Conversion of SrSO4 to acidic strontium oxalate hydrate(H[Sr(C2O4)1.5(H2O)]) in aqueous H2C2O4 solutions proceeds as a consecutive reaction. In the first step of the consecutive reaction, SrSO4 reacts with H2C2O4 and ...Conversion of SrSO4 to acidic strontium oxalate hydrate(H[Sr(C2O4)1.5(H2O)]) in aqueous H2C2O4 solutions proceeds as a consecutive reaction. In the first step of the consecutive reaction, SrSO4 reacts with H2C2O4 and pseudomorphic conversion to SrC2 O4·H2O occurs. In the second step, SrC2 O4·H2O reacts with H2C2O4 to form H[Sr(C2 O4)1.5(H2O)]. Sr(HC2 O4)(C2 O4)0.5·H2 O crystallizes during cooling of the reaction mixture to room temperature if the solution reaches the saturation concentration of (H[Sr(C2O4)1.5(H2O)]. The aims of this study are the derivation of reaction rate equations and the determination of the kinetic parameters such as pre-exponential factor, apparent activation energy and order of H2C2O4 concentration for each reaction step.Fractional conversions of SrSO4 were calculated using the quantitative amounts of dissolved S and Sr. It was determined that the reaction rate increased at the initial time of reaction by increasing the temperature using solutions with approximately same H2C2O4 concentrations. The reaction extends very slowly after a certain time in solutions with low H2C2O4 concentration and ends by the formation of a protective layer of SrC2O4-H2O around the surfaces of solid particles. Fractional conversion of SrSO4 is increased by increasing concentration of H2C2O4 at constant temperature. Kinetic model equations were derived using shrinking core model for each step.展开更多
Objective To evaluate the predictive factors of refractory glaucoma treated with diode laser transscleral cyclophotocoagulation(TSCP) in a midterm observation.Methods Fifty-four consecutive patients(54 eyes) with refr...Objective To evaluate the predictive factors of refractory glaucoma treated with diode laser transscleral cyclophotocoagulation(TSCP) in a midterm observation.Methods Fifty-four consecutive patients(54 eyes) with refractory glaucoma were enrolled and underwent TSCP(power of 1.5-2.0 W,exposure time of 2 seconds and 20-50 applications).Patients were regularly followed up for 12 months.Intraocular pressure(IOP) was measured before TSCP treatment and at each follow-up visit.Patients were divided into the sensitive and insensitive groups according to the effect of a single treatment of TSCP on IOP.The success rate was defined as the percentage of eyes achieving an IOP between 5 and 21 mm Hg following TSCP therapy at their final follow up visit.Difference of age between the sensitive and insensitive groups was evaluated with Independent-samples T test and that of gender distribution of two groups was evaluated with Fisher's exact test.The success rate of different types of glaucoma to TSCP was calculated.Results A total of 32 patients were sensitive to TSCP(sensitive group) and 22 patients were insensitive to TSCP(insensitive group).The success rates of female(77.8%,14/18) and cases being over 50 years(71.4%,20/28) were higher than those of male(50.0%,18/36) and ones being under 50 years(46.2%,12/26)(all P>0.05).The age of the sensitive and insensitive groups was 56.0±15.5 and 46.4±15.4 years,respectively(P=0.029).The age(P=0.029) and gender distribution(P=0.046) of the two groups had significant difference.The success rate of neovascular glaucoma,primary angle-closure glaucoma,primary open angle glaucoma,traumatic glaucoma,uveitic glaucoma,and secondary glaucoma after silicone oil injection to TSCP was 57.1%,100.0%,50.0%,20.0%,81.8%,and 0%,respectively.Conclusion Age,gender,and type of glaucoma appear to be associated with effect of TSCP on IOP control.展开更多
Complete conversion of resid into light oil needs to consume large amount of hydrogen, because the light oil has higher hydrogen content. The conversion of whole resid into light oil is not economic at the normal pric...Complete conversion of resid into light oil needs to consume large amount of hydrogen, because the light oil has higher hydrogen content. The conversion of whole resid into light oil is not economic at the normal price gap between the light and heavy oils. Hence a combination of hydrogenation process with carbon removal process is generally adopted.The heavy solvent deasphalting can selectively remove the asphaltenes and metals contained in resid while providing a large amount of easily convertible deasphalted oil for the down-stream processes.This article refers to the characteristics of heavy solvent deasphalting and its application in sour resid processing, along with various routes for utilization of deoiled asphalt.展开更多
