AIM: To study the main environmental and lifestyle factors that account for the regional differences in esophageal cancer (EC) risk in low- and high-risk areas of Jiangsu Province, China. METHODS: Since 2003, a po...AIM: To study the main environmental and lifestyle factors that account for the regional differences in esophageal cancer (EC) risk in low- and high-risk areas of Jiangsu Province, China. METHODS: Since 2003, a population-based casecontrol study has been conducted simultaneously in lowrisk (Ganyu County) and high-risk (Dafeng County) areas of Jiangsu Province, China. Using identical protocols and pre-tested standardized questionnaire, following written informed consent, eligible subjects were inquired about their detail information on potential determinants of EC, including demographic information, socio-economic status, living conditions, disease history, family cancer history, smoking, alcohol drinking, dietary habits, frequency, amount of food intake, etc. Conditional logistic regression with maximum likelihood estimation was used to obtain Odds ratio (OR) and 95 % confidence interval (95% CI), after adjustment for potential confounders. RESULTS: In the preliminary analysis of the ongoing study, we recruited 291 pairs of cases and controls in Dafeng and 240 pairs of cases and controls in Ganyu, respectively. In both low-risk and high-risk areas, EC was inversely associated with socio-economic status, such as level of education, past economic status and body mass index. However, this disease was more frequent among those who had a family history of cancer or encountered misfortune in the past 10 years. EC was also more frequent among smokers, alcohol drinkers and fast eaters. Furthermore, there was a geographic variation of the associations between smoking, alcohol drinking and EC risk despite the similar prevalence of these risk factors in both low-risk and high-risk areas. The dose-response relationship of smoking and smoking related variables, such as age of the first smoking, duration and amount were apparent only in high-risk areas. On the contrary, a dose-response relationship on the effect of alcohol drinking on EC was observed only in low-risk areas. CONCLUSION: The environmental risk factors, together with genetic factors and gene-environmental interactions might be the main reason for this high-risk gradient in .liangsu Province, China.展开更多
AIM: To evaluate the impact of the diagnosis of hepatitis C infection on lifestyle habits such as smoking, drinking, sports activity and diet.METHODS: A self-administered, anonymous question-naire was offered to out-p...AIM: To evaluate the impact of the diagnosis of hepatitis C infection on lifestyle habits such as smoking, drinking, sports activity and diet.METHODS: A self-administered, anonymous question-naire was offered to out-patients with HCV infection consecutively attending three clinical centres in Italy.RESULTS: Of the 275 respondents, 62.2% (171) were male. Mean age was 51 (range 20-80) years. Overall, after the diagnosis of hepatitis C, 74.5% of drinkers had modified (giving up or reducing) alcohol consumption, 21.3% of smokers had modifi ed their habits and 32.3% of subjects who reported sports activity had either stopped or reduced frequency of activity or chose a less fatiguing sport. Sixty-four percent of the respondents reported having modified their diet, most of them on physician's advice. CONCLUSION: After the diagnosis of hepatitis C many patients correctly modif ied their alcohol consumption and a minority their smoking habits. The reason for reported changes in diet and physical activity needs further investigations.展开更多
Cowpea (Vigna unguiculata L. Walp.) and tomato (Lycopersicum esculentum L. Karst) are attacked by a wide range of insect pests worldwide. In many cases, pesticides are used to control the pests. In 2010 and 2011, ...Cowpea (Vigna unguiculata L. Walp.) and tomato (Lycopersicum esculentum L. Karst) are attacked by a wide range of insect pests worldwide. In many cases, pesticides are used to control the pests. In 2010 and 2011, we conducted field experiments to evaluate and compare the effectiveness of a biorational (Agroneem~) and conventional pesticide (imidacloprid or thiamethoxam) on insect pests of these crops. In the first year, two varieties of cowpea (Mississippi Silver and Pinkeye Purple Hull) and two of tomato (Mariana and German Johnson) were used; in the second year, the better performing of each group (Mississippi Silver and Mariana) were used for the study. A split-plot design with four replications in Year 1, and a randomized complete block design with six treatment combinations in Year 2. In the first year, both pesticide groups were applied following manufacturer's recommendation (10-14 d cycles); and in the second year, the application of the pesticides was driven by economic thresholds level (ETL) of insect pests. The most prevalent species of insects recorded in both crops were in the families: Chrysomelidae, Pentatomidae, Cicadellidae, Vespidae, Sarcophagidae, Thripidae and Sphingidae. In both years, the diversity of insects on cowpea was greater than on tomato and more insects were observed in the second year compared to the first, despite the absence of significant difference (P 〉 0.05) between varieties in the treated plots. The yield of cowpea and tomato was comparable in all sprayed plots.展开更多
