博宁结合中药治疗63例肿瘤性骨溶解性骨破坏的临床研究

目的观察博宁配合中药补肾活血方对肿瘤性骨溶解性骨破坏骨痛及骨质修复的疗效。方法临床确诊为肿瘤性骨溶解性骨破坏伴骨痛患者63例,随机分为博宁+补肾活血方组(治疗组)及单纯博宁组(对照组)。博宁首次予90mg,然后60mg/2周×2次;补肾活血方每日一剂×8周。结果治疗组骨痛缓解率76.67%,优于对照组的60.61%,P<0.05。8周后骨质修复,治疗组为26.67%,对照组为6.06%,P<0.05。结论补肾活血方对博宁有增效作用,中药补肾活血方配合博宁对肿瘤性骨溶解性骨破坏骨痛有较好的缓解作用,并能促进骨骼修复。

中药结合博宁治疗肿瘤性骨溶解性骨破坏疗效研究

观察博宁配合中药补肾活血方对肿瘤性骨溶解性骨破坏骨痛及骨质修复的疗效。临床确诊为肿瘤性骨溶解性骨破坏伴骨痛患者63例,随机分为博宁加补肾活血方组(治疗组)及单纯博宁组(对照组)。结果:治疗组骨痛缓解率76.67%,优于对照组的60.61%,P<0.05。8周后骨质修复,治疗组为26.67%,对照组为6.06%,P<0.05。提示:补肾活血方对博宁有增效作用,博宁配合中药补肾活血方对肿瘤性骨溶解性骨破坏骨痛有较好的缓解作用,并能促进骨骼修复。

暴发性痤疮伴局部牙槽骨溶解性破坏十年追踪观察

暴发性痤疮（acne fulminans,AF）是临床上较罕见的皮肤病,至今国内外仅报道100例左右[1].该病多见于青少年男性,其临床特点是发病突然,往往伴有发热和关节疼痛等全身症状,对抗生素治疗效果不佳,皮质类固醇治疗有显著疗效.皮损以胸背部为主,亦可出现于面颈部.局部疼痛明显,可形成糜烂、溃疡.疼痛部位的骨X线片可见骨溶解性破坏或骨扫描摄入量增加[1].骨破坏常见于胸骨病变,而伴牙槽骨破坏的AF尚少见.北京大学口腔医学院·口腔医院牙周科收治1例发生于面颊部的AF伴局部牙槽骨急性溶解性破坏病例,已随访10年,报道如下.

Clinical Observation on Curative Effect of Dissolving Phlegm-Stasis on 50 Cases of Knee Osteoarthritis

Objective： To observe the curative effect of dissolving phlegm-stasis on knee osteoarthritis. Methods： The 100 patients with knee osteoarthritis were randomly divided into two groups. The 50 patients in the treatment group orally took Chinese medicine while the other 50 patients in the control groups orally took Votalin and Vitamin C for one week as a course of treatment. At the end of 2-week treatment, analytic comparison was carried in evaluate the curative effect and the changes in total score of symptoms before and after treatment between the two groups. Results： The total score of symptoms after treatment was significantly lower than that before treatment in both groups （P〈0.01, P〈0.05）. The total score after treatment of patients with X-ray grade I and II in the treatment group was more obviously reduced as compared to the control group （P〈0.05）. The remarkably effective rate after treatment of patients with X-ray grade I and It in the treatment group was also higher than that in the control group （P〈0.05）. Conclusion： The treatment of knee osteoarthritis with dissolving phlegm-stasis can effectively improve the clinical symptoms.