醒脑开窍针法配合高压氧对脑损伤昏迷患者促醒的临床疗效观察

目的:观察醒脑开窍针法配合高压氧对脑损伤昏迷患者促醒的临床疗效。方法:将70例颅脑损伤患者(GCS≤8)随机分为两组,治疗组36例和对照组34例,两组均给予营养神经、促醒、预防癫痫、抗感染等常规治疗,治疗组在此基础上加用醒脑开窍针法与高压氧治疗,1次/d,每10次为1个疗程。结果:治疗组和对照组治疗效果比较,差异有统计学意义(P<0.05)。结论:针灸配合高压氧治疗对颅脑外伤后昏迷患者有明显的促醒作用,应尽早进行。

YLC 0.5/1型婴儿高压氧舱洗舱法

目的：制订出合理的洗舱与稳压换氧方法，使稳压治疗期间舱内达到７５％以上的有效氧浓度。方法：测定加压前氧气洗舱后不同时间及加压后不同压力、稳压换氧后舱内氧浓度。结果：氧气洗舱１２ｍｉｎ后，不同压力稳压期间舱内氧浓度均在７５％以上。结论：本方法可使ＹＬＣ０．

持续氧雾化湿化法对昏迷气管切开患者的护理疗效观察

目的探讨持续高压氧气雾化湿化法在重型颅脑损伤、高血压脑出血行气管切开患者中的临床护理疗效。方法选择重型颅脑损伤、高血压脑出血行气管切开患者126例,随机分为治疗组和对照组,每组各63例,治疗组采用持续高压氧气雾化湿化法,对照组采用传统持续缓慢滴注湿化法,观察两组患者每天吸痰次数、排痰量及肺部感染和痰痂发生情况。结果治疗组患者每天排痰量、吸痰次数、肺部感染及痰痂发生率均较对照组低(P<0.05)。结论对重型颅脑损伤、高血压脑出血行气管切开患者采用持续氧雾化湿化法对降低呼吸道感染的发生率较持续滴注湿化法为优。

压力法回收金

金矿生产中的氰化物是激烈争论的环境论题。而皇后大学一教授已研制出用非氰化物浸出剂的高压浸出技术。他现正在试图证实它的经济可行性。难浸矿石的预处理有若干方法——焙烧、双氧化、压力氧化、生物淋滤。焙烧法在加拿大已使用了几十年,但仍存在一些缺点。焙烧产出含有硫、砷、锑和汞混合物的大量有害气体,而控制这些气体成本很高;金粒熔合在焙烧产物中,再清除已氧化的贱金属,增加了过程的费用。80年代末,试验通过了在酸性或高温条件下,对含有氯、氯化钠或次氯酸盐溶液的难浸矿石用高压氧化法萃取金的方案。这些过程很简单,且比其它方法更有效。

持续高压氧雾化湿化法在昏迷气管切开患者中的护理效果

目的探讨持续高压氧雾化湿化法应用于昏迷气管切开患者的护理效果。方法选择2014年11月～2016年11月该科收治的行气管切开术的重症昏迷患者84例，按人院编号分为对照组和观察组，各42例。单号纳人对照组，给予常规持续缓慢滴注湿化法；双号纳入观察组，给予持续高压氧雾化湿化法。两组均配合有效护理措施，对比分析两组湿化效果、每日吸痰次数、排痰量和并发症发生率。结果观察组湿化效果优于对照组，差异有统计学意义（P〈0．05）；观察组每日吸痰次数和排痰量均少于对照组，差异有统计学意义（均P〈0．05）；观察组气道黏膜损伤、痰痂形成、刺激性咳嗽、肺部感染发生率均低于对照组，差异有统计学意义（均P〈0．05）。结论持续高压氧雾化湿化法应用于昏迷气管切开患者效果显著，配合有效护理措施可改善湿化效果，减少每日吸痰次数和排痰量，降低并发症发生率，值得推广。

高压氧舱法检测咽鼓管通气功能在招飞体检中的应用

目的 验证高压氧舱法检测咽鼓管通气功能在招飞体检中应用的必要性和可行性。方法 对447名招飞体检初检合格者,用高压氧舱法检查咽鼓管通气功能。以10kPa/min速度增压,受检者咀嚼口香糖,做吞咽动作。增压至40 kPa时停留,医生用电耳镜观察受检者鼓膜,询问主观感觉。然后以10kPa/min速度减压至常压。按低压舱检测标准评定咽鼓管通气功能,Ⅱ、Ⅲ度者为功能不良。结果 受检者中15.4％被评定为咽鼓管通气功能不良,与未咀嚼口香糖组的不良率(35.4％)差异显著(X^2=15.32,P<0.01)。功能不良者都在增压2～3min内出现耳痛,未见鼓室积液、鼓膜破裂现象。减压后耳痛消失,鼓膜充血和内陷减轻。每次检查都在10min内完成。结论 招飞体检中用高压氧舱法检测咽鼓管通气功能是必要的和可行的。检查过程中受检者咀嚼口香糖可使评定结果更准确。

