你希望寻找一种最经济的方式来联接远程节点吗?可看一看SymplexCommunications Corp.网际工作设备中的新型Direct Route产品系列。DirectRoute是租用线路路由器的替代产品,它为多节点提供高带宽、低价格的联接。 Direct Route家族中共...你希望寻找一种最经济的方式来联接远程节点吗?可看一看SymplexCommunications Corp.网际工作设备中的新型Direct Route产品系列。DirectRoute是租用线路路由器的替代产品,它为多节点提供高带宽、低价格的联接。 Direct Route家族中共有三位成员:DR1,DR2和DR5.我们来看一下$2,999的DR1,它是为小中型分支事务所设计的。DR1包括一个以太端口和四个ISDN基本速率接口(BRI)端口。由于一条BRI线路包含两条分离的64Kbps数据通道。展开更多
In our recent work [Phys. Chem. Chem. Phys. 11, 9149 （2009）], a molecular-mechanics force field-based amidc-Ⅰ vibration frequency map （MM-map） for peptides and proteins was constructed. In this work, the temperat...In our recent work [Phys. Chem. Chem. Phys. 11, 9149 （2009）], a molecular-mechanics force field-based amidc-Ⅰ vibration frequency map （MM-map） for peptides and proteins was constructed. In this work, the temperature dependence of the MM-map is examined based on high-temperature molecular dynamics simulations and infrared （IR） experiments. It is shown that the 298-K map works for up to 500-K molecular dynamics trajectories, which reasonably reproduces the 88 ℃ experimental IR results. Linear IR spectra are also simulated for two tripeptides containing natural and unnatural amino acid residues, and the results are in reasonable agreement with experiment. The results suggest the MM-map can be used to obtain the temperature-dependent amide-Ⅰ local mode frequencies and their distributions for peptide oligomers, which is useful in particular for understanding the IR signatures of the thermally unfolded species.展开更多
文摘你希望寻找一种最经济的方式来联接远程节点吗?可看一看SymplexCommunications Corp.网际工作设备中的新型Direct Route产品系列。DirectRoute是租用线路路由器的替代产品,它为多节点提供高带宽、低价格的联接。 Direct Route家族中共有三位成员:DR1,DR2和DR5.我们来看一下$2,999的DR1,它是为小中型分支事务所设计的。DR1包括一个以太端口和四个ISDN基本速率接口(BRI)端口。由于一条BRI线路包含两条分离的64Kbps数据通道。
基金This work was supported by the National Natural Science Foundation of China （No.30870591）, the National Basic Research Program of China （No.2007CB815205） and the Chinese Academy of Sciences （Hundred Talent Fund）. Chen Han thanks Dr. Kai-cong Cai for helpful discussions.
文摘In our recent work [Phys. Chem. Chem. Phys. 11, 9149 （2009）], a molecular-mechanics force field-based amidc-Ⅰ vibration frequency map （MM-map） for peptides and proteins was constructed. In this work, the temperature dependence of the MM-map is examined based on high-temperature molecular dynamics simulations and infrared （IR） experiments. It is shown that the 298-K map works for up to 500-K molecular dynamics trajectories, which reasonably reproduces the 88 ℃ experimental IR results. Linear IR spectra are also simulated for two tripeptides containing natural and unnatural amino acid residues, and the results are in reasonable agreement with experiment. The results suggest the MM-map can be used to obtain the temperature-dependent amide-Ⅰ local mode frequencies and their distributions for peptide oligomers, which is useful in particular for understanding the IR signatures of the thermally unfolded species.