The series of Harry Potter and the series of The Hunger Games are the most frequently mentioned children's and youngster's stories after The Adventures of Tom Sawyer. Both of them are children's and youngster's fa...The series of Harry Potter and the series of The Hunger Games are the most frequently mentioned children's and youngster's stories after The Adventures of Tom Sawyer. Both of them are children's and youngster's favorite stories. All of them are about children's adventures. But because of the time and history, they represent different themes of the time. This research paper aims at analyzing the Game Spirits in the first two. The suspense and surprise, fantastic adventures and time interweaving are shown in Harry Potter and the Prisoner of Azkaban. And the unbelievable background, the lucky number, image of gamble, and the game against humanity are the Game Spirits in The Hunger Games. The purpose of this thesis is to help people better understand Harry Potter and The Hunger Games in the aspect of Game Spirit. Harry Potter is the full of fantastic adventure while The Hunger Game is a story full of survival.展开更多
Problem about adolescent drinking has accelerated. Although the alcohol advertisements are restricted by Thai law, nevertheless the alcohol manufactures could still find their way to convey the message about their pro...Problem about adolescent drinking has accelerated. Although the alcohol advertisements are restricted by Thai law, nevertheless the alcohol manufactures could still find their way to convey the message about their products to their consumers, including the adolescents in the school system through several marketing communication tactics. To this study, investigated opinion of Thai teens on alcohol use specific to.. (1) types of alcoholic beverages preferred; (2) reason at first alcohol use; (3) future drinking intention; and (4) perceptions toward alcohol marketing communication. The cross-sectional survey was conducted on 5184 students from grades 4th-12th and vocational school in seven regions of Thailand. The data from questionnaires were analyzed using simple descriptive statistic, frequency distribution, and percentages. Those teens reported to start drinking beer because of wanting to experiment with alcohol (41.3%), to celebrate in special occasion (29.2%), and due to friends involved (15.7%). Majority of teens in this study (〉 80%) disagree or strongly disagree with persuasive message of alcohol advertised through several media channels. Most of the samples have good media literacy, know the intention of the marketing communication of the alcohol manufacturers, and could not be persuaded easily. The results required further evaluation for influence of alcohol marketing communication on students' alcohol expectancy and alcohol use for proper policy recommendation and management.展开更多
To improve the covalent immobilization of penicillin acylase (PA), macromolecular crowding theory was applied to its immobilization. Influence of mass ratio of enzyme to the silica, as well as, activation time with ...To improve the covalent immobilization of penicillin acylase (PA), macromolecular crowding theory was applied to its immobilization. Influence of mass ratio of enzyme to the silica, as well as, activation time with glutaraldehyde on the activity of assembled PA, was studied. In the mesopores, the effect of fl-cyclodextrin (β-CD) on the immobilization of the enzyme was also investigated. It was remarkable that the coupled yield and relative activity reached 99.5% and 92.3%, respectively, when penicillin acylase assembled covalently in the mesopores. The results here indicate that mimicked macromolecule crowding could significantly ameliorate the performance of covalently immobilized PA.展开更多
Objective:The aim of this study was to assess the differences in clinical appearance and prognosis of osteosarcoma between preadolescent and adolescent in Chinese patients and investigate whether age at diagnosis is a...Objective:The aim of this study was to assess the differences in clinical appearance and prognosis of osteosarcoma between preadolescent and adolescent in Chinese patients and investigate whether age at diagnosis is a prognostic indicator.Methods:Between May 2002 and May 2009,ninety-six children with high-grade osteosarcoma treated at our institute were stratified according to the age of 10.There were 19 preadolescents(≤ 10 years) and 77 adolescents(10 years < age ≤ 19 years),and their medical records were reviewed and compared using Fisher exact tests.Overall survival and disease-free survival was estimated by Kaplan-Meier methods and compared using log-rank tests.The prognostic significance of the various factors on survival was examined by Cox regression analysis.Results:There were no significant differences in terms of Karnofsky Performance Status(KPS) score,Enneking stage,tumor location,histologic type,pathologic fracture,tumor necrosis rate,tumor size,relapse and frequencies of adjuvant chemotherapy between the two groups.A high proportion of preadolescent patients was treated with amputation(78.9% vs.44.2%;P = 0.01).The 