颅内动脉粥样硬化是缺血性卒中(Ischemic stroke, IS)的主要原因之一,其致死率和致残率较高。颅内血管病变的发病机制通常始于血管壁,因此,早期识别斑块成分及其易损性对临床诊疗和患者预后至关重要。颅内血管传统影像学评价方法,如DSA...颅内动脉粥样硬化是缺血性卒中(Ischemic stroke, IS)的主要原因之一,其致死率和致残率较高。颅内血管病变的发病机制通常始于血管壁,因此,早期识别斑块成分及其易损性对临床诊疗和患者预后至关重要。颅内血管传统影像学评价方法,如DSA、CTA、MRA,主要评价病变血管管腔狭窄程度,不能评价管壁情况并具有电离辐射危害或有创性。高分辨率血管壁成像(High-resolution magnetic resonance vessell wall imaging, HR-VWI)作为一项新兴的无创检查技术,可以清晰地显示颅内动脉管壁情况,精准对斑块进行定量及定性分析,进而识别斑块的易损性特征。本文旨在深入探讨HR-VWI在评估颅内动脉粥样硬化斑块影像学特征与缺血性卒中之间的相关性,为患者早期发现及诊疗提供可行性方向。Intracranial atherosclerosis, a major cause of ischemic stroke (IS), carries high mortality and morbidity. Early detection of plaque composition and vulnerability is crucial due to its vessel wall origin. Traditional imaging (DSA, CTA, MRA) focuses on lumen stenosis, lacking wall assessment and with radiation or invasive risks. HR-VWI (High-resolution magnetic resonance vessell wall imaging), an emerging non-invasive technique, visualizes intracranial arterial walls, precisely analyzing plaques and identifying their vulnerability. This article aims to delve into the correlation between HR-VWI in assessing intracranial atherosclerotic plaque imaging features and ischemic stroke, providing a feasible direction for early detection, diagnosis, and treatment of patients.展开更多
文摘颅内动脉粥样硬化是缺血性卒中(Ischemic stroke, IS)的主要原因之一,其致死率和致残率较高。颅内血管病变的发病机制通常始于血管壁,因此,早期识别斑块成分及其易损性对临床诊疗和患者预后至关重要。颅内血管传统影像学评价方法,如DSA、CTA、MRA,主要评价病变血管管腔狭窄程度,不能评价管壁情况并具有电离辐射危害或有创性。高分辨率血管壁成像(High-resolution magnetic resonance vessell wall imaging, HR-VWI)作为一项新兴的无创检查技术,可以清晰地显示颅内动脉管壁情况,精准对斑块进行定量及定性分析,进而识别斑块的易损性特征。本文旨在深入探讨HR-VWI在评估颅内动脉粥样硬化斑块影像学特征与缺血性卒中之间的相关性,为患者早期发现及诊疗提供可行性方向。Intracranial atherosclerosis, a major cause of ischemic stroke (IS), carries high mortality and morbidity. Early detection of plaque composition and vulnerability is crucial due to its vessel wall origin. Traditional imaging (DSA, CTA, MRA) focuses on lumen stenosis, lacking wall assessment and with radiation or invasive risks. HR-VWI (High-resolution magnetic resonance vessell wall imaging), an emerging non-invasive technique, visualizes intracranial arterial walls, precisely analyzing plaques and identifying their vulnerability. This article aims to delve into the correlation between HR-VWI in assessing intracranial atherosclerotic plaque imaging features and ischemic stroke, providing a feasible direction for early detection, diagnosis, and treatment of patients.
