Objectives: To quantitatively assess improvement in acne scarring after a ser ies of nonablative laser treatments and to determine efficacy at 1- , 3- , and 6-month follow-up after treatment. Design: Before-after tria...Objectives: To quantitatively assess improvement in acne scarring after a ser ies of nonablative laser treatments and to determine efficacy at 1- , 3- , and 6-month follow-up after treatment. Design: Before-after trial of consecut ively selected patients. Setting: Private practice at the Laser and Skin Surgery Center of New York, New York. Patients: Eleven patients with mild to moderate a trophic acne scarring were treated. Interventions: A 3- dimensional optical pro filing imaging system was used to assess skin topography before, during, and aft er treatment. Patients were treated with a 1064- nm Q-switched Nd:YAG laser a nd reassessed after 3 treatment sessions and at 1, 3, and 6 months after the fif th treatment session. Main Outcome Measures: The skin roughness analysis was qua ntified at baseline and at each follow-up interval. Pain, erythema, and petech iae formation were assessed on 3-point scales. Results: At midtreatment (1 mon th after the third treatment session), an 8.9% improvement in roughness analys is was seen. This improvement increased to 23.3% , 31.6% , and 39.2% at 1, 3 , and 6 months after the fifth treatment, respectively. Patients reported mild t o moderate pain with treatment. The only adverse effects noted were transient er ythema and mild pinpoint petechiae. Conclusions: Treatment with the nonablative 1064-nm Q-switched Nd:YAG laser results in significant quantitative improvem ents in skin topography in patients with mild to moderate atrophic acne scars. C ontinued incremental improvements were noted at 1- , 3- , and 6-month follow -up, indicating ongoing dermal collagen remodeling after the treatment.展开更多
We report the case of a 4 year- old boy with Parry- Romberg syndrome who ha d intractable seizures, progressive cerebral hemisphere atrophy, and fatal brain stem involvement.
文摘Objectives: To quantitatively assess improvement in acne scarring after a ser ies of nonablative laser treatments and to determine efficacy at 1- , 3- , and 6-month follow-up after treatment. Design: Before-after trial of consecut ively selected patients. Setting: Private practice at the Laser and Skin Surgery Center of New York, New York. Patients: Eleven patients with mild to moderate a trophic acne scarring were treated. Interventions: A 3- dimensional optical pro filing imaging system was used to assess skin topography before, during, and aft er treatment. Patients were treated with a 1064- nm Q-switched Nd:YAG laser a nd reassessed after 3 treatment sessions and at 1, 3, and 6 months after the fif th treatment session. Main Outcome Measures: The skin roughness analysis was qua ntified at baseline and at each follow-up interval. Pain, erythema, and petech iae formation were assessed on 3-point scales. Results: At midtreatment (1 mon th after the third treatment session), an 8.9% improvement in roughness analys is was seen. This improvement increased to 23.3% , 31.6% , and 39.2% at 1, 3 , and 6 months after the fifth treatment, respectively. Patients reported mild t o moderate pain with treatment. The only adverse effects noted were transient er ythema and mild pinpoint petechiae. Conclusions: Treatment with the nonablative 1064-nm Q-switched Nd:YAG laser results in significant quantitative improvem ents in skin topography in patients with mild to moderate atrophic acne scars. C ontinued incremental improvements were noted at 1- , 3- , and 6-month follow -up, indicating ongoing dermal collagen remodeling after the treatment.
文摘We report the case of a 4 year- old boy with Parry- Romberg syndrome who ha d intractable seizures, progressive cerebral hemisphere atrophy, and fatal brain stem involvement.