5-year survival of the preadolescent and adolescent groups was(38 ± 14)% and(33 ± 10)%,and the 2-year disease free survival for each group was(45 ± 12)% and(44.4 ± 6.3)%,respectively.Our study showed that age did not have any statistical significance for survival(P = 0.803).Univariate analysis indicated that KPS score;frequencies of adjuvant chemotherapy,tumor size and relapse were significantly related to overall survival.Multivariate Cox regression analysis revealed that both frequencies of adjuvant chemotherapy and relapse were independently prognostic factors for survival.Conclusion:Clinical characteristics and survival between the preadolescents and adolescents with osteosarcoma in China were compatible.So we suggested that there did not need to treat preadolescents patients by alternative and/or aggressive therapies compared with adolescent patients.展开更多
Suicide is one of the leading causes of teenagers' deaths. Even whether it is preventable, most of the time, there are still very few projects or actions of the local authorities and/or organisations in Romania, due ...Suicide is one of the leading causes of teenagers' deaths. Even whether it is preventable, most of the time, there are still very few projects or actions of the local authorities and/or organisations in Romania, due to the lack of information and resources. The suicide prevention line for children and teenagers in Bucharest is presented and evaluated after five years of activity. It may be considered as one example of good practice, since it managed to put together local knowledge, human resources, and social actors. The suicide prevention line for children and teenagers in Bucharest has been established in 2009 by the General Directorate of Social Welfare of Bucharest Municipality, in partnership with the Psychiatric Hospital "Prof. dr. Alexandru Obregia". The finances are provided by the Welfare Department, the location belongs to the Psychiatric Hospital, and the mental health services are coordinated by a neuro-psychiatrist. There are about 30 volunteers taking the phone calls 24/7. Since 2011, they established the Association of Suicidology.展开更多
The effect of various concentrations of 2-hydroxypropyl-β-cyclodextrin (HP-β-CD) on the solubility of dihydroartemisinin (DHA) in aqueous solution at different pHs was investigated. The influence of different co...The effect of various concentrations of 2-hydroxypropyl-β-cyclodextrin (HP-β-CD) on the solubility of dihydroartemisinin (DHA) in aqueous solution at different pHs was investigated. The influence of different concentrations of 2-hydroxypropyl-β- eyclodextrin on the stability of dihydroartemisinin at 50, 60, 70 and 80 ℃ was also studied. Inclusion complex of dihydroartemisinin with 2-hydroxypropyl-β-cyclodextrin was prepared and characterized by X-ray diffraction and differential scanning calorimetry. The 2-hydroxypropyl-β-cyclodextrin effectively inhibited the hydrolysis of dihydroartemisinin and greatly increased its solubility. Furthermore, we showed that the higher concentrations of 2-hydroxypropyl-β-cyclodextrin, the better stability and solubility of dihydroartemisinin. When the temperature was increased, the stability of dihydroartemisinin decreased. Our results indicated that 2-hydroxypropyl-β-cyclodextrin can be used as a stabilizer and solubilizer of dihydroartemisinin.展开更多
基金the financial support of the Scientific Research Projects Coordination Unit of Istanbul University (Project number: 17344 and 31088)
文摘Conversion of SrSO4 to acidic strontium oxalate hydrate(H[Sr(C2O4)1.5(H2O)]) in aqueous H2C2O4 solutions proceeds as a consecutive reaction. In the first step of the consecutive reaction, SrSO4 reacts with H2C2O4 and pseudomorphic conversion to SrC2 O4·H2O occurs. In the second step, SrC2 O4·H2O reacts with H2C2O4 to form H[Sr(C2 O4)1.5(H2O)]. Sr(HC2 O4)(C2 O4)0.5·H2 O crystallizes during cooling of the reaction mixture to room temperature if the solution reaches the saturation concentration of (H[Sr(C2O4)1.5(H2O)]. The aims of this study are the derivation of reaction rate equations and the determination of the kinetic parameters such as pre-exponential factor, apparent activation energy and order of H2C2O4 concentration for each reaction step.Fractional conversions of SrSO4 were calculated using the quantitative amounts of dissolved S and Sr. It was determined that the reaction rate increased at the initial time of reaction by increasing the temperature using solutions with approximately same H2C2O4 concentrations. The reaction extends very slowly after a certain time in solutions with low H2C2O4 concentration and ends by the formation of a protective layer of SrC2O4-H2O around the surfaces of solid particles. Fractional conversion of SrSO4 is increased by increasing concentration of H2C2O4 at constant temperature. Kinetic model equations were derived using shrinking core model for each step.
