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基于网络药理学探讨《时病论》春温首方治疗流行性感冒的作用机制 被引量:1
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作者 刘毅 贾跃进 《中国民间疗法》 2020年第20期15-18,共4页
目的:利用网络药理学方法分析《时病论》春温首方治疗流行性感冒的可行性和作用机制。方法:检索TCMSP数据库,获取方剂各药物活性成分及相关靶点,并匹配基因名;在GeneCards等数据库中检索疾病相关靶点,筛选药物-疾病交集靶点;使用Cytosca... 目的:利用网络药理学方法分析《时病论》春温首方治疗流行性感冒的可行性和作用机制。方法:检索TCMSP数据库,获取方剂各药物活性成分及相关靶点,并匹配基因名;在GeneCards等数据库中检索疾病相关靶点,筛选药物-疾病交集靶点;使用CytoscapeV3.6.0创建疾病-成分-靶点网络及蛋白互作关系核心网络;运用Metascape平台分别对交集靶点进行GO、KEGG通路富集分析;选择关键成分与流行性感冒相关靶点分子对接。结果:筛选出《时病论》春温首方治疗流行性感冒的关键成分:山柰酚、木犀草素等;核心靶点:CASP3、MAPK3等。主要生物过程:细胞因子介导的信号通路、调节细胞因子的产生等;主要通路:AGE-RAGE信号通路、HIF-1信号通路等;分子对接显示关键成分均可与肺炎相关靶点稳定结合。结论:初步获得《时病论》春温首方通过抗病毒、抗炎、调节免疫治疗流行性感冒的作用机制,为该方的临床应用和进一步研究提供理论参考。 展开更多
关键词 网络药理学 流行性感冒 时病论 春温首方 作用机制 分子机制
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汉代龙首方身铜器的类型与用途 被引量:5
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作者 苏奎 《华夏考古》 CSSCI 北大核心 2017年第4期93-104,共12页
在汉代铜器当中,有一种龙首方身、扁形带刺的器物。宋代以来,有很多学者对其用途进行过推测,但是绝大多数的观点都难以令人信服。为避免著录伪作的影响,本文主要围绕考古出土的龙首方身铜器进行考察。首先从类型分析入手,然后再重新认... 在汉代铜器当中,有一种龙首方身、扁形带刺的器物。宋代以来,有很多学者对其用途进行过推测,但是绝大多数的观点都难以令人信服。为避免著录伪作的影响,本文主要围绕考古出土的龙首方身铜器进行考察。首先从类型分析入手,然后再重新认识其用途,以期从不同角度对于其研究给予推动。 展开更多
关键词 汉代 首方身铜器 生活工具 铜锉
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去学校吧,我亲爱的孩子
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《疯狂英语(初中天地)》 2019年第3期50-51,共2页
唐代颜真卿曾这样说过:“三更灯火五更鸡,正是男儿读书时。黑发不知勤学早,白首方悔读书迟。书山有路勤为径,学海无涯苦作舟。”学习是一个“修炼”的过程,炼掉我们自身的杂质,提升自身的价值。学校,就是让我们和小伙伴们一起“修炼”... 唐代颜真卿曾这样说过:“三更灯火五更鸡,正是男儿读书时。黑发不知勤学早,白首方悔读书迟。书山有路勤为径,学海无涯苦作舟。”学习是一个“修炼”的过程,炼掉我们自身的杂质,提升自身的价值。学校,就是让我们和小伙伴们一起“修炼”的地方,我们共勉、互助,一起在相同的知识中收获属于自己的不同领悟。 展开更多
关键词 首方 路勤 黑发 学校 读书 书山 价值 勤学
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The First Integral Method to Study a Class of Reaction-Diffusion Equations 被引量:1
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作者 KEYun-Quant YUJun 《Communications in Theoretical Physics》 SCIE CAS CSCD 2005年第4期597-600,共4页
In this letter, a class of reaction-diffusion equations, which arise in chemical reaction or ecology and other fields of physics, are investigated. A more general analytical solution of the equation is obtained by usi... In this letter, a class of reaction-diffusion equations, which arise in chemical reaction or ecology and other fields of physics, are investigated. A more general analytical solution of the equation is obtained by using the first integral method. 展开更多
关键词 exact solution reaction-diffusion equation first integral
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Development of land valuation approach based on hedonic model--A case study of Vientiane capital city Laos 被引量:1
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作者 Chanhda Hemmavanh YE Yan-mei +1 位作者 WU Ci-fang Ayumi Yoshida 《Chinese Business Review》 2010年第4期27-36,62,共11页
The aim of this study is to identify the variables affecting land value. Examined land was selected from the village in Vientiane capital city Laos. Data was collected from 100 villages in center of Vientiane capital ... The aim of this study is to identify the variables affecting land value. Examined land was selected from the village in Vientiane capital city Laos. Data was collected from 100 villages in center of Vientiane capital city by using survey methods. A hedonic price analysis was conducted to determine the marginal return to different land characteristics using an econometric model corrected for correlation. Parcel characteristics such as distance to public park, village income, distance of