With in vitro spin labeling electron spin resonance (ESR) spectroscopy, we have studied the effects of Bu Yang Huan Wu (BYHW) decoction and its effective constituents such as astragaloside IV ferulic acid, chua...With in vitro spin labeling electron spin resonance (ESR) spectroscopy, we have studied the effects of Bu Yang Huan Wu (BYHW) decoction and its effective constituents such as astragaloside IV ferulic acid, chuanxiongzine, rutin, chlorogenic acid, 9,10 dimethoxy pterocarpane 7 O β D glucoside, calycosin, formononetin, calycosin 7 O glucoside, paeoniflorin, paeonal and quercein on the cell membrane fluidity of a rat brain which was modeled after the dual cervical arteries were intercepted and released for realizing an ischemia reperfusion injury which was selected as a brain stroke model. Our results indicated that the cell membrane fluidity in the model group decreased approximately 8% compared with the control group, and after brain cells were incubatied with species, the membrane fluidity could be recovered closely to the control level depending on the BYHW decoction and its different constituents. As the membrane fluidity is a very sensitive biological index which reflectsd the cell status, our method will be useful to study the molecular mechanism of tradition Chinese medicine (TCM) and its combination recipe.展开更多
The seasonal and interannual variations of the vertical distribution of the Kuroshio velocity and its formative mechanism were studied by analyzing the Global Ocean Reanalysis Simulation 2 （GLORYS2） dataset in the P...The seasonal and interannual variations of the vertical distribution of the Kuroshio velocity and its formative mechanism were studied by analyzing the Global Ocean Reanalysis Simulation 2 （GLORYS2） dataset in the Pollution Nagasaki （PN） section （126.0°E-128.2°, at depths less than 1000 m）. The results indicated that： 1） the maximum transport in the PN section occurs in summer, followed by spring, and the minimum transport occurs in fall and winter; the maximum velocities are located at the subsurface in both winter and summer and velocities are relatively larger and at a shallower depth in summer; and the velocity core is located at the surface in spring and fall. The isopycnic line has a clear depression around the Kuroshio axis in winter. The depth of maximum velocity and the zero horizontal density gradients both exhibit substantial seasonal and interannual variations, and the interannual variations are larger. 2） The distributions of velocity and density are in accordance with the therma~ wind relation. Although Kuroshio transport is determined by the large-scale wind field and mesoscale motion in the Pacific Ocean; local heat flux and thermohaline circulation influence the density field, modify the vertical structure of the Kuroshio velocity, and adjust the allocation of water fluxes and nutrients transport. 3） Shelf-water offshore transport into the Kuroshio upper layer induced by southwest monsoons might contribute to the maximum velocity up to the surface in summer. Nonlinear and nongeostrophic processes are not considered in the present study, and the thermal wind relation accounts for part of the vertical structure of the Kuroshio velocity.展开更多
This study, based on the literature, stresses the effectiveness of internal control systems for the prevention, to a reasonable extent, of fraudulent practices that cause resource loss in business. In this context, th...This study, based on the literature, stresses the effectiveness of internal control systems for the prevention, to a reasonable extent, of fraudulent practices that cause resource loss in business. In this context, the key concepts related to fraud and internal control systems are presented first. After the introduction, the relation between fraud and internal control systems is elaborated, and the method for establishing an effective internal control system which is needed to detect and prevent fraud is explained. As for the conclusion, the study connects the effectiveness of the internal control system with the effectiveness of the elements which compose the system, and provides some suggestions for increasing the efficacy of the elements which compose the system, such as control environment, risk analysis, information-communication, control activities, and monitoring.展开更多
文摘With in vitro spin labeling electron spin resonance (ESR) spectroscopy, we have studied the effects of Bu Yang Huan Wu (BYHW) decoction and its effective constituents such as astragaloside IV ferulic acid, chuanxiongzine, rutin, chlorogenic acid, 9,10 dimethoxy pterocarpane 7 O β D glucoside, calycosin, formononetin, calycosin 7 O glucoside, paeoniflorin, paeonal and quercein on the cell membrane fluidity of a rat brain which was modeled after the dual cervical arteries were intercepted and released for realizing an ischemia reperfusion injury which was selected as a brain stroke model. Our results indicated that the cell membrane fluidity in the model group decreased approximately 8% compared with the control group, and after brain cells were incubatied with species, the membrane fluidity could be recovered closely to the control level depending on the BYHW decoction and its different constituents. As the membrane fluidity is a very sensitive biological index which reflectsd the cell status, our method will be useful to study the molecular mechanism of tradition Chinese medicine (TCM) and its combination recipe.
文摘The seasonal and interannual variations of the vertical distribution of the Kuroshio velocity and its formative mechanism were studied by analyzing the Global Ocean Reanalysis Simulation 2 （GLORYS2） dataset in the Pollution Nagasaki （PN） section （126.0°E-128.2°, at depths less than 1000 m）. The results indicated that： 1） the maximum transport in the PN section occurs in summer, followed by spring, and the minimum transport occurs in fall and winter; the maximum velocities are located at the subsurface in both winter and summer and velocities are relatively larger and at a shallower depth in summer; and the velocity core is located at the surface in spring and fall. The isopycnic line has a clear depression around the Kuroshio axis in winter. The depth of maximum velocity and the zero horizontal density gradients both exhibit substantial seasonal and interannual variations, and the interannual variations are larger. 2） The distributions of velocity and density are in accordance with the therma~ wind relation. Although Kuroshio transport is determined by the large-scale wind field and mesoscale motion in the Pacific Ocean; local heat flux and thermohaline circulation influence the density field, modify the vertical structure of the Kuroshio velocity, and adjust the allocation of water fluxes and nutrients transport. 3） Shelf-water offshore transport into the Kuroshio upper layer induced by southwest monsoons might contribute to the maximum velocity up to the surface in summer. Nonlinear and nongeostrophic processes are not considered in the present study, and the thermal wind relation accounts for part of the vertical structure of the Kuroshio velocity.
文摘This study, based on the literature, stresses the effectiveness of internal control systems for the prevention, to a reasonable extent, of fraudulent practices that cause resource loss in business. In this context, the key concepts related to fraud and internal control systems are presented first. After the introduction, the relation between fraud and internal control systems is elaborated, and the method for establishing an effective internal control system which is needed to detect and prevent fraud is explained. As for the conclusion, the study connects the effectiveness of the internal control system with the effectiveness of the elements which compose the system, and provides some suggestions for increasing the efficacy of the elements which compose the system, such as control environment, risk analysis, information-communication, control activities, and monitoring.
