男性乳腺癌(male breast cancer,MBC)是一种临床少见的恶性肿瘤,占全部乳腺癌病例的1%左右,在男性恶性肿瘤发病中则不足1%。而MBC伴发其他原发性恶性肿瘤尤为罕见,多为个案报道,特别是合并发病率低下的血液系统恶性肿瘤如白血病,近10...男性乳腺癌(male breast cancer,MBC)是一种临床少见的恶性肿瘤,占全部乳腺癌病例的1%左右,在男性恶性肿瘤发病中则不足1%。而MBC伴发其他原发性恶性肿瘤尤为罕见,多为个案报道,特别是合并发病率低下的血液系统恶性肿瘤如白血病,近10年来报道的白血病伴发MBC发病的仅有国外报道的2例,展开更多
Background. Non-Hodgkin’s lymphoma (NHL) presenting as a gynecologic malignancy is exceedingly rare. We present two cases of NHL presenting as primary ovarian and cervical cancer, respectively. Case. A 66- year- old ...Background. Non-Hodgkin’s lymphoma (NHL) presenting as a gynecologic malignancy is exceedingly rare. We present two cases of NHL presenting as primary ovarian and cervical cancer, respectively. Case. A 66- year- old female presented with abdominal bloating and increased abdominal girth. She underwent a supracervical hysterectomy, bilateral salpingo-oophorectomy, and omentectomy fora large pelvic mass. Immunophenotyping/flow cytometry revealed monoclonal B-cells positive for the CD 20 marker, consistent with NHL. A 47- year- old female presented with persistent vaginal discharge and an ulcerative lesion of the cervix. Cervical biopsies were non-diagnostic for carcinoma but immunophenotyping demonstrated CD 20 positive B- cells, consistent with NHL. Conclusion. Although uncommon, lymphoma should be included in the differential diagnosis of gynecologic malignancies because of a favorable outcome when properly diagnosed and treated.展开更多
文摘男性乳腺癌(male breast cancer,MBC)是一种临床少见的恶性肿瘤,占全部乳腺癌病例的1%左右,在男性恶性肿瘤发病中则不足1%。而MBC伴发其他原发性恶性肿瘤尤为罕见,多为个案报道,特别是合并发病率低下的血液系统恶性肿瘤如白血病,近10年来报道的白血病伴发MBC发病的仅有国外报道的2例,
文摘Background. Non-Hodgkin’s lymphoma (NHL) presenting as a gynecologic malignancy is exceedingly rare. We present two cases of NHL presenting as primary ovarian and cervical cancer, respectively. Case. A 66- year- old female presented with abdominal bloating and increased abdominal girth. She underwent a supracervical hysterectomy, bilateral salpingo-oophorectomy, and omentectomy fora large pelvic mass. Immunophenotyping/flow cytometry revealed monoclonal B-cells positive for the CD 20 marker, consistent with NHL. A 47- year- old female presented with persistent vaginal discharge and an ulcerative lesion of the cervix. Cervical biopsies were non-diagnostic for carcinoma but immunophenotyping demonstrated CD 20 positive B- cells, consistent with NHL. Conclusion. Although uncommon, lymphoma should be included in the differential diagnosis of gynecologic malignancies because of a favorable outcome when properly diagnosed and treated.