城轨车辆接插件预制作及工装设计

随着城轨车辆市场需求的日益增长以及客户需求的多样化,对主机公司的产能及生产效率提出了更高的需求。客室接插件制作工序作为城轨车辆工位节拍化生产的重要工序,越来越成为进一步提升生产效率的瓶颈工序。提出将部分客室接插件制作工序提前,减少车上作业工序,并且设计了专用配套工装,在实际项目中证明可以有效提高生产效率。

预成正轴簧的设计与应用

预成正轴簧的设计与应用汉口铁路医院部口腔正崎科罗晓冰近年来，固定正畸矫治技术已越来越受到口腔正畸医生的关注，此项技术在临床应用上亦得到推广，随着门诊患者比重的上升，许多环节制约了医生工作效率的提高。如何缩短治疗、就诊时间，已引起广大正畸医生的重视，而...

提高换流站预埋套管安装工艺

为确保工程预埋套管施工的质量,针对该工程特点,进一步提高预埋套管的安装验收合格率,提高预埋套管的安装工艺质量,减少过程中的返工率。通过分析以往工程中出现的预埋套管的问题,分析导致问题的原因,排除非主要因素,找出主要影响因素,采取有效对策,大幅提高了套管预埋的合格率,预埋管的合格率由之前工程的85.7%,提高到了95.7%,同时减少了该分项工程消缺造成的人工、材料浪费,间接的节省了消缺的费用成本。

Eclipse公司发布EclipseSuite V3.0

Eclipse Suite软件发布一个符合900软件版权要求的标准的CD和DVD著作和预母盘制作系统。该软件包括对CD和DVD的母盘信号进行分析、纠错和校正功能．在过去的应用中该软件以其的可靠性和友好的用户界面获得了用户的好评。

Improved Disturbance Observer (DOB) Based Advanced Feedback Control for Optimal Operation of a Mineral Grinding Process

Advanced feedback control for optimal operation of mineral grinding process is usually based on the model predictive control (MPC) dynamic optimization. Since the MPC does not handle disturbances directly by controller design, it cannot achieve satisfactory effects in controlling complex grinding processes in the presence of strong disturbances and large uncertainties. In this paper, an improved disturbance observer (DOB) based MPC advanced feedback control is proposed to control the multivariable grinding operation. The improved DOB is based on the optimal achievable H 2 performance and can deal with disturbance observation for the nonminimum-phase delay systems. In this DOB-MPC advanced feedback control, the higher-level optimizer computes the optimal operation points by maximize the profit function and passes them to the MPC level. The MPC acts as a presetting controller and is employed to generate proper pre-setpoint for the lower-level basic feedback control system. The DOB acts as a compensator and improves the operation performance by dynamically compensating the setpoints for the basic control system according to the observed various disturbances and plant uncertainties. Several simulations are performed to demonstrate the proposed control method for grinding process operation.

Prevention of peritoneal adhesions:A promising role for gene therapy

Adhesions are the most frequent complication of abdominopelvic surgery,yet the extent of the problem,and its serious consequences,has not been adequately recognized.Adhesions evolved as a life-saving mecha-nism to limit the spread of intraperitoneal inflammatory conditions.Three different pathophysiological mechanisms can independently trigger adhesion formation.Mesothelial cell injury and loss during operations,tissue hypoxia and inflammation each promotes adhesion formation separately,and potentiate the effect of each other.Studies have repeatedly demonstrated that interruption of a single pathway does not completely prevent adhesion formation.This review summarizes the pathogenesis of adhesion formation and the results of single gene therapy interventions.It explores the prom-ising role of combinatorial gene therapy and vector modif ications for the prevention of adhesion formation in order to stimulate new ideas and encourage rapid advancements in this field.

ISCHEMIC PRECONDITIONING RELIEVES ISCHEMIA/REPERFUSION INJURY OF HIPPOCAMPUS NEURONS IN RAT BY INHIBITING p53 AND BAX EXPRESSIONS

Objective To examine whether ischemic preconditioning (IPC) can protect neuron against delayed death in CA1 subfield of hippocampus following reperfusion of a lethal ischemia in rats, and explore the role of p53 and bax in this process. Methods We examined the effect of IPC on delayed neuron death, neuron apoptosis, expressions of p53 and bax gene in the CA1 area of hippocampus in the rats using HE staining, flow cytometry, RT-PCR, and immunohistochemistry technique. Results IPC enhanced the quantity of survival cells in the CA1 region of hippocampus (216±9 cells/0.72 mm2 vs. 30±5 cells/0.72 mm2, P<0.01), decreased the percentages of apoptotic neurons of hippocampus caused by ischemia/reperfusion (2.06%±0.21% vs. 4.27%±0.08%, P<0.01), and weakened the expressions of p53 and bax gene of hippocampus compared with ischemia/reperfusion without IPC. Conclusion IPC can protect the neurons in the CA1 region of hippocampus against apoptosis caused by ische- mia/reperfusion, and this process may be related to the reduced expressions of p53 and bax.

