This paper describes an innovative, genetic algorithm based inverse model of nonlinear transducer. In the inverse modeling, using a genetic algorithm, the unknown coefficients of the model are estimated accurately. T...This paper describes an innovative, genetic algorithm based inverse model of nonlinear transducer. In the inverse modeling, using a genetic algorithm, the unknown coefficients of the model are estimated accurately. The simulation results indicate that this technique provides greater flexibility and suitability than the existing methods. It is very easy to modify the nonlinear transducer on line. Thus the method improves the transducer's accuracy. With the help of genetic algorithm (GA), the model coefficients' training are less likely to be trapped in local minima than traditional gradient based search algorithms.展开更多
To improve the performance of fuel cells, the operating temperature of molten carbonate fuel cell (MCFC) stack should be controlled within a specified range. In this paper, with the RBF neural network’s ability of id...To improve the performance of fuel cells, the operating temperature of molten carbonate fuel cell (MCFC) stack should be controlled within a specified range. In this paper, with the RBF neural network’s ability of identifying complex nonlinear systems, a neural network identification model of MCFC stack is developed based on the sampled input-output data. Also, a novel online fuzzy control procedure for the temperature of MCFC stack is developed based on the fuzzy genetic algorithm (FGA). Parameters and rules of the fuzzy controller are optimized. With the neural network identification model, simulation of MCFC stack control is carried out. Validity of the model and the superior performance of the fuzzy controller are demonstrated.展开更多
Hereditary non-polyposis colorectal carcinoma (HNPCC) is an autosomal dominant disorder associated with colorectal and endometrial cancer and a range of other tumor types. Germline mutations in the DNA mismatch repa...Hereditary non-polyposis colorectal carcinoma (HNPCC) is an autosomal dominant disorder associated with colorectal and endometrial cancer and a range of other tumor types. Germline mutations in the DNA mismatch repair (MMR) genes, particularly MLH1, MEH2, and MEH5, underlie this disorder. The vast majority of these HNPCC-associated mutations have been proven, or assumed, given the family history of cancer, to be transmitted through several generations. To the best of our knowledge, only a single case of a de novo germline MMR gene mutation (in MEH2) has been reported till now. Here, we report a patient with a de novo mutation in MLH1. We identified a MLH1 Q701X truncating mutation in the blood lymphocytes of a male who had been diagnosed with rectal cancer at the age of 35. His family history of cancer was negative for the first- and second-degree relatives. The mutation could not be detected in the patient's parents and sibling and paternity was confirmed with a set of highly polymorphic markers. Non-penetrance and small family size is the common explanation of verified negative family histories of cancer in patients with a germline MMR gene mutation. However, in addition to some cases explained by non-paternity, de novo germline mutations should be considered as a possible explanation as well. As guidelines that stress not to restrict MMR gene mutation testing to patients with a positive family history are more widely introduced, more cases of de novo MMR gene germline mutations may be revealed.展开更多
A model of correcting the nonlinear error of photoelectric displacement sensor was established based on the least square support vector machine.The parameters of the correcting nonlinear model,such as penalty factor a...A model of correcting the nonlinear error of photoelectric displacement sensor was established based on the least square support vector machine.The parameters of the correcting nonlinear model,such as penalty factor and kernel parameter,were optimized by chaos genetic algorithm.And the nonlinear correction of photoelectric displacement sensor based on least square support vector machine was applied.The application results reveal that error of photoelectric displacement sensor is less than 1.5%,which is rather satisfactory for nonlinear correction of photoelectric displacement sensor.展开更多
In the typhoon adaptive observation based on conditional nonlinear optimal perturbation (CNOP), the ‘on-off’ switch caused by moist physical parameterization in prediction models prevents the conventional adjoint me...In the typhoon adaptive observation based on conditional nonlinear optimal perturbation (CNOP), the ‘on-off’ switch caused by moist physical parameterization in prediction models prevents the conventional adjoint method from providing correct gradient during the optimization process. To address this problem, the capture of CNOP, when the "on-off" switches are included in models, is treated as non-smooth optimization in this study, and the genetic algorithm (GA) is introduced. After detailed algorithm procedures are formulated using an idealized model with parameterization "on-off" switches in the forcing term, the impacts of "on-off" switches on the capture of CNOP are analyzed, and three numerical experiments are conducted to check the effectiveness of GA in capturing CNOP and to analyze the impacts of different initial populations on the optimization result. The result shows that GA is competent for the capture of CNOP in the context of the idealized model with parameterization ‘on-off’ switches in this study. Finally, the advantages and disadvantages of GA in capturing CNOP are analyzed in detail.展开更多
