期刊文献+
共找到1篇文章
< 1 >
每页显示 20 50 100
Experimental Study on Gufusheng in Treatment of Steroid-Induced Ischemic Necrosis of Femoral Head in Rabbits 被引量:17
1
作者 袁普卫 贺西京 +3 位作者 周海哲 王国毓 王栋 李浩鹏 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2005年第4期300-303,共4页
Objective: To explore the mechanisim of compound Gufusheng in treatment of steroid-induced ischemic necrosis of femoral head (SINFH). Thirty-two rabbits were randomly divided into a blank control group (n=12) and a mo... Objective: To explore the mechanisim of compound Gufusheng in treatment of steroid-induced ischemic necrosis of femoral head (SINFH). Thirty-two rabbits were randomly divided into a blank control group (n=12) and a model group (n=20). The rabbits of the model group were established by intramuscular injection of prednisone acetate (0.32mg/kg/d) for 8 weeks, and 2 rabbits in each group were killed at the 6th and the 8th week respectively to investigate whether the model was successfully prepared. Then remainder in the model group was again randomly divided into group A (Gufusheng group, n=8) and group B (model group, n=8), while the rest of rabbits in the blank group constituted group C (n=8). The rabbits in group B and C were fed with normal saline. After treatment for 4 weeks, the serum insulin-like growth factor-1 (IGF-1) and tumor necrosis factor-α (TNF-α) levels in the rabbits of the 3 groups were determined by radioimmunoassay (RIA). The serum TNF-α decreased significantly and the IGF-1 level increased significantly in the Gufusheng group as compared with the model group (both P<0.01). Compound Gufusheng can prevent SINFH and promote repair of the tissue of necrosis of femoral head possibly via decreasing the TNF-α and increasing IGF-1 level. 展开更多
关键词 中医治疗 针灸治疗 骨复生煎液 头坏死
下载PDF
上一页 1 下一页 到第
使用帮助 返回顶部