A Composite Model Predictive Control Strategy for Furnaces

Tube furnaces are essential and primary energy intensive facilities in petrochemical plants. Operational optimization of furnaces could not only help to improve product quality but also benefit to reduce energy consumption and exhaust emission. Inspired by this idea, this paper presents a composite model predictive control(CMPC)strategy, which, taking advantage of distributed model predictive control architectures, combines tracking nonlinear model predictive control and economic nonlinear model predictive control metrics to keep process running smoothly and optimize operational conditions. The controllers connected with two kinds of communication networks are easy to organize and maintain, and stable to process interferences. A fast solution algorithm combining interior point solvers and Newton's method is accommodated to the CMPC realization, with reasonable CPU computing time and suitable online applications. Simulation for industrial case demonstrates that the proposed approach can ensure stable operations of furnaces, improve heat efficiency, and reduce the emission effectively.

Time-delayed bilateral teleoperation using wave variable with prediction in three channel control architecture

This paper proposes a novel method for incorporating wave domain prediction in a three-channel(3CH)architecture,which is the optimal architecture from a transparency point of view,to overcome the poor transparency problem of using the wave variable method in a time-delay teleoperation system.A 3CH teleoperation control architecture is established by selecting parameters of the 4CH architecture sensibly for the system without force sensor in the master side.The communication channel is divided into a two-port model by combining force and velocity information reasonably to extend the wave variable method to a 3CH architecture.Then the I/O signal of the two-port model is transformed into wave variable.A predictor is added to the wave domain of the master side to further improve the transparency of the system,and a regulator is designed to ensure the passivity of the predictor.Experimental results show that the proposed method can guarantee stability and improve the transparency of the teleoperation system with time-delay.

The Connection Between Slavery and Prophecy as It Relates tothe American Nation in the Writings of the Adventist PioneersDuring the Antebellum Period

The period between 1850 and 1865 was a period of major social upheavals in American society; the major issue was the slavery. This period also witnessed the birth and organization of the Sabbatarian Adventism, a pre-millennial Christian movement distinguished by an emphasis on the Seventh-day Sabbath and a special understanding of Bible prophecies. Most Adventist pioneers vehemently opposed slavery, although not always on the same ground as their Christian counterparts. Aided by their peculiar understanding of Bible prophecy, the early Adventists identified America with apocalyptical end-time power, slavery being the key attribute of the ＂beast that looks like a lamb but speaks like a dragon＂ from Revelation 13：11. This article investigates the development of Adventist connection between slavery, America and Bible prophecy.

An International Journalism Model of Professionalism in News Production： The Concepts and the Measurements

This study aimed to contribute in establishing an international journalism model of professionalism in the production of the news. The main purpose is to explore the degree to which this model predicts the professional values in the media content. In particular, this model was tested on the content of a leading news organization in the Middle East, AI Jazeera, to identify whether or not AI Jazeera reflected professional values in news production or other non-professional values. A total of 592 news stories--234 from AJE and 358 from AJA--published from January I, 2014, to April 30, 2014, were analyzed. The findings of this study indicate that AI Jazeera reflects professional values to a substantial degree. The professional values were reflected highly and nearly two thirds of the stories had professional values in the content. The chi square tests shows there are frequency/percentage differences, but overall the patterns are similar, with no statistically significant differences in the AJA and AlE. Scholarly implications, future studies and limitations were presented in this study.

Biochemical Mechanisms of Therapeutic and Prophylactic Effects of Bioflavonoids

In the present study to investigate the biochemical mechanisms of therapeutic and prophylactic action of bioflavonoids, carried out a comparative evaluation of antioxidant and antiproteinase properties of certain bioflavonoids standards in vitro. Therapeutic and prophylactic efficacy of individual bioflavonoids as well as herbal medicines with bioflavonoids, was examined at an experimental pathology （toxic hepatitis, dental caries, periodontitis, stomatitis, dysbiosis, diabetes Types 1 and 2, gastric ulcer, osteopenia） in Wistar line rats. Condition of organs and tissues was assessed by biochemical markers of inflammation, antioxidant and antimicrobial defense systems of animals. Research has shown the ability ofbioflavonoids in varying degrees inhibit the formation of superoxide anion radicals and malondialdehyde, recover free radicals, bind ions of Fe2＋, inhibiting the activity of proteases, such as leukocyte elastase. Established partially competitive type of trypsin and elastase activity inhibition by bioflavonoids. Was revealed a positive effect of bioflavonoids in experimental pathology on animals. Therapeutic and prophylactic effects of bioflavonoids, in our opinion, are realized through a strong antioxidant and antiprotease properties of these compounds.

