乌头汤治疗风湿痹症随机平行对照研究

[目的]观察乌头汤治疗风湿痹症疗效。[方法]使用随机平行对照方法,将98例门诊及住院患者按就诊顺序号法简单随机分为两组。对照组49例来氟米特,50mg/次,睡前口服,连服3d;后剂量变为10-20mg,1次/d。治疗组49例乌头汤（麻黄、黄芪、芍药各12g,甘草10g,制川乌9g;风湿阻络加清风藤、防风各20g,威灵仙15g;寒湿痹阻加干姜、桂枝各10g）,1剂/d,早晚餐后30min口服。连续治疗30d为1疗程。观测临床症状、ESR、RF、CRP、BPC、不良反应。治疗1疗程,判定疗效。[结果]治疗组痊愈23例,显效22例,无效4例,总有效率91.84%。对照组痊愈21例,显效16例,无效12例,总有效率75.51%。治疗组疗效优于对照组（P〈0.05）。症状积分治疗组改善优于对照组（P〈0.01）。血清指标两组均有改善（P〈0.01）,治疗组改善大部分优于对照组（P〈0.01）,小部分无较大差异（P〉0.05）。[结论]乌头汤治疗风湿痹症疗效满意,无严重不良反应,值得推广。

金实治疗类风湿关节炎经验

从类风湿关节炎（RA）的病因病机、辨证、遣方用药等方面,探讨金实教授诊治RA的学术思想和临床经验。金实教授认为RA的病理因素有风、寒、湿、热、痰、瘀之别,总病机是风湿痹络,故以祛风除湿通络为基本大法,自拟痹痛方为基础方,配合经方、时方,灵活变通,不拘一格,疗效可靠。

A DOUBLE BLIND OBSERVATION FOR THERAPEUTIC EFFECTS OF THE TONG LUO KAI BI TABLETS ON RHEUMATOID ARTHRITIS

The therapeutic effects of the Tong Luo Kai Bi Tablets [symbol: see text] in 120 patients with rheumatoid arthritis were observed in this clinical trial by the randomized double blind method. Both the observed group and the control group each had 60 patients. In the observed group treated with the Tong Luo Kai Bi Tablets, 1 case (1.7%) was cured clinically, 27 cases (45.0%) improved markedly, 26 cases (43.3%) improved, with a total effective rate of 90.0%. In the control group treated with Rheumatic Semen Strychni Tablets [symbol: see text], no case was cured, 16 cases (26.7%) improved markedly, 33 cases (55.0%) improved, with a total effective rate of 81.7%. Statistical data showed the Tong Luo Kai Bi Tablets had much better therapeutic effectiveness clinically than the Rheumatic Semen Strychni Tablets (P

卿仙止痛膏治疗腰肌劳损的Ⅲ期临床疗效观察

目的:评价卿仙止痛膏治疗腰肌劳损(风湿痹阻兼瘀血阻络)临床症状的有效性及安全性。方法:采用随机、双盲、安慰剂平行对照的方法将64例腰肌劳损患者随机分为卿仙止痛膏治疗组(治疗组)和安慰剂对照组(对照组),将膏药贴于患处,24h换药1次,每次2贴,7d后观察患者治疗前后的临床症状、体征的变化,检测安全性指标:生命体征、血尿便常规、肝肾功能、心电图、不良反应。结果:治疗组总有效率为76.60%,对照组总有效率37.5%,治疗组疗效明显优于对照组(P<0.05);并且治疗组治疗后的疼痛、重着积分较对照组治疗后明显下降(P<0.001),而治疗后腰膝酸软、转侧不利积分较对照组治疗后也明显下降(P<0.05)。结论:卿仙止痛膏治疗腰肌劳损疗效确切、安全。