目的高-中危险度与低-极低危险度组胃间质瘤的影像诊断。方法回顾性分析2015年4月—2017年12月期间该院50例经手术病理证实的胃间质瘤患者的CT影像及病理资料,根据危险度不同,分为高-中危险组(24例)与低-极低危险组(26例),观察两组患者...目的高-中危险度与低-极低危险度组胃间质瘤的影像诊断。方法回顾性分析2015年4月—2017年12月期间该院50例经手术病理证实的胃间质瘤患者的CT影像及病理资料,根据危险度不同,分为高-中危险组(24例)与低-极低危险组(26例),观察两组患者是否在CT特征上有差异。结果高-中级别组胃间质瘤钙化10例、坏死23例、形态(分叶)18例、最大径>4 cm 20例;低-极低级别组钙化3例、坏死10例、形态(分叶)7例、最大径>4 cm 8例,(P=0.035、0.000、0.001、0.001),高-中级别组溃疡13例、混合生长9例、年龄(56.95±14.22)岁、平扫CT值(31.95±8.57)、动脉期CT值(61.79±20.76)、门静脉期CT值(70.50±19.34);低-极低级别组溃疡11例、混合生长6例、年龄(55.50±11.11)、平扫CT值(34.69±7.44)、动脉期CT值(62.15±21.13)、门静脉期CT值(73.03±26.16),(P=0.402、0.266、0.687、0.237、0.952、0.700,χ~2=0.703,1.236,0.406,-1.199,-0.061,-0.387)。结论高-中危险度与低-极低危险度组胃间质瘤CT影像征象,对胃间质瘤危险度的分级具有重要的参考价值。展开更多
Acute myeloid leukemia(AML) is a genetically heterogeneous myeloid malignancy that occurs more commonly in adults, and has an increasing incidence, most likely due to increasing age. Precise diagnostic classification ...Acute myeloid leukemia(AML) is a genetically heterogeneous myeloid malignancy that occurs more commonly in adults, and has an increasing incidence, most likely due to increasing age. Precise diagnostic classification of AML requires clinical and pathologic information, the latter including morphologic, immunophenotypic, cytogenetic and molecular genetic analysis. Risk stratification in AML requires cytogenetics evaluation as the most important predictor, with genetic mutations providing additional necessary information. AML with normal cytogenetics comprises about 40%-50% of all AML, and has been intensively investigated. The currently used 2008 World Health Organization classification of hematopoietic neoplasms has been proposed to be updated in2016, also to include an update on the classification of AML, due to the continuously increasing application of genomic techniques that have led to major advances in our knowledge of the pathogenesis of AML. The purpose of this review is to describe some of these recent major advances in the diagnostic classification and risk stratification of AML.展开更多
According to the structural characteristics of hazardous waste landfill and the leakage current model of high voltage DC Landfill leakage detection, a sealed model is established detail. The detection layer of the haz...According to the structural characteristics of hazardous waste landfill and the leakage current model of high voltage DC Landfill leakage detection, a sealed model is established detail. The detection layer of the hazardous waste landfill is considered as a sealed assumed that the source current flows through the leak entirely. The leak is regard and analyzed in space and it is ed as a positive current resource ＋ I located at the current entrance or a negative resource - I located at the current exit, which depends on the placement of the current supply. The electrical potential of an arbitrary in detection layer satisfies Poisson equation. The boundary condition is regarded as a natural bound- ary condition for the high resistivity of high density polyethylene （HDPE） membrane. Based on which a numerical calculation method is developed. Satisfactory agreement between experimental da- ta and simulated data validates the analysis. Parametric studies show that a larger horizontal distance between the power supply electrode and leak and a smaller distance between the detector electrodes and the detected liner are helpful to leak location. More parametric curves show that parameters leaks can be detected effectively with optimum selection of field survey.展开更多
文摘目的高-中危险度与低-极低危险度组胃间质瘤的影像诊断。方法回顾性分析2015年4月—2017年12月期间该院50例经手术病理证实的胃间质瘤患者的CT影像及病理资料,根据危险度不同,分为高-中危险组(24例)与低-极低危险组(26例),观察两组患者是否在CT特征上有差异。结果高-中级别组胃间质瘤钙化10例、坏死23例、形态(分叶)18例、最大径>4 cm 20例;低-极低级别组钙化3例、坏死10例、形态(分叶)7例、最大径>4 cm 8例,(P=0.035、0.000、0.001、0.001),高-中级别组溃疡13例、混合生长9例、年龄(56.95±14.22)岁、平扫CT值(31.95±8.57)、动脉期CT值(61.79±20.76)、门静脉期CT值(70.50±19.34);低-极低级别组溃疡11例、混合生长6例、年龄(55.50±11.11)、平扫CT值(34.69±7.44)、动脉期CT值(62.15±21.13)、门静脉期CT值(73.03±26.16),(P=0.402、0.266、0.687、0.237、0.952、0.700,χ~2=0.703,1.236,0.406,-1.199,-0.061,-0.387)。结论高-中危险度与低-极低危险度组胃间质瘤CT影像征象,对胃间质瘤危险度的分级具有重要的参考价值。
文摘Acute myeloid leukemia(AML) is a genetically heterogeneous myeloid malignancy that occurs more commonly in adults, and has an increasing incidence, most likely due to increasing age. Precise diagnostic classification of AML requires clinical and pathologic information, the latter including morphologic, immunophenotypic, cytogenetic and molecular genetic analysis. Risk stratification in AML requires cytogenetics evaluation as the most important predictor, with genetic mutations providing additional necessary information. AML with normal cytogenetics comprises about 40%-50% of all AML, and has been intensively investigated. The currently used 2008 World Health Organization classification of hematopoietic neoplasms has been proposed to be updated in2016, also to include an update on the classification of AML, due to the continuously increasing application of genomic techniques that have led to major advances in our knowledge of the pathogenesis of AML. The purpose of this review is to describe some of these recent major advances in the diagnostic classification and risk stratification of AML.
基金Supported by the National Basic Research Development Program of China(No.2010CB428506)the National High Technology Research and Development Program(No.2007AA061303)Beijing Higher Education Young Elite Teacher Project(YETP1756)
文摘According to the structural characteristics of hazardous waste landfill and the leakage current model of high voltage DC Landfill leakage detection, a sealed model is established detail. The detection layer of the hazardous waste landfill is considered as a sealed assumed that the source current flows through the leak entirely. The leak is regard and analyzed in space and it is ed as a positive current resource ＋ I located at the current entrance or a negative resource - I located at the current exit, which depends on the placement of the current supply. The electrical potential of an arbitrary in detection layer satisfies Poisson equation. The boundary condition is regarded as a natural bound- ary condition for the high resistivity of high density polyethylene （HDPE） membrane. Based on which a numerical calculation method is developed. Satisfactory agreement between experimental da- ta and simulated data validates the analysis. Parametric studies show that a larger horizontal distance between the power supply electrode and leak and a smaller distance between the detector electrodes and the detected liner are helpful to leak location. More parametric curves show that parameters leaks can be detected effectively with optimum selection of field survey.
