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运动性骨骼肌损伤后不同时刻大鼠肱三头肌超微结构及肌酸激酶的变化 被引量:4
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作者 孙良 赵刚 《沈阳体育学院学报》 CSSCI 北大核心 2015年第3期74-78,共5页
通过建立大鼠下坡跑运动损伤模型,研究运动损伤后骨骼肌超微损伤和恢复发生的机制。主要结果:运动后大鼠肱三头肌超微结构发生改变,电镜下可见肌纤维排列紊乱,Z线异常(包括Z线流、Z线模糊、Z线扭曲和Z线消失),肌细胞膜模糊、溶解,线... 通过建立大鼠下坡跑运动损伤模型,研究运动损伤后骨骼肌超微损伤和恢复发生的机制。主要结果:运动后大鼠肱三头肌超微结构发生改变,电镜下可见肌纤维排列紊乱,Z线异常(包括Z线流、Z线模糊、Z线扭曲和Z线消失),肌细胞膜模糊、溶解,线粒体肿胀、空泡样改变等。这些现象随运动时间的不同而发生改变。运动后24 h表现最为明显,而后逐渐恢复;运动后72 h恢复明显,但没有完全恢复。运动后即刻血清CK活性(2035.42±426.49)U/L与对照组血清CK活性(293.66±76.07)U/L相比,非常显著增高(P〈0.01),达到了峰值,而后逐渐恢复。运动后72h组血清CK活性(425.51±143.34)U/L与即刻组血清CK活性相比已显著恢复(P〈0.01)。结论:运动后24h骨骼肌的损伤程度最为严重,72 h后可明显恢复;大强度运动对CK的活性具有非常显著的影响,血清CK活性的变化能够反映运动后骨骼肌超微结构损伤的状况。 展开更多
关键词 运动骨骼肌损伤 骨骼肌超微结 肌酸激酶
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Effects of exercise-induced skeletal muscle damage and ultrastructure of muscle
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作者 Xiuchang Yang 《International Journal of Technology Management》 2014年第5期109-111,共3页
Micro- injury (exercise-induced muscle damage, EIMD) will cause a temporary decline in muscle function, if not handled properly, it could cause more serious injury or overtraining, and even lead to the end of the at... Micro- injury (exercise-induced muscle damage, EIMD) will cause a temporary decline in muscle function, if not handled properly, it could cause more serious injury or overtraining, and even lead to the end of the athletes ' sports life. However, some studies have shown that an appropriate period of eccentric exercise training resulted in EIMD while promoted heart muscle fiber hypertrophy and corresponding muscle growth faster than exercise training, and there are the typical " repetitive training effect" , ie after a period of the EIMD recovery, the muscle' s injury or delayed onset muscle soreness (DOMS) caused by the same movement is significantly reduced. So its deep study could help to guide the athlete to avoid or mitigate the negative effects which brought by EIMD, while could help to further clarify the process of the body to adapt to exercise training or mechanism. 展开更多
关键词 EXERCISE skeletal muscle damage ultrastructure of muscle
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