消化道器质性病变可以通过病理学检查证实，并可接受医学技术得到对症治疗。然而，除了器质性疾病外，还有一些以烧心、吞咽异常、恶心、呕吐、腹胀、腹痛、腹泻、便秘以及食物或粪便传递障碍为症状的疾病，这些被称为功能性非器质性症...消化道器质性病变可以通过病理学检查证实，并可接受医学技术得到对症治疗。然而，除了器质性疾病外，还有一些以烧心、吞咽异常、恶心、呕吐、腹胀、腹痛、腹泻、便秘以及食物或粪便传递障碍为症状的疾病，这些被称为功能性非器质性症状的发病机制仍然不清楚，且不能得到合理有效的治疗，给患者、家庭及社会带来很大的影响。功能性食管病（functional disease of the esophagus，FDE）是指无病理基础的胃．食管反流、食管动力异常或无明显食管组织结构、代谢异常情况下出现烧心、吞咽困难、胸痛等慢性食管症状。临床上FDE发病率一直保持较高的水平，因缺乏有效的诊断方法，不能及时准确地排除食管组织学结构及生化异常等原因引起的临床症状，致使对FDE的诊治困难。近年来，随着现代医学的发展，尤其是临床使用内镜检查、食管腔内压力和pH监测、组织学分析、钡餐造影或核素检查、食管腔内反流液的生化分析等，人们对FDE的发病机制有了深入了解，对其临床治疗也有了很大突破。展开更多
Objective To observe the clinical efficacy of acupuncture plus medicine in treating laryngopharyngeal reflux due to liverqi stagnation and spleen deficiency.Methods A total of 70 patients were divided into a control g...Objective To observe the clinical efficacy of acupuncture plus medicine in treating laryngopharyngeal reflux due to liverqi stagnation and spleen deficiency.Methods A total of 70 patients were divided into a control group and an observation group by the random number table method,with 35 cases in each group.Both groups were treated with conventional medications,and the observation group was treated with additional acupuncture therapy.The reflux symptom index(RSI)and reflux finding score(RFS)were evaluated.Esophageal motility indicators such as lower esophageal sphincter pressure(LESP)and upper esophageal sphincter pressure(UESP),and salivary pepsin level were measured.The clinical efficacy was also compared.Results The total effective rate of the observation group was higher than that of the control group(P<0.05).After treatment,the RSI and RFS scores in both groups decreased significantly(all P<0.05),and the RSI and RFS scores in the observation group were significantly lower than those in the control group(both P<0.05).There were no significant changes in the LESP and UESP in the control group(both P>0.05),while LESP and UESP in the observation group increased significantly(both P<0.05),and higher than those in the control group(both P<0.05).The salivary pepsin levels in both groups decreased(both P<0.05),and the salivary pepsin level in the observation group was significantly lower than that in the control group(P<0.05).Conclusion Acupuncture plus medicine can improve symptoms and signs in patients with laryngopharyngeal reflux due to liver-qi stagnation and spleen deficiency,and regulate esophageal motility and salivary pepsin level.Its efficacy is more significant compared with medicine alone.展开更多
文摘消化道器质性病变可以通过病理学检查证实，并可接受医学技术得到对症治疗。然而，除了器质性疾病外，还有一些以烧心、吞咽异常、恶心、呕吐、腹胀、腹痛、腹泻、便秘以及食物或粪便传递障碍为症状的疾病，这些被称为功能性非器质性症状的发病机制仍然不清楚，且不能得到合理有效的治疗，给患者、家庭及社会带来很大的影响。功能性食管病（functional disease of the esophagus，FDE）是指无病理基础的胃．食管反流、食管动力异常或无明显食管组织结构、代谢异常情况下出现烧心、吞咽困难、胸痛等慢性食管症状。临床上FDE发病率一直保持较高的水平，因缺乏有效的诊断方法，不能及时准确地排除食管组织学结构及生化异常等原因引起的临床症状，致使对FDE的诊治困难。近年来，随着现代医学的发展，尤其是临床使用内镜检查、食管腔内压力和pH监测、组织学分析、钡餐造影或核素检查、食管腔内反流液的生化分析等，人们对FDE的发病机制有了深入了解，对其临床治疗也有了很大突破。
文摘Objective To observe the clinical efficacy of acupuncture plus medicine in treating laryngopharyngeal reflux due to liverqi stagnation and spleen deficiency.Methods A total of 70 patients were divided into a control group and an observation group by the random number table method,with 35 cases in each group.Both groups were treated with conventional medications,and the observation group was treated with additional acupuncture therapy.The reflux symptom index(RSI)and reflux finding score(RFS)were evaluated.Esophageal motility indicators such as lower esophageal sphincter pressure(LESP)and upper esophageal sphincter pressure(UESP),and salivary pepsin level were measured.The clinical efficacy was also compared.Results The total effective rate of the observation group was higher than that of the control group(P<0.05).After treatment,the RSI and RFS scores in both groups decreased significantly(all P<0.05),and the RSI and RFS scores in the observation group were significantly lower than those in the control group(both P<0.05).There were no significant changes in the LESP and UESP in the control group(both P>0.05),while LESP and UESP in the observation group increased significantly(both P<0.05),and higher than those in the control group(both P<0.05).The salivary pepsin levels in both groups decreased(both P<0.05),and the salivary pepsin level in the observation group was significantly lower than that in the control group(P<0.05).Conclusion Acupuncture plus medicine can improve symptoms and signs in patients with laryngopharyngeal reflux due to liver-qi stagnation and spleen deficiency,and regulate esophageal motility and salivary pepsin level.Its efficacy is more significant compared with medicine alone.
