目的:观察中医骨科综合疗法治疗老年性膝骨关节炎的临床疗效。方法:60例老年性膝骨关节炎患者按照随机数字表法将患者随机平均分为对照组和试验组。对照组给予双氯芬酸钠肠溶缓释胶囊治疗,试验组给予中医骨科综合疗法治疗。两组均治疗7...目的:观察中医骨科综合疗法治疗老年性膝骨关节炎的临床疗效。方法:60例老年性膝骨关节炎患者按照随机数字表法将患者随机平均分为对照组和试验组。对照组给予双氯芬酸钠肠溶缓释胶囊治疗,试验组给予中医骨科综合疗法治疗。两组均治疗7 d,比较两组患者临床疗效及西安大略和麦克马斯特大学骨关节炎指数(western ontario and McMaster university osteoarthritis index, WOMAC)评分。结果:试验组有效率为93.3%,对照组有效率为73.3%,两组比较,差异有统计学意义(P<0.05)。试验组WOMAC评分中膝关节肿胀、疼痛、酸软以及活动受限评分均低于对照组,差异均有统计学意义(P<0.05)。结论:中医骨科综合疗法治疗老年性膝骨关节炎临床疗效显著,能够显著改善患者临床症状,降低WOMAC评分。展开更多
Objective ： To study the effect of allograft compound vertebra on vertebral reconstruction in rabbits so as to provide biomechanical direction for manufacturing and selecting vertebral reconstruction materials. Meth...Objective ： To study the effect of allograft compound vertebra on vertebral reconstruction in rabbits so as to provide biomechanical direction for manufacturing and selecting vertebral reconstruction materials. Methods： Twenty-five healthy New Zealand white rabbits were divided randomly into three groups： normal group （ Group A, n = 5 ） ,iliac bone graft group （ Group B, n = 10） and allograft compound vertebra group （ Group C, n = 10）. After C4 was resected, iliac bone implantation and allograft bone cage transplantation were fulfilled in Group B and Group C, respectively. Every 5 rabbits from Group B and Group C were selected to test the biomechanical strength and biological activity one and two months postoperatively. Results： No significant statistical difference was found between Group A and Group C one and two monthspostoperatively （ P 〉 0.05 ）. The biomechanical strength of Group B was much weaker than that of Group A and Group C one month postoperatively （P 〈 0.05 ）, but at two months postoperatively, no statistical difference was found among the three groups. The biological activity and vertebral moulding ability of Group C were better than those of Group B at one and two months postoperatively. Conclusions： Compound vertebra, which is made up of allograft cortical bone cage and autogenous cancellous bone, shows instantaneous and permanent biomechanical stability and biological activity, therefore, it is an ideal material for vertebral reconstruction.展开更多
文摘目的:观察中医骨科综合疗法治疗老年性膝骨关节炎的临床疗效。方法:60例老年性膝骨关节炎患者按照随机数字表法将患者随机平均分为对照组和试验组。对照组给予双氯芬酸钠肠溶缓释胶囊治疗,试验组给予中医骨科综合疗法治疗。两组均治疗7 d,比较两组患者临床疗效及西安大略和麦克马斯特大学骨关节炎指数(western ontario and McMaster university osteoarthritis index, WOMAC)评分。结果:试验组有效率为93.3%,对照组有效率为73.3%,两组比较,差异有统计学意义(P<0.05)。试验组WOMAC评分中膝关节肿胀、疼痛、酸软以及活动受限评分均低于对照组,差异均有统计学意义(P<0.05)。结论:中医骨科综合疗法治疗老年性膝骨关节炎临床疗效显著,能够显著改善患者临床症状,降低WOMAC评分。
基金the Natural Science Fund in Hubei Province(No.2004ABA171).
文摘Objective ： To study the effect of allograft compound vertebra on vertebral reconstruction in rabbits so as to provide biomechanical direction for manufacturing and selecting vertebral reconstruction materials. Methods： Twenty-five healthy New Zealand white rabbits were divided randomly into three groups： normal group （ Group A, n = 5 ） ,iliac bone graft group （ Group B, n = 10） and allograft compound vertebra group （ Group C, n = 10）. After C4 was resected, iliac bone implantation and allograft bone cage transplantation were fulfilled in Group B and Group C, respectively. Every 5 rabbits from Group B and Group C were selected to test the biomechanical strength and biological activity one and two months postoperatively. Results： No significant statistical difference was found between Group A and Group C one and two monthspostoperatively （ P 〉 0.05 ）. The biomechanical strength of Group B was much weaker than that of Group A and Group C one month postoperatively （P 〈 0.05 ）, but at two months postoperatively, no statistical difference was found among the three groups. The biological activity and vertebral moulding ability of Group C were better than those of Group B at one and two months postoperatively. Conclusions： Compound vertebra, which is made up of allograft cortical bone cage and autogenous cancellous bone, shows instantaneous and permanent biomechanical stability and biological activity, therefore, it is an ideal material for vertebral reconstruction.
