisons,and correlation analysis were used to analyze the data.Results:A total of 236 patients were enrolled,including 118 younger and 118 older patients.The total median(P25,P75)POS score was 16.0(12.0,23.0),and the score was higher in older patients(P<0.01).The mean total number of symptoms in MHD patients was 15.04±5.06,and the overall median symptom severity score was 59.0(52.0,71.0);these scores were higher in the older group(P<0.01).The most common symptom was dry mouth(91.5%),followed by itching(83.1%),and dry skin(82.2%).Additionally,palliative care needs were significantly associated with symptom burden and health-related quality of life(HRQOL).Conclusions:The results showed that patients with ESRD undergoing MHD have a significant symptom burden and moderate palliative care needs,which are more severe in older patients.Therefore,interdisciplinary teams should be formed to actively manage patients’symptoms and meet the physical,psychological,social,and spiritual needs related to palliative care to improve patients’HRQOL.
基金The financial supports from the National Key Research and Development Program of China (Nos. 2016YFC0400501 and 2016YFC0400502)the Fundamental Research Funds for Central Universities of China (No. 2232018D3-43)the National Natural Science Foundation of China (No. 21277023)
文摘An increase in energy demand leads to further exploration, transportation, and utilization of petroleum, which creates severe soil contamination because of recurrent accidents and oil spills. Remediation of these contaminated soils is challenging. Among many treatment methods practiced for remediation of petroleum-contaminated soils, surfactant-enhanced soil washing has been widely practiced as a preferred treatment option, as it is a fast and environmentally accepted method. In this paper, we review research undertaken on various anionic, nonionic, cationic, biological, and mixed surfactants for the remediation of petroleum hydrocarbon-contaminated soils. Upcoming surfactants like gemini and switchable surfactants are summarized. We assess the challenges and opportunities of in-situ and ex-situ soil washing, the mechanisms of surfactant-enhanced soil washing, and the criteria to follow for surfactant selection.Furthermore, we briefly discuss the operational and environmental factors affecting soil washing efficiency and soil and surfactant properties affecting surfactant adsorption. We also describe the advantages of coupling soil washing with effluent treatment and surfactant reuse challenges and opportunities. Moreover, challenges and possible new directions for future research on surfactant-enhanced soil washing are proposed.
