AIM: To investigate the frequency of gastroen-terological diseases in the etiology and the efficacy of proton pump inhibitors (PPIs) in the treatment of cardiac syndrome X (CSX) as a subform of non-cardiac chest pain ...AIM: To investigate the frequency of gastroen-terological diseases in the etiology and the efficacy of proton pump inhibitors (PPIs) in the treatment of cardiac syndrome X (CSX) as a subform of non-cardiac chest pain (NCCP). METHODS: We investigated 114 patients with CSX using symptom questionnaires. A subgroup of these patients were investigated regarding upper gastrointestinal disorders (GIs) and treated with PPI. Patients not willing to participate in investigation and treatment served as control group. RESULTS: Thirty-six patients denied any residual symptoms and were not further evaluated. After informed consent in 27 of the remaining 78 patients, we determined the prevalence of disorders of the upper GI tract and quantifi ed the effect of treatment with pantoprazole. We found a high prevalence of gastroenterological pathologies (26/27 patients, 97%)with gastritis, gastroesophageal reflux disease (GERD) and acid reflux as the most common associated disorders. If treated according to the study protocol, these patients showed a significant improvement in the symptom score. Patients treated by primary care physicians, not according to the study protocol had a minor response to treatment (n = 19, -43%), while patients not treated at all (n = 26) had no improvement of symptoms (-0%). CONCLUSION: Disorders of the upper GI tract are a frequent origin of CSX in a German population and can be treated with pantoprazole if given for a longer period.展开更多
The characteristics of climatic change and fiver runoff, as well as the response of fiver runoff to climatic change in the northern Xinjiang are analyzed on the basis of the hydrological and meteorological data over t...The characteristics of climatic change and fiver runoff, as well as the response of fiver runoff to climatic change in the northern Xinjiang are analyzed on the basis of the hydrological and meteorological data over the last 50 years by the methods of Mann-Kendall nonparametric test and the nonlinear regression model. The results show that: 1) The temperature and the precipitation increased significantly in the whole northern Xinjiang, but the precipitation displayed no obvious change, or even a decreasing trend in the northern mountainous area of the northern Xinjiang. 2) River runoff varied in different regions in the northern Xinjiang. It significantly increased in the northern slope of the Tianshan Mountains and the north of the northern Xinjiang (p = 0.05), while slightly ificreased in the west of the northern Xinjiang. 3) North Atlantic Oscillation (NAO) affects fiver runoff by influencing temperature and precipitation. The NAO and precipitation had apparent significant correlations with the fiver runoff, but the temperature did not in the northern Xinjiang. Since the mid-1990s fiver runoff increase was mainly caused by the increasing temperature in the northern slope of the Tianshan Mountains and the north of the northern Xinjiang. Increased precipitation resulted in increased fiver runoff in the west of the northern Xinjiang.展开更多
文摘AIM: To investigate the frequency of gastroen-terological diseases in the etiology and the efficacy of proton pump inhibitors (PPIs) in the treatment of cardiac syndrome X (CSX) as a subform of non-cardiac chest pain (NCCP). METHODS: We investigated 114 patients with CSX using symptom questionnaires. A subgroup of these patients were investigated regarding upper gastrointestinal disorders (GIs) and treated with PPI. Patients not willing to participate in investigation and treatment served as control group. RESULTS: Thirty-six patients denied any residual symptoms and were not further evaluated. After informed consent in 27 of the remaining 78 patients, we determined the prevalence of disorders of the upper GI tract and quantifi ed the effect of treatment with pantoprazole. We found a high prevalence of gastroenterological pathologies (26/27 patients, 97%)with gastritis, gastroesophageal reflux disease (GERD) and acid reflux as the most common associated disorders. If treated according to the study protocol, these patients showed a significant improvement in the symptom score. Patients treated by primary care physicians, not according to the study protocol had a minor response to treatment (n = 19, -43%), while patients not treated at all (n = 26) had no improvement of symptoms (-0%). CONCLUSION: Disorders of the upper GI tract are a frequent origin of CSX in a German population and can be treated with pantoprazole if given for a longer period.
基金Under the auspices of Knowledge Innovation Programs of Chinese Academy of Sciences (No. KZCX2-YW-127, KZCX2-XB2-03-01, KZCX2-Q10-5-4)
文摘The characteristics of climatic change and fiver runoff, as well as the response of fiver runoff to climatic change in the northern Xinjiang are analyzed on the basis of the hydrological and meteorological data over the last 50 years by the methods of Mann-Kendall nonparametric test and the nonlinear regression model. The results show that: 1) The temperature and the precipitation increased significantly in the whole northern Xinjiang, but the precipitation displayed no obvious change, or even a decreasing trend in the northern mountainous area of the northern Xinjiang. 2) River runoff varied in different regions in the northern Xinjiang. It significantly increased in the northern slope of the Tianshan Mountains and the north of the northern Xinjiang (p = 0.05), while slightly ificreased in the west of the northern Xinjiang. 3) North Atlantic Oscillation (NAO) affects fiver runoff by influencing temperature and precipitation. The NAO and precipitation had apparent significant correlations with the fiver runoff, but the temperature did not in the northern Xinjiang. Since the mid-1990s fiver runoff increase was mainly caused by the increasing temperature in the northern slope of the Tianshan Mountains and the north of the northern Xinjiang. Increased precipitation resulted in increased fiver runoff in the west of the northern Xinjiang.