Nickel nanoparticles as an eco-friendly adsorbent was biosynthesized using Ocimum sanctum leaf extract. The physiochemical properties of green synthesized nickel nanoparticles(Ni Gs) were characterized by UV–Vis spec...Nickel nanoparticles as an eco-friendly adsorbent was biosynthesized using Ocimum sanctum leaf extract. The physiochemical properties of green synthesized nickel nanoparticles(Ni Gs) were characterized by UV–Vis spectroscopy(UV–Vis), Fourier Transform Infrared Spectroscopy(FTIR), X-ray diffraction(XRD), Scanning Electron Microscope(SEM) and Transmission Electron Microscope(TEM). Ni Gs were used as adsorbent for the removal of dyes such as crystal violet(CV), eosin Y(EY), orange II(OR) and anionic pollutant nitrate(NO3-), sulfate(SO42-) from aqueous solution. Adsorption capacity of Ni Gs was examined in batch modes at different p H, contact time, Ni G dosage, initial dye and pollutant concentration. The adsorption process was p H dependent and the adsorption capacity increased with increase in contact time and with that of Ni G dosage, whereas the adsorption capacity decreased at higher concentrations of dyes and pollutants. Maximum percentage removal of dyes and pollutants were observed at 40, 20,30, 10 and 10 mg·L-1initial concentration of CV, EY, OR, NO3-and SO42-respectively. The maximum adsorption capacities in Langmuir isotherm were found to be 0.454, 0.615, 0.273, 0.795 and 0.645 mg·g-1at p H 8, 3, 3, 7and 7 for CV, EY, OR, NO3-and SO42-respectively. The higher coef ficients of correlation in Langmuir isotherm suggested monolayer adsorption. The mean energies(E), 2.23, 3.53, 2.50, 5.00 and 3.16 k J·mol-1for CV, EY, OR, NO3-and SO42-respectively, calculated from the Dubinin–Radushkevich isotherm showed physical adsorption of adsorbate onto Ni Gs. Adsorption kinetics data was better fitted to pseudo-second-order kinetics with R2 N 0.870 for all dyes and pollutants. Ni Gs were found to be an effective adsorbent for the removal of dyes and pollutants from aqueous solution and can be applied to treat textile and tannery ef fluents.展开更多
We have developed aggregation-induced emission （AIE） dye loaded polymer nanoparticles with deep-red emission for siRNA delivery to pancreatic cancer cells. Two US Food and Drug Administration （FDA） approved surfac...We have developed aggregation-induced emission （AIE） dye loaded polymer nanoparticles with deep-red emission for siRNA delivery to pancreatic cancer cells. Two US Food and Drug Administration （FDA） approved surfactant polymers, Pluronics F127 and PEGylated phospholipid, were used to prepare the dye-loaded nanoparticle formulations and they can be used as nanovectors for gene silencing of mutant K-ras in pancreatic cancer cells. The successful transfection of siRNA by the developed nanovectors was confirmed by the fluorescent imaging and quantified through flow cytometry. Quantitative real time polymerase chain reaction （PCR） indicates that the expression of the mutant K-ras oncogene from the MiaPaCa-2 pancreatic cancer cells has been successfully suppressed. More importantly, our in vivo toxicity study has revealed that both the nanoparticle formulations are highly biocompatible in BALC/c mice. Overall, our results suggest that the AIE dye-loaded polymer nanoparticle formulations developed here are suitable for gene delivery and have high potential applications in translational medicine research.展开更多
Ternary Ⅰ–Ⅲ–Ⅵquantum dots（QDs） of chalcopyrite semiconductors exhibit excellent optical properties in solar cells. In this study, ternary chalcopyrite CuGaS2nanocrystals（2–5 nm） were one-pot anchored on TiO2...Ternary Ⅰ–Ⅲ–Ⅵquantum dots（QDs） of chalcopyrite semiconductors exhibit excellent optical properties in solar cells. In this study, ternary chalcopyrite CuGaS2nanocrystals（2–5 nm） were one-pot anchored on TiO2nanoparticles（TiO2@CGS） without any long ligand. The solar cell with TiO2@CuGaS2/N719 has a power conversion efficiency of7.4%, which is 23% higher than that of monosensitized dye solar cell. Anchoring CuGaS2 QDs on semiconductor nanoparticles to form QDs/dye co-sensitized solar cells is a promising and feasible approach to enhance light absorption,charge carrier generation as well as to facilitate electron injection comparing to conventional mono-dye sensitized solar cells.展开更多
