Objective： To reveal the action mechanism and efficacy of electroacupuncture（EA） plus external application of Wei Ling Xian（Radix Clematidis） extract in treating knee osteoarthritis（KOA）, for providing theoreti...Objective： To reveal the action mechanism and efficacy of electroacupuncture（EA） plus external application of Wei Ling Xian（Radix Clematidis） extract in treating knee osteoarthritis（KOA）, for providing theoretical evidence and novel plan for the treatment of KOA. Methods： Totally 284 inpatients were divided into an EA group and an observation group by the random number table, 142 cases in each group. The EA group was intervened by EA, ultrashort waves, and oral administration of Glucosamine Hydrochloride capsules; while the observation group was by external application of Wei Ling Xian（Radix Clematidis） extract at topical area in addition to the treatment given to the EA group. The intervention lasted 14 d in both groups. X-ray examination of knee joint was ordered before and after treatment, as well as the detection of positive expression of matrix metalloproteinase-1（MMP-1） in cartilage of knee joint, hyaluronic acid（HA） and interleukin-1β（IL-1β） in the inflammatory effusion; the Western Ontario and McM aster Universities osteoarthritis index（WOMAC） and visual analogue scale（VAS） were adopted to evaluate the clinical efficacy. Results： In the observation group, the X-ray examination result of knee joint was significantly improved, the positive expressions of MMP-1 and IL-1β content were significantly decreased, the level of HA was increased, WOMAC and VAS scores dropped, and the total effective rate was 91.5%, which were significantly different from those in the EA group（P〈0.05）. Conclusion： EA plus external application of Wei Ling Xian（Radix Clematidis） extract can produce a more significant efficacy in treating KOA compared to ordinary EA treatment.展开更多
Objective： To observe the short-term efficacy of massaging quadriceps on knee osteoarthritis （KOA）. Methods： Totally 30 KOA patients were enrolled and treated mainly with massaging quadriceps, 20 min for each sess...Objective： To observe the short-term efficacy of massaging quadriceps on knee osteoarthritis （KOA）. Methods： Totally 30 KOA patients were enrolled and treated mainly with massaging quadriceps, 20 min for each session, once a day, 2 weeks as a treatment course, and for 2 courses in total. After treatment, the changes of visual analogue scale （VAS） and Western Ontario and McMaster Universities osteoarthritis index （WOMAC） were observed. Result： The VAS and WOMAC scores dropped after treatment, with a statistically significant difference （P〈0.01）. After a course of treatment, the recovery rate was 33.3% and the total effective rate was 86.7%; after 2 courses, the recovery rate was 60.0% and the total effect rate was 96.7%. Conclusion： Massaging quadriceps can alleviate pain, improve the function of knee joint, and produce a significant short-term efficacy in treating KOA.展开更多
Objective： To observe the clinical effects of herbal cake-partitioned moxibustion in the treatment of knee osteoarthritis （KOA）. Methods： A total of 120 cases with KOA were randomly divided into two groups by the ...Objective： To observe the clinical effects of herbal cake-partitioned moxibustion in the treatment of knee osteoarthritis （KOA）. Methods： A total of 120 cases with KOA were randomly divided into two groups by the random digital table, 60 cases in each group. The herbal cake-partitioned moxibustion （HCPM） group was treated by herbal cake-partitioned moxibustion, once per day and five days per week, with ten sessions as one course. The Western medication （WM） group was treated by the oral administration of Diclofenac Sodium Sustained-release Tablets. The knee functions of the patients were assessed by Western Ontario and McMaster Universities osteoarthritis index （WOMAC） before and after the treatment. The clinical effects were observed in the two groups after four-week continuous treatment. Results： The total effective rate was 86.7% in the HCPM group and 73.3% in the WM group. The difference in the total effective rate between the two groups was statistically significant （P〈0.05）. After treatment, WOMAC scores in the two groups were statistically different than those of the same group before the treatment （both P〈0.05）; the difference between the two groups were statistically significant （P〈0.05）. Conclusion： Herbal cake-partitioned moxibustion and oral administration of Didofenac Sodium Sustained-re;ease Tablets can improve the knee functions of KOA patients, but the therapeutic effect was better by herbal cake-partitioned moxibustion than by oral administration of Diclofenac Sodium Sustained-release Tablets.展开更多
Strain of infrapatellar fat pad extensively occurs in people aged over 30 years, who often walk up hills or squat while working. The clinical manifestations are aching and weakness in the knee joints, aggravated when ...Strain of infrapatellar fat pad extensively occurs in people aged over 30 years, who often walk up hills or squat while working. The clinical manifestations are aching and weakness in the knee joints, aggravated when the knee joints are totally extended. Discomfort occurs in mild cases only when walking for long or going up and down the stairs. There is aching feeling in moderate cases when the patients are quiet. The pain is aggravated during exercises when the knee joints are half flexed and the patient can not stand up when squatting for prolonged periods of time. There are aching and weak feelings in the severe cases.展开更多
