患者男,21岁,因癫痫发作入院。智力尚正常,5岁时无明显诱因出现头皮肿物并逐年增大变硬,13岁时始出现面部丘疹、甲周肿物、口唇部结节,以及前胸及后腰部皮肤隆起,无痒痛。5岁后时有癫痫发作,每日2次,于当地医院进行对症治疗。既往有高...患者男,21岁,因癫痫发作入院。智力尚正常,5岁时无明显诱因出现头皮肿物并逐年增大变硬,13岁时始出现面部丘疹、甲周肿物、口唇部结节,以及前胸及后腰部皮肤隆起,无痒痛。5岁后时有癫痫发作,每日2次,于当地医院进行对症治疗。既往有高血压病史,血压150/90 mm Hg(1 mm Hg=0.133 kPa)。体格检查:于右肋缘下触及一直径约10 cm肿物,无压痛;头颅右侧顶部见一直径约8 cm肿物突出于头皮表面,表面不光滑,质韧;双侧面颊可见粟粒状淡粉色丘疹密集对称分布,质较硬。展开更多
A9-year-old female developed facial papules and pustules since fo ur years . Clinically, perioral dermatitis was suspected. Different topical therapy regim ens and systemic antibiotics had been unsuccessful and a skin...A9-year-old female developed facial papules and pustules since fo ur years . Clinically, perioral dermatitis was suspected. Different topical therapy regim ens and systemic antibiotics had been unsuccessful and a skin biopsy showed gran ulomatous (lupoid) rosacea. Only systemic antibiotic treatment with minocyclin l ed to healing of the skin lesions. While granulomatous rosacea-like dermatitis is more frequently diagnosed in adults, it is only rarely encountered in childr en where, in most of the cases, it represents a therapeutic challenge.展开更多
文摘患者男,21岁,因癫痫发作入院。智力尚正常,5岁时无明显诱因出现头皮肿物并逐年增大变硬,13岁时始出现面部丘疹、甲周肿物、口唇部结节,以及前胸及后腰部皮肤隆起,无痒痛。5岁后时有癫痫发作,每日2次,于当地医院进行对症治疗。既往有高血压病史,血压150/90 mm Hg(1 mm Hg=0.133 kPa)。体格检查:于右肋缘下触及一直径约10 cm肿物,无压痛;头颅右侧顶部见一直径约8 cm肿物突出于头皮表面,表面不光滑,质韧;双侧面颊可见粟粒状淡粉色丘疹密集对称分布,质较硬。
文摘A9-year-old female developed facial papules and pustules since fo ur years . Clinically, perioral dermatitis was suspected. Different topical therapy regim ens and systemic antibiotics had been unsuccessful and a skin biopsy showed gran ulomatous (lupoid) rosacea. Only systemic antibiotic treatment with minocyclin l ed to healing of the skin lesions. While granulomatous rosacea-like dermatitis is more frequently diagnosed in adults, it is only rarely encountered in childr en where, in most of the cases, it represents a therapeutic challenge.