At present,equivalent water depth truncated mooring system optimization design is regarded as the priority of hybrid model testing for deep sea platforms,and will replace the full depth system test in the future.Compa...At present,equivalent water depth truncated mooring system optimization design is regarded as the priority of hybrid model testing for deep sea platforms,and will replace the full depth system test in the future.Compared with the full depth system,the working depth and span are smaller in the truncated one,and the other characteristics maintain more consistency as well.In this paper,an inner turret moored floating production storage & offloading system(FPSO) which works at a water depth of 320m,was selected to be a research example while the truncated water depth was 80m.Furthermore,an improved non-dominated sorting genetic algorithm(INSGA-II) was selected to optimally calculate the equivalent water depth truncated system,considering the stress condition of the total mooring system in both the horizontal and vertical directions,as well as the static characteristic similarity of the representative single mooring line.The results of numerical calculations indicate that the mathematical model is feasible,and the optimization method is fast and effective.展开更多
In order to balance the temporal-spatial distribution of urban traffic flow, a model is established for combined urban traffic signal control and traffic flow guidance. With consideration of the wide use of fixed sign...In order to balance the temporal-spatial distribution of urban traffic flow, a model is established for combined urban traffic signal control and traffic flow guidance. With consideration of the wide use of fixed signal control at intersections, traffic assignment under traffic flow guidance, and dynamic characteristics of urban traffic management, a tri-level programming model is presented. To reflect the impact of intersection delay on traffic assignment, the lower level model is set as a modified user equilibrium model. The middle level model, which contains several definitional constraints for different phase modes, is built for the traffic signal control optimization. To solve the problem of tide lane management, the upper level model is built up based on nonlinear 0-1 integer programming. A heuristic iterative optimization algorithm(HIOA) is set up to solve the tri-level programming model. The lower level model is solved by method of successive averages(MSA), the middle level model is solved by non-dominated sorting genetic algorithm II(NSGA II), and the upper level model is solved by genetic algorithm(GA). A case study is raised to show the efficiency and applicability of the proposed modelling and computing method.展开更多
Cracking furnace is the core device for ethylene production. In practice, multiple ethylene furnaces are usually run in parallel. The scheduling of the entire cracking furnace system has great significance when multip...Cracking furnace is the core device for ethylene production. In practice, multiple ethylene furnaces are usually run in parallel. The scheduling of the entire cracking furnace system has great significance when multiple feeds are simultaneously processed in multiple cracking furnaces with the changing of operating cost and yield of product. In this paper, given the requirements of both profit and energy saving in actual production process, a multi-objective optimization model contains two objectives, maximizing the average benefits and minimizing the average coking amount was proposed. The model can be abstracted as a multi-objective mixed integer non- linear programming problem. Considering the mixed integer decision variables of this multi-objective problem, an improved hybrid encoding non-dominated sorting genetic algorithm with mixed discrete variables (MDNSGA-II) is used to solve the Pareto optimal front of this model, the algorithm adopted crossover and muta- tion strategy with multi-operators, which overcomes the deficiency that normal genetic algorithm cannot handle the optimization problem with mixed variables. Finally, using an ethylene plant with multiple cracking furnaces as an example to illustrate the effectiveness of the scheduling results by comparing the optimization results of multi-objective and single objective model.展开更多
To promote the development of the intangible cultural heritage of the world, shadow play, many studies have focused on shadow puppet modeling and interaction. Most of the shadow puppet figures are still imaginary,spre...To promote the development of the intangible cultural heritage of the world, shadow play, many studies have focused on shadow puppet modeling and interaction. Most of the shadow puppet figures are still imaginary,spread by ancients, or carved and painted by shadow puppet artists, without consideration of real dimensions or the appearance of human bodies. This study proposes an algorithm to transform 3D human models to 2D puppet figures for shadow puppets, including automatic location of feature points, automatic segmentation of 3D models, automatic extraction of 2D contours, automatic clothes matching, and animation. Experiment proves that more realistic and attractive figures and animations of the shadow puppet can be generated in real time with this algorithm.展开更多