基金Supported by Jiangsu Provincial Health Department No. RC 2003090
文摘AIM: To study the main environmental and lifestyle factors that account for the regional differences in esophageal cancer (EC) risk in low- and high-risk areas of Jiangsu Province, China. METHODS: Since 2003, a population-based casecontrol study has been conducted simultaneously in lowrisk (Ganyu County) and high-risk (Dafeng County) areas of Jiangsu Province, China. Using identical protocols and pre-tested standardized questionnaire, following written informed consent, eligible subjects were inquired about their detail information on potential determinants of EC, including demographic information, socio-economic status, living conditions, disease history, family cancer history, smoking, alcohol drinking, dietary habits, frequency, amount of food intake, etc. Conditional logistic regression with maximum likelihood estimation was used to obtain Odds ratio (OR) and 95 % confidence interval (95% CI), after adjustment for potential confounders. RESULTS: In the preliminary analysis of the ongoing study, we recruited 291 pairs of cases and controls in Dafeng and 240 pairs of cases and controls in Ganyu, respectively. In both low-risk and high-risk areas, EC was inversely associated with socio-economic status, such as level of education, past economic status and body mass index. However, this disease was more frequent among those who had a family history of cancer or encountered misfortune in the past 10 years. EC was also more frequent among smokers, alcohol drinkers and fast eaters. Furthermore, there was a geographic variation of the associations between smoking, alcohol drinking and EC risk despite the similar prevalence of these risk factors in both low-risk and high-risk areas. The dose-response relationship of smoking and smoking related variables, such as age of the first smoking, duration and amount were apparent only in high-risk areas. On the contrary, a dose-response relationship on the effect of alcohol drinking on EC was observed only in low-risk areas. CONCLUSION: The environmental risk factors, together with genetic factors and gene-environmental interactions might be the main reason for this high-risk gradient in .liangsu Province, China.
基金Supported by a grant from Minister of Health (Ricerca Corrente 2001), Linea 1
文摘AIM: To evaluate the impact of the diagnosis of hepatitis C infection on lifestyle habits such as smoking, drinking, sports activity and diet.METHODS: A self-administered, anonymous question-naire was offered to out-patients with HCV infection consecutively attending three clinical centres in Italy.RESULTS: Of the 275 respondents, 62.2% (171) were male. Mean age was 51 (range 20-80) years. Overall, after the diagnosis of hepatitis C, 74.5% of drinkers had modified (giving up or reducing) alcohol consumption, 21.3% of smokers had modifi ed their habits and 32.3% of subjects who reported sports activity had either stopped or reduced frequency of activity or chose a less fatiguing sport. Sixty-four percent of the respondents reported having modified their diet, most of them on physician's advice. CONCLUSION: After the diagnosis of hepatitis C many patients correctly modif ied their alcohol consumption and a minority their smoking habits. The reason for reported changes in diet and physical activity needs further investigations.
文摘Cowpea (Vigna unguiculata L. Walp.) and tomato (Lycopersicum esculentum L. Karst) are attacked by a wide range of insect pests worldwide. In many cases, pesticides are used to control the pests. In 2010 and 2011, we conducted field experiments to evaluate and compare the effectiveness of a biorational (Agroneem~) and conventional pesticide (imidacloprid or thiamethoxam) on insect pests of these crops. In the first year, two varieties of cowpea (Mississippi Silver and Pinkeye Purple Hull) and two of tomato (Mariana and German Johnson) were used; in the second year, the better performing of each group (Mississippi Silver and Mariana) were used for the study. A split-plot design with four replications in Year 1, and a randomized complete block design with six treatment combinations in Year 2. In the first year, both pesticide groups were applied following manufacturer's recommendation (10-14 d cycles); and in the second year, the application of the pesticides was driven by economic thresholds level (ETL) of insect pests. The most prevalent species of insects recorded in both crops were in the families: Chrysomelidae, Pentatomidae, Cicadellidae, Vespidae, Sarcophagidae, Thripidae and Sphingidae. In both years, the diversity of insects on cowpea was greater than on tomato and more insects were observed in the second year compared to the first, despite the absence of significant difference (P 〉 0.05) between varieties in the treated plots. The yield of cowpea and tomato was comparable in all sprayed plots.