85例高 IgA 血症中单纯 IgA 增高52例,IgA 并 IgG 增高28例,IgA 并IgM 增高5例,男、女之比为1.58∶1,74.1%(63例)患儿年龄>7岁;95.3%(81例)的患儿血清 IgA 呈轻~中度增高。其相关疾病包括肾小球疾病48例、风湿热或风湿性心脏病17...85例高 IgA 血症中单纯 IgA 增高52例,IgA 并 IgG 增高28例,IgA 并IgM 增高5例,男、女之比为1.58∶1,74.1%(63例)患儿年龄>7岁;95.3%(81例)的患儿血清 IgA 呈轻~中度增高。其相关疾病包括肾小球疾病48例、风湿热或风湿性心脏病17例、过敏性紫癜10例、其他自身免疫性疾病7例及其他疾患3例。大多数病儿血清 IgA 增高伴有血沉、循环免疫复合物、抗链球菌溶血素“O”抗体增高和血清 C_3水平异常,部分病儿伴有淋巴母细胞转化率降低。提示高 IgA 血症系机体免疫功能紊乱的表现之一。展开更多
To report a case of recurrent Staphylococcus aureus chalazia in a patient with hyperimmunoglobulinemia E syndrome (Job’s Syndrome). Case report. Three separa te surgical incisions and curettages of multiple, recurren...To report a case of recurrent Staphylococcus aureus chalazia in a patient with hyperimmunoglobulinemia E syndrome (Job’s Syndrome). Case report. Three separa te surgical incisions and curettages of multiple, recurrent chalazia of the righ t upper eyelid were performed over a course of 3 months. Cultures and pathologic specimens were obtained. Postoperative treatment consisted of oral erythromycin and amoxicillin/-clavulonate, topical tobr amycin/dexamethasone ointment, and warm compresses. Pathology of the tarsus co nfirmed the diagnosis of multiple chalazia. Cultures of the chalazia contents we re positive for Staphylococcus aureus. No further recurrence was observed follow ing the third surgical procedure over a 3-month follow-up period. Characterist ic Staphylococcus aureus skin infections in immunodeficient patients with hyperi mmunoglobulinemia E syndrome can involve the eyelids and may be recurrent despit e appropriate medical and surgical therapy.展开更多
文摘85例高 IgA 血症中单纯 IgA 增高52例,IgA 并 IgG 增高28例,IgA 并IgM 增高5例,男、女之比为1.58∶1,74.1%(63例)患儿年龄>7岁;95.3%(81例)的患儿血清 IgA 呈轻~中度增高。其相关疾病包括肾小球疾病48例、风湿热或风湿性心脏病17例、过敏性紫癜10例、其他自身免疫性疾病7例及其他疾患3例。大多数病儿血清 IgA 增高伴有血沉、循环免疫复合物、抗链球菌溶血素“O”抗体增高和血清 C_3水平异常,部分病儿伴有淋巴母细胞转化率降低。提示高 IgA 血症系机体免疫功能紊乱的表现之一。
文摘To report a case of recurrent Staphylococcus aureus chalazia in a patient with hyperimmunoglobulinemia E syndrome (Job’s Syndrome). Case report. Three separa te surgical incisions and curettages of multiple, recurrent chalazia of the righ t upper eyelid were performed over a course of 3 months. Cultures and pathologic specimens were obtained. Postoperative treatment consisted of oral erythromycin and amoxicillin/-clavulonate, topical tobr amycin/dexamethasone ointment, and warm compresses. Pathology of the tarsus co nfirmed the diagnosis of multiple chalazia. Cultures of the chalazia contents we re positive for Staphylococcus aureus. No further recurrence was observed follow ing the third surgical procedure over a 3-month follow-up period. Characterist ic Staphylococcus aureus skin infections in immunodeficient patients with hyperi mmunoglobulinemia E syndrome can involve the eyelids and may be recurrent despit e appropriate medical and surgical therapy.