椎动脉型颈椎病（cervical spondylosis of arterial,CSA）是由于颈椎退行性病变、颈椎小关节紊乱、颈部软组织损伤及炎症等因素刺激和压迫椎动脉或颈交感神经,导致椎基底动脉有效血容量减少,引起脑部供血不足而出现以头晕、恶心、呕吐...椎动脉型颈椎病（cervical spondylosis of arterial,CSA）是由于颈椎退行性病变、颈椎小关节紊乱、颈部软组织损伤及炎症等因素刺激和压迫椎动脉或颈交感神经,导致椎基底动脉有效血容量减少,引起脑部供血不足而出现以头晕、恶心、呕吐及颈部不适为主症的病症。针灸治疗椎动脉颈椎病有较好的疗效。现将针灸治疗CSA研究进展综述如下。展开更多
Objective Cervical spinal cord stimulation （SCS） has been found to augment cerebral blood flow （CBF） in a number of animal models. However, the effective use of SCS is hampered by a lack of understanding of its me...Objective Cervical spinal cord stimulation （SCS） has been found to augment cerebral blood flow （CBF） in a number of animal models. However, the effective use of SCS is hampered by a lack of understanding of its mechanism（s） of action. In this paper, we focus on the sympathetic and parasympathetic effects of SCS on CBF. Method SpragueDawley rats were selected for the experimental series. The animals were divided into 5 groups to underwent SCS and laser Doppler flowmeter （LDF） recordings. Control group, the animal underwent SCS and LDF recordings without any surgery of the nerve fibers and ganglia. V 1 group, the animal underwent bilateral resection of the nasociliary and post-ganglionic parasympathetic nerve fibbers. SCG group, the animal underwent bilateral resection of supper cervical ganglion. V 1 ＋ SCG group, the animal underwent both surgeries as V1- and SCG-group animals did. Sham group, the animal underwent the carotid manipulation with blunt-tipped forceps as well as the dissection of nasociliary and post-ganglionic parasympathetic nerve fibers around the ethmoidal foramen, but without cutting any nerves. Results During the SCS, the LDF was no statistical difference between the V 1 or SCG group and the control group. Yet, the effects of SCS on CBF are completely abolished in V1＋ SCG group. Conclusions Surgical interruption of both the parasympathetic and sympathetic pathways has the contradict effect on SCS-induced CBF augmentation.展开更多
文摘椎动脉型颈椎病（cervical spondylosis of arterial,CSA）是由于颈椎退行性病变、颈椎小关节紊乱、颈部软组织损伤及炎症等因素刺激和压迫椎动脉或颈交感神经,导致椎基底动脉有效血容量减少,引起脑部供血不足而出现以头晕、恶心、呕吐及颈部不适为主症的病症。针灸治疗椎动脉颈椎病有较好的疗效。现将针灸治疗CSA研究进展综述如下。
文摘Objective Cervical spinal cord stimulation （SCS） has been found to augment cerebral blood flow （CBF） in a number of animal models. However, the effective use of SCS is hampered by a lack of understanding of its mechanism（s） of action. In this paper, we focus on the sympathetic and parasympathetic effects of SCS on CBF. Method SpragueDawley rats were selected for the experimental series. The animals were divided into 5 groups to underwent SCS and laser Doppler flowmeter （LDF） recordings. Control group, the animal underwent SCS and LDF recordings without any surgery of the nerve fibers and ganglia. V 1 group, the animal underwent bilateral resection of the nasociliary and post-ganglionic parasympathetic nerve fibbers. SCG group, the animal underwent bilateral resection of supper cervical ganglion. V 1 ＋ SCG group, the animal underwent both surgeries as V1- and SCG-group animals did. Sham group, the animal underwent the carotid manipulation with blunt-tipped forceps as well as the dissection of nasociliary and post-ganglionic parasympathetic nerve fibers around the ethmoidal foramen, but without cutting any nerves. Results During the SCS, the LDF was no statistical difference between the V 1 or SCG group and the control group. Yet, the effects of SCS on CBF are completely abolished in V1＋ SCG group. Conclusions Surgical interruption of both the parasympathetic and sympathetic pathways has the contradict effect on SCS-induced CBF augmentation.
