According to the structural characteristics of hazardous waste landfill and the leakage current model of high voltage DC Landfill leakage detection, a sealed model is established detail. The detection layer of the haz...According to the structural characteristics of hazardous waste landfill and the leakage current model of high voltage DC Landfill leakage detection, a sealed model is established detail. The detection layer of the hazardous waste landfill is considered as a sealed assumed that the source current flows through the leak entirely. The leak is regard and analyzed in space and it is ed as a positive current resource ＋ I located at the current entrance or a negative resource - I located at the current exit, which depends on the placement of the current supply. The electrical potential of an arbitrary in detection layer satisfies Poisson equation. The boundary condition is regarded as a natural bound- ary condition for the high resistivity of high density polyethylene （HDPE） membrane. Based on which a numerical calculation method is developed. Satisfactory agreement between experimental da- ta and simulated data validates the analysis. Parametric studies show that a larger horizontal distance between the power supply electrode and leak and a smaller distance between the detector electrodes and the detected liner are helpful to leak location. More parametric curves show that parameters leaks can be detected effectively with optimum selection of field survey.展开更多
Acute myeloid leukemia(AML) is a genetically heterogeneous myeloid malignancy that occurs more commonly in adults, and has an increasing incidence, most likely due to increasing age. Precise diagnostic classification ...Acute myeloid leukemia(AML) is a genetically heterogeneous myeloid malignancy that occurs more commonly in adults, and has an increasing incidence, most likely due to increasing age. Precise diagnostic classification of AML requires clinical and pathologic information, the latter including morphologic, immunophenotypic, cytogenetic and molecular genetic analysis. Risk stratification in AML requires cytogenetics evaluation as the most important predictor, with genetic mutations providing additional necessary information. AML with normal cytogenetics comprises about 40%-50% of all AML, and has been intensively investigated. The currently used 2008 World Health Organization classification of hematopoietic neoplasms has been proposed to be updated in2016, also to include an update on the classification of AML, due to the continuously increasing application of genomic techniques that have led to major advances in our knowledge of the pathogenesis of AML. The purpose of this review is to describe some of these recent major advances in the diagnostic classification and risk stratification of AML.展开更多
基金Supported by the National Basic Research Development Program of China(No.2010CB428506)the National High Technology Research and Development Program(No.2007AA061303)Beijing Higher Education Young Elite Teacher Project(YETP1756)
文摘According to the structural characteristics of hazardous waste landfill and the leakage current model of high voltage DC Landfill leakage detection, a sealed model is established detail. The detection layer of the hazardous waste landfill is considered as a sealed assumed that the source current flows through the leak entirely. The leak is regard and analyzed in space and it is ed as a positive current resource ＋ I located at the current entrance or a negative resource - I located at the current exit, which depends on the placement of the current supply. The electrical potential of an arbitrary in detection layer satisfies Poisson equation. The boundary condition is regarded as a natural bound- ary condition for the high resistivity of high density polyethylene （HDPE） membrane. Based on which a numerical calculation method is developed. Satisfactory agreement between experimental da- ta and simulated data validates the analysis. Parametric studies show that a larger horizontal distance between the power supply electrode and leak and a smaller distance between the detector electrodes and the detected liner are helpful to leak location. More parametric curves show that parameters leaks can be detected effectively with optimum selection of field survey.
文摘Acute myeloid leukemia(AML) is a genetically heterogeneous myeloid malignancy that occurs more commonly in adults, and has an increasing incidence, most likely due to increasing age. Precise diagnostic classification of AML requires clinical and pathologic information, the latter including morphologic, immunophenotypic, cytogenetic and molecular genetic analysis. Risk stratification in AML requires cytogenetics evaluation as the most important predictor, with genetic mutations providing additional necessary information. AML with normal cytogenetics comprises about 40%-50% of all AML, and has been intensively investigated. The currently used 2008 World Health Organization classification of hematopoietic neoplasms has been proposed to be updated in2016, also to include an update on the classification of AML, due to the continuously increasing application of genomic techniques that have led to major advances in our knowledge of the pathogenesis of AML. The purpose of this review is to describe some of these recent major advances in the diagnostic classification and risk stratification of AML.
