期刊文献+
共找到4篇文章
< 1 >
每页显示 20 50 100
肥大软骨细胞在骨折愈合中的作用
1
作者 朱道宇 高俊杰 高悠水 《生物医学转化》 2023年第4期2-9,16,共9页
骨折愈合是一个多因素的过程。软骨内成骨是骨折愈合的重要途径,包括软骨骨痂的形成和软骨向骨的转化过程。肥大软骨细胞是软骨细胞的终末成熟状态,位于软骨性骨痂和骨性骨痂之间,以自分泌和旁分泌方式调节细胞基质降解、血管化、破骨... 骨折愈合是一个多因素的过程。软骨内成骨是骨折愈合的重要途径,包括软骨骨痂的形成和软骨向骨的转化过程。肥大软骨细胞是软骨细胞的终末成熟状态,位于软骨性骨痂和骨性骨痂之间,以自分泌和旁分泌方式调节细胞基质降解、血管化、破骨细胞募集和成骨细胞分化。此外,肥大软骨细胞可以转分化成为成骨祖细胞和成骨细胞,并直接促进编织骨的形成。阐明肥大软骨细胞在骨折愈合中的作用将有利于认识骨折愈合的生理机制,进而有助于促进骨折愈合治疗模式的研发,加速骨折的愈合。 展开更多
关键词 肥大软细胞 内成 骨发育学
下载PDF
成纤维生长因子在大鼠后肢骨骼发育早期不同阶段表达的变化及意义 被引量:1
2
作者 徐平 马瑞雪 《临床小儿外科杂志》 CAS 2012年第3期174-178,共5页
目的通过大鼠肢体发育早期血清学成纤维生长因子(fibroblast growth factors,FGFs)的表达以及后肢标本中碱性成纤维生长因子(base fibroblast growth factor,bFGF)的表达情况,观察其在大鼠后肢肢体骨骼发育早期过程中,组织学上... 目的通过大鼠肢体发育早期血清学成纤维生长因子(fibroblast growth factors,FGFs)的表达以及后肢标本中碱性成纤维生长因子(base fibroblast growth factor,bFGF)的表达情况,观察其在大鼠后肢肢体骨骼发育早期过程中,组织学上随时问变化的规律。方法将5只清洁级孕鼠的新生鼠分组为A、B、C、D、E五组,分别为10、6、6、8、6、6只。用ELISA法测定各组血清中FGF的浓度,并对其后肢标本进行bFGF的免疫组化染色,从而观察bFGF在关节软骨、骨骺、干骺端及骨膜中的表达情况。结果在新生小鼠的后肢标本免疫组化染色中,bFGF在软骨、骨膜和关节面均有表达,且随出生后时问的变化存在一定的规律:①在关节软骨中bFGF在关节面软骨的表达要强于中心部位的软骨,这种表达随出生后天数增加呈逐渐减弱的趋势。@bFGF在骨骺部增殖层和肥大细胞层以及骨膜内早期表达较强,随时间变化呈逐渐减弱趋势,在出生后10d以后bFGF表达已不明显。③在干骺端成骨细胞内bF-GF的表达不同于它在其他组织内的表达,一直呈现为较高表达,并不随生后时间的延长而呈现减弱趋势。结论在大鼠后肢发育早期,bFGF在后肢肢体各组织中存在良好的表达,提示它在肢体发育过程中与软骨增殖、关节发育与关节内软骨基质的形成和发育有密切的关系。 展开更多
关键词 发育/免疫 大鼠
下载PDF
Teffichthys wui sp. nov., a new perleidid fish from the Early Triassic of Jiangsu and Anhui, China
3
作者 XU Guang-Hui YUAN Zhi-Wei +3 位作者 REN Yi LIAO Jun-Ling ZHAO Li-Jun SONG Hai-Jun 《古脊椎动物学报(中英文)》 CSCD 北大核心 2024年第3期165-185,共21页
Perleididae is a group of stem neopterygian fishes known only from the Triassic.Here,we report the discovery of a new perleidid,Teffichthys wui sp.nov.,based on six well-preserved specimens from the late Smithian(Olen... Perleididae is a group of stem neopterygian fishes known only from the Triassic.Here,we report the discovery of a new perleidid,Teffichthys wui sp.nov.,based on six well-preserved specimens from the late Smithian(Olenekian,Early Triassic)marine deposits of Jurong,Jiangsu and Chaohu,Anhui,China.This new discovery documents the third and youngest species of Teffichthys,which is slightly younger than the Dienerian(Induan)T.elegans from Guizhou and the early Smithian T.madagascariensis from Madagascar.The new species shows diagnostic features of Teffichthys(presence of a spiracular,38-41 lateral line scales,and no more than three epaxial rays in the caudal fin)but differs from T.madagascariensis and T.elegans in some autapomorphies(e.g.,a horizontal opercle/subopercle contact and smooth scales with a nearly straight posterior margin).The diagnostic features for the genus Teffichthys and the family Perleididae are emended based on detailed comparisons of the new taxon with other perleidids.The phylogenetic relationships of perleidids with other stem neopterygians are discussed using a cladistic approach,and the results provide new insights into the phylogeny and classification of main stem neopterygian clades. 展开更多
关键词 Jiangsu ANHUI Early Triassic Perleidiformes OSTEOLOGY PHYLOGENY
下载PDF
CRANIODENTAL VARIATION OF MACAQUES ( Macaca ): SIZE,FUNCTION AND PHYLOGENY
4
作者 潘汝亮 Charles Oxnard 《Zoological Research》 CAS CSCD 2000年第4期308-322,共15页
In order to analyze skull variation in the genus Macaca ,seventy seven craniodental variables were taken from eleven species.They were first defined seven functional units comprising three anatomical regions.Twenty s... In order to analyze skull variation in the genus Macaca ,seventy seven craniodental variables were taken from eleven species.They were first defined seven functional units comprising three anatomical regions.Twenty seven variables were finally selected to carry out the morphology of the whole skull.The data,organized in these ways,were examined to discover variations between and within the various species.The methods used were Principal Components Analysis (PCA) and Discriminant Function Analysis (DFA).PCAs of the functional units anatomical regions,and the whole skull provided similar,though not identical,separations of species clusters in both sexes separately.These differences in structure could be related to size,sexual dimorphism,diet,ecology,classification and phylogeny.The question of size should have been easy to settle.Unfortunately,this is not the case.In this study where the raw data are measurements of the specimens,the main differences should be size.However,the size differences seem to occur in both the first and second (independent) multivariate axes.In some analyses the size differences between the species are biggest and appear in the first axis.In other analyses it is the separation between the sexes (and these too are largely size) that are the biggest and appear in the first axis.Yet in other analyses,both of these size separations,though still orthogonal to one another,present in the combination of the first two axes.This certainly implies that a single axis of body size is not present and that shape differences have not been isolated form size differences.It also implies that sexual dimorphism is a complex matter.As a result,the question of the relationships between the species is therefore also complex.One cluster of species that includes M fascicularis,M sinica and M radiata was significantly isolated from all others regardless of level of analysis.This relationship is quite different from that proposed on the anatomy of the reproductive organs (Delson,1980;Fooden,1976,1980). 展开更多
关键词 PRIMATES MACACA Craniodental variation Morphometric analysis Functional adaptation PHYLOGENY
下载PDF
上一页 1 下一页 到第
使用帮助 返回顶部