The aim of this study was to determine if either Helicobacter or enterotoxigen ic Bacteroides fragilis (ETBF) was linked to inflammatory bowel disease (IBD), u sing PCR. We analyzed the luminal washings and colonic bi...The aim of this study was to determine if either Helicobacter or enterotoxigen ic Bacteroides fragilis (ETBF) was linked to inflammatory bowel disease (IBD), u sing PCR. We analyzed the luminal washings and colonic biopsies of 35 patients w ith IBD and 37 control patients. The presence of Helicobacter was confirmed in t he luminal washing of one IBD patient and three control patients and in the biop sies of two IBD patients. Ten of 28 control patients and 8 of 32 IBD patients ha d a positive luminal washing for the enterotoxin gene. Six of 33 control patient s and 4 of 32 IBD patients had positive biopsies. The prevalence of the enteroto xin gene was higher in IBD patients with active disease compared with patients w ith inactive disease, although it did not achieve statistical significance. In c onclusion, Helicobacter was not associated with IBD in our population of patient s, although ETBF may be associated with active disease.展开更多
文摘The aim of this study was to determine if either Helicobacter or enterotoxigen ic Bacteroides fragilis (ETBF) was linked to inflammatory bowel disease (IBD), u sing PCR. We analyzed the luminal washings and colonic biopsies of 35 patients w ith IBD and 37 control patients. The presence of Helicobacter was confirmed in t he luminal washing of one IBD patient and three control patients and in the biop sies of two IBD patients. Ten of 28 control patients and 8 of 32 IBD patients ha d a positive luminal washing for the enterotoxin gene. Six of 33 control patient s and 4 of 32 IBD patients had positive biopsies. The prevalence of the enteroto xin gene was higher in IBD patients with active disease compared with patients w ith inactive disease, although it did not achieve statistical significance. In c onclusion, Helicobacter was not associated with IBD in our population of patient s, although ETBF may be associated with active disease.
