[Objective] This research aimed to explore the enrichment of edible fungi to the DNJ in mulberry branches.[Method] Reversed phase high performance liquid chromatography（RP-HPLC） method was used to study the enrichme...[Objective] This research aimed to explore the enrichment of edible fungi to the DNJ in mulberry branches.[Method] Reversed phase high performance liquid chromatography（RP-HPLC） method was used to study the enrichment of 9 varieties of edible fungi to the I-deoxynojirimycin（DNJ） in mulberry branches.[Result] The test edible fungi all could not synthesize DNJ,but Auricularia auricular,Ganoderma lucidum and Hericium erinaceus had enrichment capability to DNJ,and the enrichment was higher in pileus than in stipe.With the increasing proportion of mulberry sawdust in cultivation materials,the contents of DNJ in Ganoderma lucidum and Hericium erinaceus had increased;when the proportion of mulberry sawdust had achieved 50%,the contents of DNJ in the pileus of Hericium erinaceus and Ganoderma lucidum reached the maximum,which were 0.070 4% and 0.047 2%,respectively;afterwards,the contents of DNJ in the pileus were reduced with the increasing proportion of mulberry sawdust;when the proportion of mulberry sawdust had achieved 80%,the contents of DNJ in the pileus of Hericium erinaceus and Ganoderma lucidum had decreased to 0.047 4% and 0.032 7%,respectively.[Conclusion] This study provided theoretical basis and reference for the development of edible fungi in mulberry branches with hypoglycemic effects.展开更多
AIM: To evaluate the effects of self-expanding metal stents (SEMS) in patients with malignant esophageal obstruction and to analyze their prognosis and complications. METHODS: Seventy-four metallic stents were placed ...AIM: To evaluate the effects of self-expanding metal stents (SEMS) in patients with malignant esophageal obstruction and to analyze their prognosis and complications. METHODS: Seventy-four metallic stents were placed under fluoroscopic guidance in 66 patients with esophageal obstruction secondary to carcinoma, of whom, 6 cases were complicated by fistula. RESULTS: After seventy-two stents were successfully used in 66 cases without any severe complications (technical successful rate was 97%), the dysphagia score improved from 3.3±0.6 to 0.8±0.5 (P<0.01), and life quality improved significantly in all these patients. All fistulae were sealed immediately after coated stents were inserted in the six patients. New stents were placed in two patients: the stent migrated more than 2 cm, in one patients and the stent slipped into stomach in the other. Minor bleeding was found only in 28 patients during the operation. Reobstruction was found in 12 patients, but was successfully cured under endoscopy. The survival rate was 78%, 57% and 11% for 6 mo, 1 year and 2 years respectively. CONCLUSION: Placement of SEMS is a simple, safe, quick and efficient surgical method for treating esophageal carcinoma obstruction. It may be used mainly as a palliative treatment of esophageal obstruction secondary to carcinoma.展开更多
基金Supported by Sichuan Provincial Finance Genetic Engineering Special Fund (2011JYGC-QNJJ-021)Excellent Papers Fund of Sichuan Academy of Agricultural Sciences (2011JYGC-LWJJ-07)+1 种基金Special Fund for Construction of Modern Agricultural Technology System (No.CARS-22)Sci-Tech SME Technology Innovation of Nanchong City (11c0061)~~
文摘[Objective] This research aimed to explore the enrichment of edible fungi to the DNJ in mulberry branches.[Method] Reversed phase high performance liquid chromatography（RP-HPLC） method was used to study the enrichment of 9 varieties of edible fungi to the I-deoxynojirimycin（DNJ） in mulberry branches.[Result] The test edible fungi all could not synthesize DNJ,but Auricularia auricular,Ganoderma lucidum and Hericium erinaceus had enrichment capability to DNJ,and the enrichment was higher in pileus than in stipe.With the increasing proportion of mulberry sawdust in cultivation materials,the contents of DNJ in Ganoderma lucidum and Hericium erinaceus had increased;when the proportion of mulberry sawdust had achieved 50%,the contents of DNJ in the pileus of Hericium erinaceus and Ganoderma lucidum reached the maximum,which were 0.070 4% and 0.047 2%,respectively;afterwards,the contents of DNJ in the pileus were reduced with the increasing proportion of mulberry sawdust;when the proportion of mulberry sawdust had achieved 80%,the contents of DNJ in the pileus of Hericium erinaceus and Ganoderma lucidum had decreased to 0.047 4% and 0.032 7%,respectively.[Conclusion] This study provided theoretical basis and reference for the development of edible fungi in mulberry branches with hypoglycemic effects.
基金Supported by the National Medical Science and Technology Foundation during the 9th Five-Year Plan Period, No. 969070304
文摘AIM: To evaluate the effects of self-expanding metal stents (SEMS) in patients with malignant esophageal obstruction and to analyze their prognosis and complications. METHODS: Seventy-four metallic stents were placed under fluoroscopic guidance in 66 patients with esophageal obstruction secondary to carcinoma, of whom, 6 cases were complicated by fistula. RESULTS: After seventy-two stents were successfully used in 66 cases without any severe complications (technical successful rate was 97%), the dysphagia score improved from 3.3±0.6 to 0.8±0.5 (P<0.01), and life quality improved significantly in all these patients. All fistulae were sealed immediately after coated stents were inserted in the six patients. New stents were placed in two patients: the stent migrated more than 2 cm, in one patients and the stent slipped into stomach in the other. Minor bleeding was found only in 28 patients during the operation. Reobstruction was found in 12 patients, but was successfully cured under endoscopy. The survival rate was 78%, 57% and 11% for 6 mo, 1 year and 2 years respectively. CONCLUSION: Placement of SEMS is a simple, safe, quick and efficient surgical method for treating esophageal carcinoma obstruction. It may be used mainly as a palliative treatment of esophageal obstruction secondary to carcinoma.