文摘Objective To evaluate the predictive factors of refractory glaucoma treated with diode laser transscleral cyclophotocoagulation(TSCP) in a midterm observation.Methods Fifty-four consecutive patients(54 eyes) with refractory glaucoma were enrolled and underwent TSCP(power of 1.5-2.0 W,exposure time of 2 seconds and 20-50 applications).Patients were regularly followed up for 12 months.Intraocular pressure(IOP) was measured before TSCP treatment and at each follow-up visit.Patients were divided into the sensitive and insensitive groups according to the effect of a single treatment of TSCP on IOP.The success rate was defined as the percentage of eyes achieving an IOP between 5 and 21 mm Hg following TSCP therapy at their final follow up visit.Difference of age between the sensitive and insensitive groups was evaluated with Independent-samples T test and that of gender distribution of two groups was evaluated with Fisher's exact test.The success rate of different types of glaucoma to TSCP was calculated.Results A total of 32 patients were sensitive to TSCP(sensitive group) and 22 patients were insensitive to TSCP(insensitive group).The success rates of female(77.8%,14/18) and cases being over 50 years(71.4%,20/28) were higher than those of male(50.0%,18/36) and ones being under 50 years(46.2%,12/26)(all P>0.05).The age of the sensitive and insensitive groups was 56.0±15.5 and 46.4±15.4 years,respectively(P=0.029).The age(P=0.029) and gender distribution(P=0.046) of the two groups had significant difference.The success rate of neovascular glaucoma,primary angle-closure glaucoma,primary open angle glaucoma,traumatic glaucoma,uveitic glaucoma,and secondary glaucoma after silicone oil injection to TSCP was 57.1%,100.0%,50.0%,20.0%,81.8%,and 0%,respectively.Conclusion Age,gender,and type of glaucoma appear to be associated with effect of TSCP on IOP control.
文摘Complete conversion of resid into light oil needs to consume large amount of hydrogen, because the light oil has higher hydrogen content. The conversion of whole resid into light oil is not economic at the normal price gap between the light and heavy oils. Hence a combination of hydrogenation process with carbon removal process is generally adopted.The heavy solvent deasphalting can selectively remove the asphaltenes and metals contained in resid while providing a large amount of easily convertible deasphalted oil for the down-stream processes.This article refers to the characteristics of heavy solvent deasphalting and its application in sour resid processing, along with various routes for utilization of deoiled asphalt.
文摘The series of Harry Potter and the series of The Hunger Games are the most frequently mentioned children's and youngster's stories after The Adventures of Tom Sawyer. Both of them are children's and youngster's favorite stories. All of them are about children's adventures. But because of the time and history, they represent different themes of the time. This research paper aims at analyzing the Game Spirits in the first two. The suspense and surprise, fantastic adventures and time interweaving are shown in Harry Potter and the Prisoner of Azkaban. And the unbelievable background, the lucky number, image of gamble, and the game against humanity are the Game Spirits in The Hunger Games. The purpose of this thesis is to help people better understand Harry Potter and The Hunger Games in the aspect of Game Spirit. Harry Potter is the full of fantastic adventure while The Hunger Game is a story full of survival.
文摘Problem about adolescent drinking has accelerated. Although the alcohol advertisements are restricted by Thai law, nevertheless the alcohol manufactures could still find their way to convey the message about their products to their consumers, including the adolescents in the school system through several marketing communication tactics. To this study, investigated opinion of Thai teens on alcohol use specific to.. (1) types of alcoholic beverages preferred; (2) reason at first alcohol use; (3) future drinking intention; and (4) perceptions toward alcohol marketing communication. The cross-sectional survey was conducted on 5184 students from grades 4th-12th and vocational school in seven regions of Thailand. The data from questionnaires were analyzed using simple descriptive statistic, frequency distribution, and percentages. Those teens reported to start drinking beer because of wanting to experiment with alcohol (41.3%), to celebrate in special occasion (29.2%), and due to friends involved (15.7%). Majority of teens in this study (〉 80%) disagree or strongly disagree with persuasive message of alcohol advertised through several media channels. Most of the samples have good media literacy, know the intention of the marketing communication of the alcohol manufacturers, and could not be persuaded easily. The results required further evaluation for influence of alcohol marketing communication on students' alcohol expectancy and alcohol use for proper policy recommendation and management.
基金Supported by the National High Technology Research and Development Program of China (863 Program, No.2006AA02Z211), the National Natural Science Foundation of China (No.20376034), the Natural Science Foundation of Jiangsu Province of China (BK2006181), and the Scientific Research Foundation for Young Teachers in the Higher Education Institutions of Anhui Province of China (2005jq1163), and the Foundation of Jiangsu Province of China for College Postgraduate Students in Inno-vation Engineering (2007).