Objective： To observe the clinical efficacy of puncturing lumbar acupoints in treating knee joint pain. Methods： Thirty-seven patients suffered from knee joint pain were treated by puncturing lumbar acupoints combin...Objective： To observe the clinical efficacy of puncturing lumbar acupoints in treating knee joint pain. Methods： Thirty-seven patients suffered from knee joint pain were treated by puncturing lumbar acupoints combined with cupping therapy. Visual Analog Scale （VAS） was scored before and after the first treatment as well as the second treatment. Result： Before treatment, VAS score was 5.3±1.2. After the first treatment, VAS score descended to 1.9±0.8. Before the second treatment, VAS score was 2.1±0.7. After the second treatment, VAS score descended to 0.7±0.6. Conclusion： Puncturing lumbar acupoints is quite effective in treating knee joint pain caused by lumbar diseases.展开更多
基金supported by Project of Science and Technology Department of Hubei Province~~
文摘Objective： To reveal the action mechanism and efficacy of electroacupuncture（EA） plus external application of Wei Ling Xian（Radix Clematidis） extract in treating knee osteoarthritis（KOA）, for providing theoretical evidence and novel plan for the treatment of KOA. Methods： Totally 284 inpatients were divided into an EA group and an observation group by the random number table, 142 cases in each group. The EA group was intervened by EA, ultrashort waves, and oral administration of Glucosamine Hydrochloride capsules; while the observation group was by external application of Wei Ling Xian（Radix Clematidis） extract at topical area in addition to the treatment given to the EA group. The intervention lasted 14 d in both groups. X-ray examination of knee joint was ordered before and after treatment, as well as the detection of positive expression of matrix metalloproteinase-1（MMP-1） in cartilage of knee joint, hyaluronic acid（HA） and interleukin-1β（IL-1β） in the inflammatory effusion; the Western Ontario and McM aster Universities osteoarthritis index（WOMAC） and visual analogue scale（VAS） were adopted to evaluate the clinical efficacy. Results： In the observation group, the X-ray examination result of knee joint was significantly improved, the positive expressions of MMP-1 and IL-1β content were significantly decreased, the level of HA was increased, WOMAC and VAS scores dropped, and the total effective rate was 91.5%, which were significantly different from those in the EA group（P〈0.05）. Conclusion： EA plus external application of Wei Ling Xian（Radix Clematidis） extract can produce a more significant efficacy in treating KOA compared to ordinary EA treatment.
文摘Objective： To observe the short-term efficacy of massaging quadriceps on knee osteoarthritis （KOA）. Methods： Totally 30 KOA patients were enrolled and treated mainly with massaging quadriceps, 20 min for each session, once a day, 2 weeks as a treatment course, and for 2 courses in total. After treatment, the changes of visual analogue scale （VAS） and Western Ontario and McMaster Universities osteoarthritis index （WOMAC） were observed. Result： The VAS and WOMAC scores dropped after treatment, with a statistically significant difference （P〈0.01）. After a course of treatment, the recovery rate was 33.3% and the total effective rate was 86.7%; after 2 courses, the recovery rate was 60.0% and the total effect rate was 96.7%. Conclusion： Massaging quadriceps can alleviate pain, improve the function of knee joint, and produce a significant short-term efficacy in treating KOA.
文摘Objective： To observe the clinical effects of herbal cake-partitioned moxibustion in the treatment of knee osteoarthritis （KOA）. Methods： A total of 120 cases with KOA were randomly divided into two groups by the random digital table, 60 cases in each group. The herbal cake-partitioned moxibustion （HCPM） group was treated by herbal cake-partitioned moxibustion, once per day and five days per week, with ten sessions as one course. The Western medication （WM） group was treated by the oral administration of Diclofenac Sodium Sustained-release Tablets. The knee functions of the patients were assessed by Western Ontario and McMaster Universities osteoarthritis index （WOMAC） before and after the treatment. The clinical effects were observed in the two groups after four-week continuous treatment. Results： The total effective rate was 86.7% in the HCPM group and 73.3% in the WM group. The difference in the total effective rate between the two groups was statistically significant （P〈0.05）. After treatment, WOMAC scores in the two groups were statistically different than those of the same group before the treatment （both P〈0.05）; the difference between the two groups were statistically significant （P〈0.05）. Conclusion： Herbal cake-partitioned moxibustion and oral administration of Didofenac Sodium Sustained-re;ease Tablets can improve the knee functions of KOA patients, but the therapeutic effect was better by herbal cake-partitioned moxibustion than by oral administration of Diclofenac Sodium Sustained-release Tablets.
文摘Strain of infrapatellar fat pad extensively occurs in people aged over 30 years, who often walk up hills or squat while working. The clinical manifestations are aching and weakness in the knee joints, aggravated when the knee joints are totally extended. Discomfort occurs in mild cases only when walking for long or going up and down the stairs. There is aching feeling in moderate cases when the patients are quiet. The pain is aggravated during exercises when the knee joints are half flexed and the patient can not stand up when squatting for prolonged periods of time. There are aching and weak feelings in the severe cases.
文摘Objective： To observe the clinical efficacy of puncturing lumbar acupoints in treating knee joint pain. Methods： Thirty-seven patients suffered from knee joint pain were treated by puncturing lumbar acupoints combined with cupping therapy. Visual Analog Scale （VAS） was scored before and after the first treatment as well as the second treatment. Result： Before treatment, VAS score was 5.3±1.2. After the first treatment, VAS score descended to 1.9±0.8. Before the second treatment, VAS score was 2.1±0.7. After the second treatment, VAS score descended to 0.7±0.6. Conclusion： Puncturing lumbar acupoints is quite effective in treating knee joint pain caused by lumbar diseases.