As the running speed of high-speed trains increases, aerodynamic drag becomes the key factor which limits the further increase of the running speed and energy consumption. Aerodynamic lift of the trailing car also bec...As the running speed of high-speed trains increases, aerodynamic drag becomes the key factor which limits the further increase of the running speed and energy consumption. Aerodynamic lift of the trailing car also becomes the key force which affects the amenity and safety of the train. In the present paper, a simplified CRH380A high-speed train with three carriages is chosen as the model in order to optimize aerodynamic drag of the total train and aerodynamic lift of the trailing car. A constrained mul- ti-objective optimization design of the aerodynamic head shape of high-speed trains based on adaptive non-dominated sorting genetic algorithm is also developed combining local function three-dimensional parametric approach and central Latin hypercube sampling method with maximin criteria based on the iterative local search algorithm. The results show that local function parametric approach can be well applied to optimal design of complex three-dimensional aerodynamic shape, and the adaptive non-dominated sorting genetic algorithm can be more accurate and efficient to find the Pareto front. After optimization the aerodynamic drag of the simplified train with three carriages is reduced by 3.2%, and the lift coefficient of the trailing car by 8.24%, the volume of the streamlined head by 2.16%; the aerodynamic drag of the real prototype CRH380A is reduced by 2.26%, lift coefficient of the trailing car by 19.67%. The variation of aerodynamic performance between the simplified train and the true train is mainly concentrated in the deformation region of the nose cone and tail cone. The optimization approach proposed in the present paper is simple yet efficient, and sheds lights on the constrained multi-objective engineering optimization design of aerodynamic shape of high-speed trains.展开更多
Although time series are frequently nonlinear in reality, people tend to use linear models to fit them under some assumptJLons unnecessarily in accordance with the truth, which unsurprisingly leads to unsatisfactory p...Although time series are frequently nonlinear in reality, people tend to use linear models to fit them under some assumptJLons unnecessarily in accordance with the truth, which unsurprisingly leads to unsatisfactory performance. This paper proposes a forecast method: Genetic programming based on least square method (GP-LSM). Inheriting the advantages of genetic algorithm (GA), without relying on the particular distribution of the data, this method can improve the prediction accuracy because of its ability of fitting nonlinear models, and raise the convergence speed benefitting from the least square method (LSM). In order to verify the vMidity of this method, the authors compare this method with seasonal auto regression integrated moving average (SARIMA) and back propagation artificial neural networks (BP-ANN). The results of empirical analysis show that forecast accuracy and direction prediction accuracy of GP-LSM are obviously better than those of the others.展开更多
文摘This paper describes an innovative, genetic algorithm based inverse model of nonlinear transducer. In the inverse modeling, using a genetic algorithm, the unknown coefficients of the model are estimated accurately. The simulation results indicate that this technique provides greater flexibility and suitability than the existing methods. It is very easy to modify the nonlinear transducer on line. Thus the method improves the transducer's accuracy. With the help of genetic algorithm (GA), the model coefficients' training are less likely to be trapped in local minima than traditional gradient based search algorithms.
文摘To improve the performance of fuel cells, the operating temperature of molten carbonate fuel cell (MCFC) stack should be controlled within a specified range. In this paper, with the RBF neural network’s ability of identifying complex nonlinear systems, a neural network identification model of MCFC stack is developed based on the sampled input-output data. Also, a novel online fuzzy control procedure for the temperature of MCFC stack is developed based on the fuzzy genetic algorithm (FGA). Parameters and rules of the fuzzy controller are optimized. With the neural network identification model, simulation of MCFC stack control is carried out. Validity of the model and the superior performance of the fuzzy controller are demonstrated.
文摘Hereditary non-polyposis colorectal carcinoma (HNPCC) is an autosomal dominant disorder associated with colorectal and endometrial cancer and a range of other tumor types. Germline mutations in the DNA mismatch repair (MMR) genes, particularly MLH1, MEH2, and MEH5, underlie this disorder. The vast majority of these HNPCC-associated mutations have been proven, or assumed, given the family history of cancer, to be transmitted through several generations. To the best of our knowledge, only a single case of a de novo germline MMR gene mutation (in MEH2) has been reported till now. Here, we report a patient with a de novo mutation in MLH1. We identified a MLH1 Q701X truncating mutation in the blood lymphocytes of a male who had been diagnosed with rectal cancer at the age of 35. His family history of cancer was negative for the first- and second-degree relatives. The mutation could not be detected in the patient's parents and sibling and paternity was confirmed with a set of highly polymorphic markers. Non-penetrance and small family size is the common explanation of verified negative family histories of cancer in patients with a germline MMR gene mutation. However, in addition to some cases explained by non-paternity, de novo germline mutations should be considered as a possible explanation as well. As guidelines that stress not to restrict MMR gene mutation testing to patients with a positive family history are more widely introduced, more cases of de novo MMR gene germline mutations may be revealed.
