人工流产综合症的预防临床研究

人工流产是计划生育失败后的补救措施，常规是在无镇痛措施下进行。孕妇在术中容易发生心动过缓、心律不齐、大汗淋漓、面色苍白、恶心、呕吐、胸闷、甚至出现血压下降、昏厥、抽搐等症状，称为人工流产综合症．作者对本院两年发生人工流产综合症的情况进行分析，制定了相应的护理预防措施，取得了较好的临床效果，现报告如下。

蛭龙胶囊在缺血性卒中二级预防中的作用

目的:观察蛭龙胶囊在缺血性卒中二级预防中的作用。方法:将238例本院门诊及住院的缺血性卒中患者按照有、无阿司匹林禁忌症分为两组。治疗组118例给予蛭龙胶囊,2粒/次,2次/d,口服;对照组120例给予肠溶阿司匹林片,100 mg/次,1次/d,口服。两组均以半年为1个疗程,治疗1个疗程。结果:治疗组治疗后血液总胆固醇、三酰甘油与对照组对比,差别有统计学意义(P<0.01);治疗组治疗后凝血酶原时间、活化部分凝血活酶时间与对照组对比,差别有统计学意义(P<0.05或P<0.01);治疗期间,治疗组复发4例,对照组复发4例。结论:蛭龙胶囊可以降低血脂,改善凝血功能,在缺血性卒中二级预防中能够达到与阿司匹林同样的功效,尤其对于临床对抗血小板聚集有明显禁忌症的患者,在缺血性卒中的二级预防中发挥了可以替代阿司匹林的作用,在缺血性卒中二级预防中应用前景广阔。

Study on the preventive effects of different drugs on reflux esophagitis in rats

Objective: To observe the damage of mixed reflux to the rat esophageal mucosa, and investigate the preventive effects of cisapride, nabumetone and hydrotalcite on the damaged esophageal mucosa. Methods: Three hundred sixty-eight Sprague-Dawley rats were treated as esophagoduodenostomy and divided into four groups in random. Group Y: operation + saline as positive controls; Group P: operation + cisapride; Group R: operation + nabumetone; Group D: operation + hydrotalcite. Different drugs were perfused in the 1 st week after operation. The lesions of esophageal mucosa were observed in the 5th, 9th, 13th, 17th, 22nd, 28th, 35th and 40th week respectively, and evaluated the preventive effects of these drugs. Results: The lesions of esophageal mucosa in group Y were more severe than other three groups in different time (P ＜ 0.05), and the incidence of Barrett's esophagus(BE), severe atypical hyperplasia and esophageal adenocarcinoma (EAC) in group Y were higher than others. After 22 weeks, the lesions in group P were more severe than group R and D, and there were obvious differences in different time ( P ＜ 0.05); but the incidence of BE, severe atypical hyperplasia and EAC in group P had no significant difference with group R and group D( P ＞ 0.05). Conclusion: BE, severe atypical hyperplasia and EAC could occur because of severe reflux esophagitis for a long term. Cisapride, nabumetone and hydrotalcite could reduce mucosa injury in reflux esophagitis and resist the development of BE, severe atypical hyperplasia and EAC.In addition, the curative effects of nabumetone and hydrotalcite were better than cisapride.

髋臼骨折手术治疗入路选择与并发症的防治

为探讨髋臼骨折手术治疗的入路选择与并发症的关系及防治措施，对62例手术治疗的髋臼骨折患者的临床资料进行了回顾性总结。结果表明选择合适的手术入路是提高髋臼骨折治疗效果的先决条件，最佳的手术时机为伤后4—7天内，而术前准备充分，术中减少组织剥离及创伤，争取髋臼关节面的解剖复位，以及内固定的合理放置，良好的创口冲洗与充分引流，合理应用抗生素和中药辩证施治，积极的进行功能康复训练等，对防治髋臼骨折术后常见并发症的发生有重要意义。