冷冻球囊导管消融术联合左心耳封堵术一站式治疗心房颤动23例术中护理

心房颤动(房颤)是临床上最常见的快速心律失常之一,冷冻球囊导管消融术原理是通过低温制冷从而造成靶组织细胞冻伤、坏死,破坏房颤心律失常基质来达到治疗效果^([1]).血栓栓塞是房颤患者的主要并发症之一,非瓣膜性房颤患者中大约有90%血栓来源于左心耳^([2]).因此,可通过封堵左心耳来预防房颤患者血栓栓塞.

2型糖尿病的自白

我叫2型糖尿病,医学专家给我下的定义是:由于胰岛素分泌绝对或相对不足,或靶组织细胞对胰岛素敏感性降低,而引起血糖、蛋白、脂肪等一系列代谢紊乱,临床以高血糖为主要特征的一组疾病。我有个哥哥叫1型糖尿病,不过,他现在发病率不高,在我的家族中还不到5%;我还有个弟弟叫糖代谢减退,有人称之为糖尿病后备军。

Prevention of Autoimmune Diabetes by Pentoxifylline is Associated with Target Tissue Modulation of Cytokines and the Expression of Fas-FasL

The effect of Pentoxifylline (PTX) on type 1 diabetes was investigated by means of the studies on the expressions of cytokine mRNA in pancreas and the Fas-FasL on islet cells of NOD mice. NOD mice were treated with PTX from 4-6?wk, and then from 8-12?wk. After treatment, it was found that the incidence of diabetes in NOD mice at ages of 30?wk was reduced to 25% in group of mice treated with PTX, in comparison to 73.3% in case of mice injected with PBS, and the degree of insulitis in the PTX treated mice was lower than that of the PBS injected mice. RT-PCR analysis revealed down-regulatory effect on the expressions of IFN-γ and TNF-α mRNA in PTX treated mice, but there was no any effect on the expression of IL-10. As to the expression of Fas, there was marked decrease in the mean cytoplasmic integral optical density (IOD) in PTX treated mice, but there was little difference between PTX and PBS groups in the expression of FasL. These results indicated that PTX could prevent the development of diabetes in NOD mice, which might be related to the regulation of Th1/Th2 imbalance and the decreased expression of Fas in islet cells.

超重肥胖与血压血糖关系的Logistic回归分析

随着经济的发展和人民生活水平的不断提高,超重、肥胖已成为影响人民健康的主要公共卫生问题。为进一步探索超重和肥胖对健康的影响,现对舟山普陀渔区2004年心脑血管病危险因素整群抽样调查的有关资料进行汇总分析,重点探讨超重、肥胖与高血压、高血糖的关系。

2型糖尿病的自白

我叫2型糖尿病,医学家给我下的定义:由于胰岛素分泌绝对或相对不足,或靶组织细胞对胰岛素敏感性降低或两者共同作用,而引起血糖、蛋白、脂肪等-系列代谢紊乱,临床,上以高血糖为主要特征的一组疾病。我有个哥哥叫1型糖尿病,不过,它现在发病率不高,在我的家族中还不到5%;我还有个弟弟叫糖代谢减退,有人誉之为糖尿病后备军。