Objective: The work is a comparative study between two modalities of radiation therapy, the aim of which is to compare 3D conformal radiation therapy (3D-CRT) and intensity modulated radiation therapy (IMRT) in t...Objective: The work is a comparative study between two modalities of radiation therapy, the aim of which is to compare 3D conformal radiation therapy (3D-CRT) and intensity modulated radiation therapy (IMRT) in treating posterior fossa boost in children with high risk medulloblastorna; dosimetrically evaluating and comparing both techniques as regard target coverage and doses to organs at risk (OAR). Methods: Twenty patients with high risk medulloblastoma were treated by 3D-CRT technique. A dosimetric comparison was done by performing two plans for the posterior fossa boost, 3D-CRT and IMRT plans, for the same patient using Eclipse planning system (version 8.6). Results: IMRT had a better conformity index compared to 3D-CRT plans (P value of 0.000). As for the dose homogeneity it was also better in the IMRT plans, yet it hasn't reached the statistical significant value. Also, doses received by the cochleae, brainstem and spinal cord were significantly less in the IMRT plans than those of 3D-CRT (P value 〈 0.05). Conclusion: IMRT technique was clearly able to improve conformity and homogeneity index, spare the cochleae, reduce dose to the brainstem and spinal cord in comparison to 3D- CRT technique.展开更多
A risk in the prices of fossil fuels is a major concern to importing countries of them. This study analyzes the risk of an increase in the cost for Japanese electric utility sector during the period 1978-2007 consider...A risk in the prices of fossil fuels is a major concern to importing countries of them. This study analyzes the risk of an increase in the cost for Japanese electric utility sector during the period 1978-2007 considering the uncertainty in the prices of fossil fuels. The mean-semivariance model, which uses an upper semivariance as an index of the risk, is adopted for the purpose. The result confirms that the semivariance is the better index of the risk than the variance. Furether, the semivariance is decomposed into two factors; the risk caused by price changes in an individual fossil fuel source and the risk caused by correlations among the changes in the prices of fossil fuel sources. The former has been kept at a low level as it appears to be easy to estimate, while the latter has not been maintained at the lowest level as it appears to be difficult to estimate. The Japanese electric utility sector followed the minimum-risk fossil fuel mix up until 2001, but discontinued the same post 2001.展开更多
文摘Objective: The work is a comparative study between two modalities of radiation therapy, the aim of which is to compare 3D conformal radiation therapy (3D-CRT) and intensity modulated radiation therapy (IMRT) in treating posterior fossa boost in children with high risk medulloblastorna; dosimetrically evaluating and comparing both techniques as regard target coverage and doses to organs at risk (OAR). Methods: Twenty patients with high risk medulloblastoma were treated by 3D-CRT technique. A dosimetric comparison was done by performing two plans for the posterior fossa boost, 3D-CRT and IMRT plans, for the same patient using Eclipse planning system (version 8.6). Results: IMRT had a better conformity index compared to 3D-CRT plans (P value of 0.000). As for the dose homogeneity it was also better in the IMRT plans, yet it hasn't reached the statistical significant value. Also, doses received by the cochleae, brainstem and spinal cord were significantly less in the IMRT plans than those of 3D-CRT (P value 〈 0.05). Conclusion: IMRT technique was clearly able to improve conformity and homogeneity index, spare the cochleae, reduce dose to the brainstem and spinal cord in comparison to 3D- CRT technique.
文摘A risk in the prices of fossil fuels is a major concern to importing countries of them. This study analyzes the risk of an increase in the cost for Japanese electric utility sector during the period 1978-2007 considering the uncertainty in the prices of fossil fuels. The mean-semivariance model, which uses an upper semivariance as an index of the risk, is adopted for the purpose. The result confirms that the semivariance is the better index of the risk than the variance. Furether, the semivariance is decomposed into two factors; the risk caused by price changes in an individual fossil fuel source and the risk caused by correlations among the changes in the prices of fossil fuel sources. The former has been kept at a low level as it appears to be easy to estimate, while the latter has not been maintained at the lowest level as it appears to be difficult to estimate. The Japanese electric utility sector followed the minimum-risk fossil fuel mix up until 2001, but discontinued the same post 2001.