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骨代谢标志物在骨质疏松中的应用进展 被引量:8
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作者 王健 廖燚 袁锋 《河北医药》 CAS 2021年第20期3164-3170,共7页
随着人口老龄化程度的加深,与其密切相关的骨质疏松患病率较前明显增高,易引起骨质疏松相关骨折。由于骨量的减少通常无症状,而监测骨骼生理变化的放射学测量反应缓慢,因而对其的早期诊断和监测非常困难。骨转换标记物是成骨细胞或破骨... 随着人口老龄化程度的加深,与其密切相关的骨质疏松患病率较前明显增高,易引起骨质疏松相关骨折。由于骨量的减少通常无症状,而监测骨骼生理变化的放射学测量反应缓慢,因而对其的早期诊断和监测非常困难。骨转换标记物是成骨细胞或破骨细胞在进行骨重塑过程中释放的蛋白质或蛋白质衍生物的标志物,可提供骨健康相关的骨代谢状态并对骨折风险进行评估。通过查询相关骨代谢标志物在骨质疏松应用的经典和最新文献并进行综述总结,得出结论,骨代谢标志物结合骨密度综合使用的骨平衡指数可对骨代谢变化做出快速判断,准确预测骨丢失,具体应用时需排除干扰因素,是诊断和监测骨骨质疏松状态并预测骨健康的有用辅助工具。 展开更多
关键词 代谢标志物 质疏松症 骨平衡指数 药物治疗
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Observation on clinical efficacy of tension-balance acupuncture therapy in treating knee osteoarthritis 被引量:1
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作者 黄洁 章薇 +5 位作者 娄必丹 刘智 叶勇 黄艾 李霞 李里 《World Journal of Acupuncture-Moxibustion》 2014年第2期42-46,共5页
Objective By comparison of the clinical efficacy of treating knee osteoarthritis with tension-balance acupuncture therapy and conventional acupuncture therapy, the effectiveness of treatment of knee osteoarthritis wit... Objective By comparison of the clinical efficacy of treating knee osteoarthritis with tension-balance acupuncture therapy and conventional acupuncture therapy, the effectiveness of treatment of knee osteoarthritis with tension- balance acupuncture therapy was evaluated. Methods Sixty-three patients with knee osteoarthritis in conformity with the diagnostic criteria were randomly divided into the tension-balance-acupuncture group (32 cases, balance group for short) and the conventional acupuncture group (31 cases, conventional group for short) according to random number table. In the balance group, patients with the pain in the anterior flexor group were needled at Biguan (髀关 ST 31), Fengshi (风市 GB 31), Heding (鹤顶 EX-LE 2),Dubi (犊鼻 ST 35), Yanglingquan (阳陵泉 GB 34), Xuehai (血海 SP 10) and Liangqiu (梁丘 ST 34) .Afterwards the patients were repositioned in prone position. They were given the treatment by needling at Huantiao (环跳 GB 30), Chengfu (承扶 BL 36), Weizhong (委中 BL 40), Weiyang (委阳 BL 39), Yinlingquan (阴陵泉 SP 9), Ququan (曲泉 LV 8) and Chengshan(承山 BL 57).Patients with the pain in the posterior extensor group were needled at ST 31, GB 31, EX-LE2, ST 35, GB 34, SP 10 and ST 34 .Then the patients were repositioned in prone position. They were given the treatment by needling at GB 30, BL 36, BL 40, BL 39, SP 9, LV 8 and BL 57. They were treated once a day with five days as a course of treatment and two days as an interval. After three courses, Lequesne indiceses before and after the treatment and clinical efficacy of the treatment were observed. In the conventional group, patients were treated in a sitting position by needling at ST 35, Xiyang (膝眼 EX-LE 5),Zusanli(足三里 ST 36), GB 34, Xuanzhong (悬钟 GB 39), SP 9, EX-LE2, ST 34, Shenshu (肾俞 BL 23) and Pishu (脾俞 20). They were treated once a day with five days as a course of treatment and two days as an interval. After three courses, the clinical efficacy of the treatment was observed. Results After three courses, improved Lequesne indices score was (5.55± 1.08) in the balance group while improved Lequesne indices score was (2.14 ± 0.57) in the conventional group, indicating that improved Lequesne indices score in the balance group was superior to that of the conventional group with the significant difference (P〈0.05); efficacy rate in the balance group was 84.37% while that of the conventional group was 58.06%, and efficacy rate in the balance group was superior to that of the conventional group (P〈0.01). Conclusion Clinical efficacy of treatment of knee osteoarthritis in the balance group was superior to that of the conventional group, worthy of clinical promotion. 展开更多
关键词 tension balance ACUPUNCTURE knee osteoarthritis Lequesneindices randomized controlled trial
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