文摘To improve the covalent immobilization of penicillin acylase (PA), macromolecular crowding theory was applied to its immobilization. Influence of mass ratio of enzyme to the silica, as well as, activation time with glutaraldehyde on the activity of assembled PA, was studied. In the mesopores, the effect of fl-cyclodextrin (β-CD) on the immobilization of the enzyme was also investigated. It was remarkable that the coupled yield and relative activity reached 99.5% and 92.3%, respectively, when penicillin acylase assembled covalently in the mesopores. The results here indicate that mimicked macromolecule crowding could significantly ameliorate the performance of covalently immobilized PA.
基金Supported by grants from the National Natural Science Foundation of China (No. 81001191)Science and Technology Commission of Shanghai (No. 10PJ1408300)
文摘Objective:The aim of this study was to assess the differences in clinical appearance and prognosis of osteosarcoma between preadolescent and adolescent in Chinese patients and investigate whether age at diagnosis is a prognostic indicator.Methods:Between May 2002 and May 2009,ninety-six children with high-grade osteosarcoma treated at our institute were stratified according to the age of 10.There were 19 preadolescents(≤ 10 years) and 77 adolescents(10 years < age ≤ 19 years),and their medical records were reviewed and compared using Fisher exact tests.Overall survival and disease-free survival was estimated by Kaplan-Meier methods and compared using log-rank tests.The prognostic significance of the various factors on survival was examined by Cox regression analysis.Results:There were no significant differences in terms of Karnofsky Performance Status(KPS) score,Enneking stage,tumor location,histologic type,pathologic fracture,tumor necrosis rate,tumor size,relapse and frequencies of adjuvant chemotherapy between the two groups.A high proportion of preadolescent patients was treated with amputation(78.9% vs.44.2%;P = 0.01).The 5-year survival of the preadolescent and adolescent groups was(38 ± 14)% and(33 ± 10)%,and the 2-year disease free survival for each group was(45 ± 12)% and(44.4 ± 6.3)%,respectively.Our study showed that age did not have any statistical significance for survival(P = 0.803).Univariate analysis indicated that KPS score;frequencies of adjuvant chemotherapy,tumor size and relapse were significantly related to overall survival.Multivariate Cox regression analysis revealed that both frequencies of adjuvant chemotherapy and relapse were independently prognostic factors for survival.Conclusion:Clinical characteristics and survival between the preadolescents and adolescents with osteosarcoma in China were compatible.So we suggested that there did not need to treat preadolescents patients by alternative and/or aggressive therapies compared with adolescent patients.
文摘Suicide is one of the leading causes of teenagers' deaths. Even whether it is preventable, most of the time, there are still very few projects or actions of the local authorities and/or organisations in Romania, due to the lack of information and resources. The suicide prevention line for children and teenagers in Bucharest is presented and evaluated after five years of activity. It may be considered as one example of good practice, since it managed to put together local knowledge, human resources, and social actors. The suicide prevention line for children and teenagers in Bucharest has been established in 2009 by the General Directorate of Social Welfare of Bucharest Municipality, in partnership with the Psychiatric Hospital "Prof. dr. Alexandru Obregia". The finances are provided by the Welfare Department, the location belongs to the Psychiatric Hospital, and the mental health services are coordinated by a neuro-psychiatrist. There are about 30 volunteers taking the phone calls 24/7. Since 2011, they established the Association of Suicidology.
文摘The effect of various concentrations of 2-hydroxypropyl-β-cyclodextrin (HP-β-CD) on the solubility of dihydroartemisinin (DHA) in aqueous solution at different pHs was investigated. The influence of different concentrations of 2-hydroxypropyl-β- eyclodextrin on the stability of dihydroartemisinin at 50, 60, 70 and 80 ℃ was also studied. Inclusion complex of dihydroartemisinin with 2-hydroxypropyl-β-cyclodextrin was prepared and characterized by X-ray diffraction and differential scanning calorimetry. The 2-hydroxypropyl-β-cyclodextrin effectively inhibited the hydrolysis of dihydroartemisinin and greatly increased its solubility. Furthermore, we showed that the higher concentrations of 2-hydroxypropyl-β-cyclodextrin, the better stability and solubility of dihydroartemisinin. When the temperature was increased, the stability of dihydroartemisinin decreased. Our results indicated that 2-hydroxypropyl-β-cyclodextrin can be used as a stabilizer and solubilizer of dihydroartemisinin.