基金Project(50925727) supported by the National Fund for Distinguish Young Scholars of ChinaProject(60876022) supported by the National Natural Science Foundation of China+1 种基金Project(2010FJ4141) supported by Hunan Provincial Science and Technology Foundation,ChinaProject supported by the Fund of the Key Construction Academic Subject (Optics) of Hunan Province,China
文摘A model of correcting the nonlinear error of photoelectric displacement sensor was established based on the least square support vector machine.The parameters of the correcting nonlinear model,such as penalty factor and kernel parameter,were optimized by chaos genetic algorithm.And the nonlinear correction of photoelectric displacement sensor based on least square support vector machine was applied.The application results reveal that error of photoelectric displacement sensor is less than 1.5%,which is rather satisfactory for nonlinear correction of photoelectric displacement sensor.
基金Application investigation of conditional nonlinear optimal perturbation in typhoon adaptive observation (40830955)
文摘In the typhoon adaptive observation based on conditional nonlinear optimal perturbation (CNOP), the ‘on-off’ switch caused by moist physical parameterization in prediction models prevents the conventional adjoint method from providing correct gradient during the optimization process. To address this problem, the capture of CNOP, when the "on-off" switches are included in models, is treated as non-smooth optimization in this study, and the genetic algorithm (GA) is introduced. After detailed algorithm procedures are formulated using an idealized model with parameterization "on-off" switches in the forcing term, the impacts of "on-off" switches on the capture of CNOP are analyzed, and three numerical experiments are conducted to check the effectiveness of GA in capturing CNOP and to analyze the impacts of different initial populations on the optimization result. The result shows that GA is competent for the capture of CNOP in the context of the idealized model with parameterization ‘on-off’ switches in this study. Finally, the advantages and disadvantages of GA in capturing CNOP are analyzed in detail.
基金Supported by the National Natural Science Foundation of China (Grant No. 10602055)Natural Science Foundation of Zhejiang Province (Grant No. Y6110243)
文摘At present,equivalent water depth truncated mooring system optimization design is regarded as the priority of hybrid model testing for deep sea platforms,and will replace the full depth system test in the future.Compared with the full depth system,the working depth and span are smaller in the truncated one,and the other characteristics maintain more consistency as well.In this paper,an inner turret moored floating production storage & offloading system(FPSO) which works at a water depth of 320m,was selected to be a research example while the truncated water depth was 80m.Furthermore,an improved non-dominated sorting genetic algorithm(INSGA-II) was selected to optimally calculate the equivalent water depth truncated system,considering the stress condition of the total mooring system in both the horizontal and vertical directions,as well as the static characteristic similarity of the representative single mooring line.The results of numerical calculations indicate that the mathematical model is feasible,and the optimization method is fast and effective.
基金Project(2014BAG01B0403)supported by the High-Tech Research and Development Program of China
文摘In order to balance the temporal-spatial distribution of urban traffic flow, a model is established for combined urban traffic signal control and traffic flow guidance. With consideration of the wide use of fixed signal control at intersections, traffic assignment under traffic flow guidance, and dynamic characteristics of urban traffic management, a tri-level programming model is presented. To reflect the impact of intersection delay on traffic assignment, the lower level model is set as a modified user equilibrium model. The middle level model, which contains several definitional constraints for different phase modes, is built for the traffic signal control optimization. To solve the problem of tide lane management, the upper level model is built up based on nonlinear 0-1 integer programming. A heuristic iterative optimization algorithm(HIOA) is set up to solve the tri-level programming model. The lower level model is solved by method of successive averages(MSA), the middle level model is solved by non-dominated sorting genetic algorithm II(NSGA II), and the upper level model is solved by genetic algorithm(GA). A case study is raised to show the efficiency and applicability of the proposed modelling and computing method.