AN ACCURATE PREDICTION MODEL FOR COMPUTATIONAL OVERHEADS OF SECURITY MECHANISMS IN WIRELESS SENSOR NETWORKS

In Wireless Sensor Networks (WSNs), it is necessary to predict computational overheads of security mechanisms without final implementations to provide guidelines for system design. This paper presents an accurate and flexible model to predict overheads of these mechanisms. This model is based on overheads of basic operations frequently used in cryptography algorithms, which are essential elements of security mechanisms. Several popular cryptography algorithms and security mechanisms are evaluated using this model. According to simulation results, relative prediction errors are less than 7% for most cryptography algorithms and security mechanisms.

Inhibitive effect on apoptosis in splenic lymphocytes of mice pretreated with Lingzhi (GanodermaLucidum) spores

OBJECTIVE： To investigate how the pretreatment of mice with Ganoderma spores affected the apop- tosis of their splenic lymphocytes induced by dexa- methasone after 19 days treatment. METHODS： Sixty Kunming mice were randomly di- vided into six groups： blank control groupdrenched with normal saline; a drug control group drenched with 150 mg/mL Ganoderma spores; a model group treated with saline; a low dose group with S0 mg/mL Ganoderma spores; a moderate dose group with 100 mg/mL Ganoderma spores; and a high dose group with 150 mg/mL Ganoderma spores. The effect of Ganoderma spores on apoptosis in spleen lymphocytes was analyzed. All groups were treated for 19 days. On day 20, the model group and the 3 treatment groups were intraperitoneally injected dexamethasone to induce apoptosis. Splenic index and apoptosis indes were employed to measure cell apoptosis RESULTS： The results showed that Ganoderma spores reduced the splenic index to different de- grees in each group and the best effect was seen in the high dose group （P〈0.05）. Terminal dexynucleo- tidyl transferase （TdT）-mediated 2＇-Deoxyuridine 5＇-Triphosphate nick end labeling staining revealed that the apoptotic index in all groups administered Ganoderma spores differed significantly from the model group, and a dose-response was observed. Flow cytometric analysis indicated that spleen lym- phocyte apoptosis in the model group was exten- sive. Each dose of Ganoderma spores inhibited dexamethasone-induced apoptosis in spleen lym- phocytes, and a dose-response was observed as well. The highest dose of Ganoderma spores de- creased Malondialdehyde content in serum in- duced by dexamethasone （P〈0.05）. CONCLUSION： The findings imply that the pretreat- ment of the mice with Ganoderma spores could re- duce the apoptosis rate induced by dexametha- sone in their splenic lymphocytes.

Inhibitive effect on phagocytosis of Candida albicans induced by pretreatment with quercetin via actin cytoskeleton interference

OBJECTIVE： To investigate the anti-inflammatory effect of pretreatment with quercetin on macro- phages after Candida albicans infection. METHODS： RAW 264.7 macrophages were used as a target cell line. Cell viability after treatment with quercetin at different time points was detected by Carboxyfluorescein diacetate, succinimidyl ester. Phagocytic function of macrophages was deter- mined by a fluorometric assay. Cytokine tumor ne- crosis factor a （TNF-a） production was measured by enzyme-linked immunosorbent assay. F-actin cy- toskeleton of L929 cells was stained by Alexa Fluor 488-phalloidin. RESULTS： Pretreatment with quercetin decreasedcell viability only at the highest concentration of 37 μg/mL 2, 24, and 48 h after the treatment. The phagocytic efficiency of macrophages pretreated with quercetin was significantly decreased in a time- and dose-dependent manner. F-actin label- ing showed that the actin cytoskeleton of the cells started to break down 2 h after treatment. More- over, it notably inhibited cytokine TNF-a produc- tion after Candida albicans infection. CONCLUSION： Pretreatment with quercetin in- duced an anti-inflammatory effect against Candida albicans infection in macrophages.

A modified predictive control strategy of three-phase grid-connected converters with optimized action time sequence

Due to the excellent dynamic performance,the Finite Control Set Model Predictive Control has been widely used in various types of converters.However,when Finite Control Set Model Predictive Control is adopted,the switching frequency of converters varies significantly with system operating conditions.Consequently,constant-frequency predictive control strategy has been proposed.Two active voltage vectors and a zero voltage vector are selected within each sampling period.The action time sequence is then calculated.Due to the unsymmetrical distribution of current variation rates around zero,the calculated value of the voltage-vector action time will turn up negative.According to common sense,the voltage-vector action time is greater than or equal to zero.The action time is normally forced to zero whenever a negative value is predicted,resulting in the control failure and performance deterioration.To solve this problem,this paper proposes modified strategy.The modified strategy examines the action time calculated out.When negative action time comes out,the modified strategy reselects the active voltage vector accordingly,instead of forcing the action time to be zero.Optimized action time sequence is further determined by minimizing the cost function.The effectiveness of the modified strategy is clearly verified by experimental tests,and analytical remarks are all founded in practical results.