康艾注射液辅助化疗治疗晚期食管癌肝转移患者临床观察

目的:观察康艾注射液辅助化疗治疗晚期食管癌肝转移患者的临床疗效。方法:将73例晚期食管癌肝转移患者分为观察组37例和对照组36例;对照组采用常规化疗方法,观察组在对照组治疗基础上静脉滴注康艾注射液。比较2组患者近期疗效以及血常规、肝、肾功能的变化。结果:总有效率观察组48.65%,对照组30.56%,2组比较,差异有显著性意义(P<0.05);2组患者治疗前后白细胞和谷丙转氨酶比较,差异均无显著性意义(P>0.05)。观察组治疗后血红蛋白升高,与治疗前比较,差异有显著性意义(P<0.05),明显高于对照组(P<0.05)。2组患者治疗前后尿素氮(BUN)、血肌酐(SCr)、内生肌酐清除率(CCr)水平比较,差异均无显著性意义(P>0.05),2组治疗后比较,差异也无显著性意义(P>0.05)。结论:康艾注射液能够提高晚期食管癌肝转移患者的近期临床疗效,提高患者血红蛋白的水平,对患者的肝功能和肾功能具有保护作用,使用安全,值得临床推广。

Multiple von Meyenburg complexes mimicking diffuse liver metastases from esophageal squamous cell carcinoma

Von Meyenburg complexes are benign liver lesions consisting of adenomatous bile duct proliferates. We present two patients suffering from esophageal cancer accompanied by the occurrence of yon Meyenburg complexes. Preoperative computerized tomography （CT） of the liver had not shown these lesions. In one of the patients, diffuse nodular manifestation was found in both liver lobes, mimicking diffuse hepatic metastases. Intraoperative frozen section revealed the benign nature of the lesions in both cases. The patients underwent esophageal resection without complications. To the best of our knowledge, the coincidence of von Meyenburg complexes and esophageal cancer has never been reported before. This uncommon entity should be taken into consideration as a differential diagnosis of liver lesions in malignancies. It underlines the importance of intraoperative frozen section for liver lesions of unknown origin.