文摘Nickel nanoparticles as an eco-friendly adsorbent was biosynthesized using Ocimum sanctum leaf extract. The physiochemical properties of green synthesized nickel nanoparticles(Ni Gs) were characterized by UV–Vis spectroscopy(UV–Vis), Fourier Transform Infrared Spectroscopy(FTIR), X-ray diffraction(XRD), Scanning Electron Microscope(SEM) and Transmission Electron Microscope(TEM). Ni Gs were used as adsorbent for the removal of dyes such as crystal violet(CV), eosin Y(EY), orange II(OR) and anionic pollutant nitrate(NO3-), sulfate(SO42-) from aqueous solution. Adsorption capacity of Ni Gs was examined in batch modes at different p H, contact time, Ni G dosage, initial dye and pollutant concentration. The adsorption process was p H dependent and the adsorption capacity increased with increase in contact time and with that of Ni G dosage, whereas the adsorption capacity decreased at higher concentrations of dyes and pollutants. Maximum percentage removal of dyes and pollutants were observed at 40, 20,30, 10 and 10 mg·L-1initial concentration of CV, EY, OR, NO3-and SO42-respectively. The maximum adsorption capacities in Langmuir isotherm were found to be 0.454, 0.615, 0.273, 0.795 and 0.645 mg·g-1at p H 8, 3, 3, 7and 7 for CV, EY, OR, NO3-and SO42-respectively. The higher coef ficients of correlation in Langmuir isotherm suggested monolayer adsorption. The mean energies(E), 2.23, 3.53, 2.50, 5.00 and 3.16 k J·mol-1for CV, EY, OR, NO3-and SO42-respectively, calculated from the Dubinin–Radushkevich isotherm showed physical adsorption of adsorbate onto Ni Gs. Adsorption kinetics data was better fitted to pseudo-second-order kinetics with R2 N 0.870 for all dyes and pollutants. Ni Gs were found to be an effective adsorbent for the removal of dyes and pollutants from aqueous solution and can be applied to treat textile and tannery ef fluents.
基金This work was supported by the National Natural Science Foundation of China （NSFC） （61107017, 81301318）, the Start-up grant （M4080141.040） from Nanyang Technological University, Tier 1 Academic Research Funds （M4010360.040 RG29/10） from Singapore Ministry of Education and partially from the Singapore Ministry of Education under a Tier 2 Research Grant MOE2010-T2-2-010 （4020020.040 ARC2/11） and the grant from the Shenzhen Basic Research Project （JC201005280391A）
文摘We have developed aggregation-induced emission （AIE） dye loaded polymer nanoparticles with deep-red emission for siRNA delivery to pancreatic cancer cells. Two US Food and Drug Administration （FDA） approved surfactant polymers, Pluronics F127 and PEGylated phospholipid, were used to prepare the dye-loaded nanoparticle formulations and they can be used as nanovectors for gene silencing of mutant K-ras in pancreatic cancer cells. The successful transfection of siRNA by the developed nanovectors was confirmed by the fluorescent imaging and quantified through flow cytometry. Quantitative real time polymerase chain reaction （PCR） indicates that the expression of the mutant K-ras oncogene from the MiaPaCa-2 pancreatic cancer cells has been successfully suppressed. More importantly, our in vivo toxicity study has revealed that both the nanoparticle formulations are highly biocompatible in BALC/c mice. Overall, our results suggest that the AIE dye-loaded polymer nanoparticle formulations developed here are suitable for gene delivery and have high potential applications in translational medicine research.
基金the financial support from the National Key Research and Development Program of China(2016YFA0201001)the National Natural Science Foundation of China(11627801,51102172 and 11772207)+7 种基金Science and Technology Plan of Shenzhen City(JCYJ20160331191436180)the Leading Talents of Guangdong Province Program(2016LJ06C372)the Natural ScienceFoundation for Outstanding Young Researcher in Hebei Province(E2016210093)the Key Program of Educational Commission of Hebei Province of China(ZD2016022)the Youth Top-notch Talents Supporting Plan of Hebei Provincethe Graduate Innovation Foundation of Shijiazhuang Tiedao UniversityHebei Provincial Key Laboratory of Traffic Engineering materialsHebei Key Discipline Construction Project
文摘Ternary Ⅰ–Ⅲ–Ⅵquantum dots（QDs） of chalcopyrite semiconductors exhibit excellent optical properties in solar cells. In this study, ternary chalcopyrite CuGaS2nanocrystals（2–5 nm） were one-pot anchored on TiO2nanoparticles（TiO2@CGS） without any long ligand. The solar cell with TiO2@CuGaS2/N719 has a power conversion efficiency of7.4%, which is 23% higher than that of monosensitized dye solar cell. Anchoring CuGaS2 QDs on semiconductor nanoparticles to form QDs/dye co-sensitized solar cells is a promising and feasible approach to enhance light absorption,charge carrier generation as well as to facilitate electron injection comparing to conventional mono-dye sensitized solar cells.
