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口腔结外型非何杰金氏恶性淋巴瘤(26例临床病理分析) 被引量:1
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作者 郑伟 张志坚 +1 位作者 吴文乔 曾西池 《口腔医学》 CAS 北大核心 1994年第3期145-147,共3页
口腔结外型非何杰金氏恶性淋巴瘤(26例临床病理分析)福建漳州市医院口腔科郑伟,张志坚福建漳州市医院病理科吴文乔,曾西池恶性淋巴瘤是全身性疾患,病变可发生于淋巴结(结内型)也可累及淋巴结外的组织器官(结外型),后者常发... 口腔结外型非何杰金氏恶性淋巴瘤(26例临床病理分析)福建漳州市医院口腔科郑伟,张志坚福建漳州市医院病理科吴文乔,曾西池恶性淋巴瘤是全身性疾患,病变可发生于淋巴结(结内型)也可累及淋巴结外的组织器官(结外型),后者常发生于胃肠道、鼻咽部、扁桃体等部位,... 展开更多
关键词 非何金淋巴瘤 口腔肿 口腔结外型 病理分析
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p53、bcl-2及bax基因在非何杰金氏恶性淋巴瘤中的表达及意义 被引量:2
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作者 王立生 赵俊生 +3 位作者 潘令嘉 孙勇 张亚历 周殿元 《第一军医大学学报》 CSCD 2000年第5期422-424,共3页
目的 探讨凋亡调控基因p53、bcl-2和bax的蛋白表达及其与非何杰金氏恶性淋巴瘤(NHL)恶性程度之间的关系。方法 运用免疫组化方法检测了62例NHL的凋亡调控基因p53、bcl-2和bax的蛋白表达状态。结果 p53及Bcl-2蛋白的表达率、表达强度... 目的 探讨凋亡调控基因p53、bcl-2和bax的蛋白表达及其与非何杰金氏恶性淋巴瘤(NHL)恶性程度之间的关系。方法 运用免疫组化方法检测了62例NHL的凋亡调控基因p53、bcl-2和bax的蛋白表达状态。结果 p53及Bcl-2蛋白的表达率、表达强度及阳性细胞密度均随NHL恶性程度的发展而逐渐增高,低度恶性组明显低于中度及高度恶性组(P<0.01),而中度及高度恶性组之间则无显著差异(P>0.05);与此相反,Bax蛋白在低度恶性组的表达水平明显高于中度及高度恶性组(P<0.01)。结论 细胞凋亡调控异常在NHL的发生与发展中可能起重要作用,它们的表达状态和NHL的恶性程度密切相关。 展开更多
关键词 何金氏恶性淋巴 细胞凋亡 免疫组织化学
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^(188)Re标记单克隆抗体的应用研究进展(文献综述) 被引量:4
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作者 李贵平 张辉 《放射免疫学杂志》 CAS 2003年第2期113-115,共3页
关键词 放免治疗 放射治疗 白血病 B细胞性何金淋巴 放射性核素 ^188Re标记单克隆抗体 免疫治疗
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Dysentery caused by Balantidium coliin a patient with non-Hodgkin's lymphoma from Turkey 被引量:4
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作者 Süleyman Yazar Fevzi Altuntas +1 位作者 Izzet Sahin Metin Atambay 《World Journal of Gastroenterology》 SCIE CAS CSCD 2004年第3期458-459,共2页
Balantidium coli is the only parasitic ciliate of man. It is a flattened oval organism covered with cilia, and a gullet at the anterior end. It is infrequently pathogenic for man,although epidemic buds in tropical zon... Balantidium coli is the only parasitic ciliate of man. It is a flattened oval organism covered with cilia, and a gullet at the anterior end. It is infrequently pathogenic for man,although epidemic buds in tropical zones have been described. The infection fundamentally affects the colon and causes variable clinic pictures, from asymptomatic to serious dysenteric forms. We present a case of parasitologically diagnosed as causes of diarrhea in a patient with non Hodgkin's lymphoma from Turkey.In order to find out the causative etiologic agent of diarrhea,stool samples were examined by native,lugol and flotation methods and we detected moving trophozoites, which were approximately 60μm long and 35μm wide.These bodies were diagnosed as Balantidium coli This case underlines that Balantidium coli should also be considered as a possible pathogen in immunocompromised patients with diarrhea. 展开更多
关键词 ANIMALS Balantidiasis Balantidium PURIFICATION DYSENTERY Female Humans Lymphoma Non-Hodgkin Middle Aged TURKEY
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CORRELATION BETWEEN THE NUMBER OF MITOTIC FIGURES AND THE PERCENTAGE OF Ki67-POSITIVE CELLS IN NON-HODGKIN’S LYMPHOMAS
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作者 黄高升 FellerAC LennertK 《Chinese Medical Sciences Journal》 CAS CSCD 1994年第1期16-19,共4页
Proliferative activity in 106 cases of non-Hodgkin’s lymphoma was estimated using the monoclonal antibody Ki67 and by counting the number of mitotic figures. The percentage of Ki67-positive cells was compared with th... Proliferative activity in 106 cases of non-Hodgkin’s lymphoma was estimated using the monoclonal antibody Ki67 and by counting the number of mitotic figures. The percentage of Ki67-positive cells was compared with the median number of mitotic figures per square millimeter. Both Ki67 positivity and the number of mitotic figures were found to be greater in high grade than in low grade lymphomas, although there was an overlap between the two grades of malignancy. A close correlation was found between the number of mitotic figures and the percentage of Ki67-positive cells not only in all lymphoma typo taken together (r_s= 0. 834 . P<0. 001). but also in B-cell lymphoma (r_s= 0. 8 1 P< 0. 001) and T-cell lymphoma (r_s = 0. 764. P<0. 00 1) taken seprately. Thus, both methods are useful for the estimation of proliferative activity. but each method has its advantages and disadvantages. 展开更多
关键词 lymphma non-Hodgkin’s mitotic figures monoclonal antibody Ki67
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FDA宣新审核Bexxar
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作者 王峦 《国外药讯》 2003年第5期33-34,共2页
关键词 BEXXAR 抗肿药物 何金淋巴 生物制品
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