基金Supported by the National Natural Science Foundation of China(21276078)"Shu Guang"project of Shanghai Municipal Education Commission,973 Program of China(2012CB720500)the Shanghai Science and Technology Program(13QH1401200)
文摘Cracking furnace is the core device for ethylene production. In practice, multiple ethylene furnaces are usually run in parallel. The scheduling of the entire cracking furnace system has great significance when multiple feeds are simultaneously processed in multiple cracking furnaces with the changing of operating cost and yield of product. In this paper, given the requirements of both profit and energy saving in actual production process, a multi-objective optimization model contains two objectives, maximizing the average benefits and minimizing the average coking amount was proposed. The model can be abstracted as a multi-objective mixed integer non- linear programming problem. Considering the mixed integer decision variables of this multi-objective problem, an improved hybrid encoding non-dominated sorting genetic algorithm with mixed discrete variables (MDNSGA-II) is used to solve the Pareto optimal front of this model, the algorithm adopted crossover and muta- tion strategy with multi-operators, which overcomes the deficiency that normal genetic algorithm cannot handle the optimization problem with mixed variables. Finally, using an ethylene plant with multiple cracking furnaces as an example to illustrate the effectiveness of the scheduling results by comparing the optimization results of multi-objective and single objective model.
基金supported by the National Natural Science Foundation of China(Nos.61103100,61303137,and 51205059)the Natural Science Foundation of Zhejiang Province,China(Nos.Y13F020143 and LY13F030002)the Fundamental Research Funds for the Central Universities,China(No.2014QNA5009)
文摘To promote the development of the intangible cultural heritage of the world, shadow play, many studies have focused on shadow puppet modeling and interaction. Most of the shadow puppet figures are still imaginary,spread by ancients, or carved and painted by shadow puppet artists, without consideration of real dimensions or the appearance of human bodies. This study proposes an algorithm to transform 3D human models to 2D puppet figures for shadow puppets, including automatic location of feature points, automatic segmentation of 3D models, automatic extraction of 2D contours, automatic clothes matching, and animation. Experiment proves that more realistic and attractive figures and animations of the shadow puppet can be generated in real time with this algorithm.
基金supported by the Major State Basic Research Development Program of China ("973" Program) (Grant No. 2011CB711100) National Key Technology R&D Program (Grant No. 2009BAQG12A03)
文摘As the running speed of high-speed trains increases, aerodynamic drag becomes the key factor which limits the further increase of the running speed and energy consumption. Aerodynamic lift of the trailing car also becomes the key force which affects the amenity and safety of the train. In the present paper, a simplified CRH380A high-speed train with three carriages is chosen as the model in order to optimize aerodynamic drag of the total train and aerodynamic lift of the trailing car. A constrained mul- ti-objective optimization design of the aerodynamic head shape of high-speed trains based on adaptive non-dominated sorting genetic algorithm is also developed combining local function three-dimensional parametric approach and central Latin hypercube sampling method with maximin criteria based on the iterative local search algorithm. The results show that local function parametric approach can be well applied to optimal design of complex three-dimensional aerodynamic shape, and the adaptive non-dominated sorting genetic algorithm can be more accurate and efficient to find the Pareto front. After optimization the aerodynamic drag of the simplified train with three carriages is reduced by 3.2%, and the lift coefficient of the trailing car by 8.24%, the volume of the streamlined head by 2.16%; the aerodynamic drag of the real prototype CRH380A is reduced by 2.26%, lift coefficient of the trailing car by 19.67%. The variation of aerodynamic performance between the simplified train and the true train is mainly concentrated in the deformation region of the nose cone and tail cone. The optimization approach proposed in the present paper is simple yet efficient, and sheds lights on the constrained multi-objective engineering optimization design of aerodynamic shape of high-speed trains.
基金supported by the National Natural Science Foundation of China under Grant Nos.71171011 and 91224001Program for New Century Excellent Talents in University(NCET-12-0756)
文摘Although time series are frequently nonlinear in reality, people tend to use linear models to fit them under some assumptJLons unnecessarily in accordance with the truth, which unsurprisingly leads to unsatisfactory performance. This paper proposes a forecast method: Genetic programming based on least square method (GP-LSM). Inheriting the advantages of genetic algorithm (GA), without relying on the particular distribution of the data, this method can improve the prediction accuracy because of its ability of fitting nonlinear models, and raise the convergence speed benefitting from the least square method (LSM). In order to verify the vMidity of this method, the authors compare this method with seasonal auto regression integrated moving average (SARIMA) and back propagation artificial neural networks (BP-ANN). The results of empirical analysis show that forecast accuracy and direction prediction accuracy of GP-LSM are obviously better than those of the others.