期刊文献+
共找到2篇文章
< 1 >
每页显示 20 50 100
释《王祯农书》词语四则 被引量:1
1
作者 丁建川 《山东农业大学学报(社会科学版)》 2018年第4期10-12,19,共4页
《王祯农书》中"风斤""望迷""""擿行"四词,《汉语大词典》等辞书或未收录,或有释义未当、未尽之处。"风斤"一词意为"锋利的斧头",源自《庄子·徐无鬼》"郢匠运斤... 《王祯农书》中"风斤""望迷""""擿行"四词,《汉语大词典》等辞书或未收录,或有释义未当、未尽之处。"风斤"一词意为"锋利的斧头",源自《庄子·徐无鬼》"郢匠运斤"故事,但《汉语大词典》释为"尖厉的寒风",且未列典源出处;"望迷"义为"迷蒙",《汉语大词典》等未收该词;《汉语大词典》无""字,应为"络"的俗体字,音义相同而形异,在《王祯农书》中义为"缠绕、束缚";"擿行"义为"以足蹬动点地而行",《汉语大词典》等未收。 展开更多
关键词 《王祯农书》 风斤 望迷 [糹若] 擿行
下载PDF
Assessing the therapeutic impact of Qianjinba polysaccharide in a rheumatoid arthritis murine model
2
作者 Nan Zhang Zhimin Liu +3 位作者 Xuanmei Yang Shuang Li Yiwen Gao Haiguang Qin 《Journal of Chinese Pharmaceutical Sciences》 CAS 2024年第8期705-713,共9页
Qianjinba is primarily cultivated in the southern regions of China and finds extensive use in traditional Chinese medicine(TCM)for conditions such as rheumatism,arthralgia,and gynecological ailments.It has been offici... Qianjinba is primarily cultivated in the southern regions of China and finds extensive use in traditional Chinese medicine(TCM)for conditions such as rheumatism,arthralgia,and gynecological ailments.It has been officially recognized as a protected variety of TCM by the state.The aim of this study was to investigate the therapeutic potential of Qianjinba polysaccharide(QJBDT)in treating rheumatoid arthritis(RA)in mice,along with a preliminary exploration of its mechanisms for inhibiting RA in these animals.Kunming mice(KM)were randomly divided into several groups,including a normal group,a model group(LPS group),low-dose,medium-dose,and high-dose QJBDT groups,as well as a positive control group(TGP group),each consisting of 10 mice.To induce inflammation and create an RA model,type II collagen was injected into the right hind foot joint.Following a 7-day modeling period,various concentrations of QJBDT and the positive control drug total glycoside of peony were administered via gavage once a day for 21 consecutive days.Throughout the study,we monitored and recorded the mice's weight,measured foot swelling,and assessed the arthritis index on a weekly basis.We also conducted pathological examinations of joint tissues and analyzed the signal pathway of p38 mitogen-activated protein kinase(MAPK)as well as the protein expression of nuclear factor NF-κB in the mice’s right foot joint tissues.Additionally,we employed ELISA to detect the levels of interleukin-β(IL-β),IL-17,and tumor necrosis factor-α(TNF-α)in the mice’s serum.The results of this study revealed that QJBDT effectively reduced the degree of foot swelling and the arthritis index in collagen-induced arthritis mice while improving their weight loss(P<0.05).Furthermore,it alleviated the pathological damage observed in the mice’s joints.Notably,the expression of transcription factors p38 and NF-κB proteins was down-regulated(P<0.05),and the levels of inflammatory cytokines IL-β,IL-17,and TNF-αin the mice’s serum were decreased(P<0.05).In conclusion,this study demonstrated that polysaccharides could inhibit the expression of transcription factors p38 and NF-κB,reduce the production of inflammatory factors,and alleviate the progression of RA to a certain extent. 展开更多
关键词 Qianjinba polysaccharide Rheumatoid arthritis Inflammatory factors p38 Mitogen activated protein kinase signaling pathway NF-κB
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部