population, number of the school within 500 meters buffer, distance to the temple, distance to the major market and distance to the business center (CBD). Arc GIS 9.2 was applied to calculate the distance of the factors, after that SPSS 15.0 was used to calculate the land price characteristic based on hedonic price model. The results showed that the distance to the center of population was the main factor influencing to the land price, and followed by school and village income. Map of the land price before and after hedonic price analysis were produced. The land price valuation approaches based on hedonic price model for Vientiane capital city were developed and land price map were predicted. Hedonic price model and GIS were very useful for this research, and finally the policy of the land valuation based on GIS was developed. 展开更多
关键词 land price hedonic price model Vientiane Laos
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The Global Chief Executive Officer (CEO): Leadership Styles, Arts, and Skills
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作者 Yezdi H. Godiwalla 《Journal of Modern Accounting and Auditing》 2013年第10期1408-1415,共8页
The global chief executive officer (CEO) should quickly adjust his/her leadership styles, arts, and skills to customize for the particular host country as he/she manages the global organization in its many diverse e... The global chief executive officer (CEO) should quickly adjust his/her leadership styles, arts, and skills to customize for the particular host country as he/she manages the global organization in its many diverse environments. He/she has to quickly customize to the local needs his/her styles of strategic and operational decision-making, communication, and interpersonal approaches. His/her repertoire of leadership styles, arts, and skills has to be wider and richer in variety. He/she must quickly move from one host-country-focused approach to another, drawing the needed blend of leadership styles, arts, and skills from his/her repertoire and effectively applying them to the host country situation. Thus, a CEO must analyze his/her situation and re-orient his/her approach to fit the varying international situations, such as culture, operating, and subsidiary's organizational, economic, political, governmental, and technological. An effective CEO is perspicuous and quick of action in adjusting and modifying his/her roles, styles, arts, and leadership processes to fit the situation in which he/she is in at the moment. 展开更多
关键词 chief executive officer (CEO) leadership roles CEO responsibilities CEO skills and style arts of CEO
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Storm in the Air: The Battle Over the 1992 Cable Act
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作者 Samuel B. Hoff 《History Research》 2016年第3期121-133,共13页
Utilizing primary documents available at the George Bush Presidential Library, this study evaluates the veto record of President Bush using a case study as well as quantitative methods. The case study reviews the back... Utilizing primary documents available at the George Bush Presidential Library, this study evaluates the veto record of President Bush using a case study as well as quantitative methods. The case study reviews the background and fate of the only veto overridden during his term in office. It finds that the Bush White House had tried on several previous occasions to scrap the legislation, only to have it be reintroduced in each succeeding Congress. By 1992, when George Bush was running for reelection and in trouble politically, his team was unable to stave off defeat. The article likewise assesses the success of the Bush administration in its employment of the veto and compares the veto record of President Bush to previous and subsequent chief executives. 展开更多
关键词 VETO override PRESIDENT CONGRESS cable regulation 1992 Cable Act
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Estimation of Site Effects on Stations in the Capital Circle Region Using the Generalized Inversion Method
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作者 Shi Haixia Xiu Jigang +2 位作者 Chen Zhangli Wang Qincai Hua Wei 《Earthquake Research in China》 2010年第2期198-210,共13页
Generalized Inversion Method has been used to estimate the spatial variation of site effects,using the digital data of SH-waves recorded by 63 stations in the Capital Circle Region of China from 2001 to 2006.We gained... Generalized Inversion Method has been used to estimate the spatial variation of site effects,using the digital data of SH-waves recorded by 63 stations in the Capital Circle Region of China from 2001 to 2006.We gained the site effects of all stations participating in the calculation.We found that the site effect of rock was stabile and about 1.0 from 1.0Hz to 10.0Hz,while the site effect of deposit was high in low frequencies,about 3 ~ 7 from 1.0Hz to 8.0Hz,and the site effect was protuberant at about 5.0Hz,then fell as the frequency increased.The result shows the shape and intensity of station site effects are mainly influenced by the lithology below the station,and possibly also by the local geological structure. 展开更多
关键词 Capital Circle Region Site effects Generalized inversion method SH-wave Weighting factor
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鹤壁出土战国锐角布币 被引量:3
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作者 刘荷英 《中国钱币》 北大核心 1989年第1期38-,84,共2页
1981年11月,河南省鹤壁市石林公社狮跑泉村农民在一个土丘上发现一处战国货币窑藏。窑藏货币分装在三个圜底陶罐里,陶罐呈一字形排列。货币上尚有绳子捆绑的痕迹。经过整理,有“公”字锐角布3537枚,“垂”字锐角布1枚,圜钱11180枚,平首... 1981年11月,河南省鹤壁市石林公社狮跑泉村农民在一个土丘上发现一处战国货币窑藏。窑藏货币分装在三个圜底陶罐里,陶罐呈一字形排列。货币上尚有绳子捆绑的痕迹。经过整理,有“公”字锐角布3537枚,“垂”字锐角布1枚,圜钱11180枚,平首方足布141枚,平首圆肩方足布11枚,总计4870枚。这批货币的发现,为研究三晋货币及鹤壁地区战国时期的经济提供了珍贵的实物资料。 展开更多
关键词 布币 锐角布 首方足布 战国时期 河南省鹤壁市 字形排列 圜底 出土地点 币文 实物资料
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有关清代选官制度的重要资料——读《保举题名》碑
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作者 路远 《碑林集刊》 2003年第1期230-254,共25页
在西安碑林第五室,有一块不大引人注意的碑,既无碑题,也无额题,通常依据碑文内容,称其《保举题名》碑或《保官题名》碑。此碑圆首方座,高221厘米,宽82厘米。碑文为楷书,分10列刻462个被保举人姓名,每人名下又分两行刻其籍贯、出身,保举... 在西安碑林第五室,有一块不大引人注意的碑,既无碑题,也无额题,通常依据碑文内容,称其《保举题名》碑或《保官题名》碑。此碑圆首方座,高221厘米,宽82厘米。碑文为楷书,分10列刻462个被保举人姓名,每人名下又分两行刻其籍贯、出身,保举人姓名、官职,被保举人去向和所任官职等内容。 展开更多
关键词 姓名 选官 题名 额题 制度 官职 首方 碑文
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苏轼《集归去来辞诗》刻石与清人的苏轼接受史
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作者 傅清音 《碑林集刊》 2010年第1期173-178,共6页
清刻苏轼的《集归去来辞诗》刻石圆首方座,高265厘米,宽102厘米,内容是苏轼为追和东晋大诗人陶渊明的辞赋名篇《归去来兮辞》所作的组诗,诗题曰:'予喜渊明归去来辞因集字为诗六首。'碑末署:'元丰四年九月二十二日眉山轼书。... 清刻苏轼的《集归去来辞诗》刻石圆首方座,高265厘米,宽102厘米,内容是苏轼为追和东晋大诗人陶渊明的辞赋名篇《归去来兮辞》所作的组诗,诗题曰:'予喜渊明归去来辞因集字为诗六首。'碑末署:'元丰四年九月二十二日眉山轼书。'元丰二年(1079),苏轼因'乌台诗案'被捕入狱。 展开更多
关键词 诗人 刻石 辞赋 集字 辞因 首方 诗题
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投资古钱币门槛高、风险多
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作者 梁世燕 《中国拍卖》 2005年第4期37-37,共1页
业内人士运露,随着古代艺术品价格的逐渐高涨,古钱币的市场价格和拍卖行情也水涨船高,涉足这块市场的投资者也日益增多。
关键词 古钱币 艺术品价格 布币 首方足布 市场行情 三孔布 黄志勇 出土情况 民间性质 现代货币
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