高压氧结合醒脑开窍针法治疗脑中风疗效观察

探究高压氧结合醒脑开窍针法运用在治疗脑中风患者的疗效观察。方法:从2019年12月—2020年12月开始,从本院选取脑中风患者100名作为本次研究的对象,这100名脑中风患者中男性58名,女性42名;年龄55周岁--78周岁,平均年龄58±13.2周岁。本次研究采用数字随机分组的方式及将这100名脑中风患者分为两组,分别为观察组与对照组,每组均为50人。对照组将采用常规治疗脑中风的方法,观察组采用高压氧结合醒脑开窍针法的方法。观察两组脑中风患者在不同治疗方法下的的满意度以及治疗效果。结果:观察组的患者经高压氧结合醒脑开窍针法治疗后效果明显,可较好的与他人交流,自理能力明显提高。观察患者的满意度明显高于对照组。结论:高压氧结合醒脑开窍针法治疗脑中风的方法可有效的改善患者在治疗时与治疗后的病情,该治疗方法的运用不仅减轻的患者的痛苦也减轻了病患家属的负担,可很好的在临床治疗中运用。

针灸治疗颈性眩晕概况

治疗颈性眩晕的方法很多,相对于西医的手术、物理疗法,中医的体针疗法,头针疗法,腹针疗法,电针疗法,火针疗法,钩活术针刺,针刺配合中药穴位敷贴,针刺配合药物服用,针灸配合推拿手法,针灸配合高压氧法,艾灸疗法,小针刀疗法,放血疗法,穴位注射法,耳穴疗法,推拿法,药物熏蒸等治疗方法则更安全有效。

Combination of allopurinol and hyperbaric oxygen therapy:A new treatment in experimental acute necrotizing pancreatitis?

瞄准：在试验性的老鼠在生物化学、组织病理学说的变化，氧化压力，和细菌的易位(BT ) 上调查 allopurinol 和高比重的氧(HBO ) 治疗的单个、联合的效果尖锐胰腺炎(AP ) 。方法：85 只 Sprague-Dawley 老鼠在学习被包括。85 只老鼠中的十五个被用作控制(假冒，组我) 。AP 在留下经由管内牛磺胆酸盐注入被导致七十只老鼠。幸存到尖锐引起坏死胰腺炎的正式就职的老鼠被使随机化进四个组。组 II 独自收到了 saline，组 III allopurinol，加 HBO 的组 IV allopurinol 和组 V HBO。浆液淀粉酶层次，氧化压力参数， BT 和组织病理学说的分数是坚定的。结果：浆液淀粉酶层次在与组 II 相比的组 III， IV 和 V 是更低的(974 +/- 110， 384 +/- 40， 851 +/- 56，和 1664 +/- 234 U/L，分别地 P 【 0.05，为所有) 。联合揭示的二种处理选择显著地降低 median [25-75 百分位数] 组织病理学说的分数什么时候与单个政府相比(13 [12.5-15 ] 在 allopurinol 组， 9.5 [7-11.75 ] 在 HBO 组，并且 6 [4.5-7.5 ] 在联合的组， P 【 0.01 ) 。氧化压力标记在与控制相比的所有处理组显著地更好。进胰和 mes 伤寒淋巴结的细菌的易位在与组 II 相比的组 III ， IV 和 V 是更低的(54%，23%，50%对为到胰的易位的100%，并且62%，46%，58%对为到 mes 伤寒淋巴节点的易位的100%，分别地 P 【 0.05 为所有)。结论：当在试验性的老鼠 AP 独立管理了时，现在的学习证实 HBO 和 allopurinol 处理的利益。这些处理选择的联合看起来更有效地阻止胰腺的损害参数的前进。

Neuroprotective effect of high-dose hyperbaric oxygenation on rats with acute cerebral infarction in super-early stage:Curative comparison between 9-hour and 18-hour therapeutic protocols

BACKGROUND:Previously,only single short-time low-dose hyperbaric oxygenation(HBO) protocol was administrated to treat acute ischemic stroke in early stage and the conflicting results were obtained. There are few studies to report the outcome of administering long-time(can cover all the natural pathologic progression period) high-dose HBO to treat the disease. OBJECTIVE:To evaluate the therapeutic effect between two kinds of high-dose hyperbaric oxygenation on super-early stage of acute permanent middle cerebral artery occlusion(MCAO) in rats. DESIGN:A randomized controlled experimental study. SETTING:Beijing Tiantan Hospital,Capital Medical University;Beijing Research Institute of Neurosurgery. MATERIALS:Seventy-four male SD rats,aged 2.5 months old,weighing(280±20)g,were provided by the Animal Institute,Chinese Academy of Medical Sciences. Hyperbaric oxygenation device was hyperbaric air cabin in which there was a self-made pure oxygen animal experimental cabin(made in China). METHODS:This experiment was carried out in the municipal laboratory of Beijing Tiantan Hospital affiliated to Capital Medical University and Beijing Research Institute of Neurosurgery. ① Experimental intervention:All the rats were developed into models of permanent MCAO by suture embolism. Then,they were randomly divided into two HBO groups(9 hours and 18 hours) and control group,with 24 rats in each as well as 3-hour ultrastructure control group,with 2 rats. After being modeled for 3 hours,rats in the two HBO groups stayed in the hyperbaric cabin for 9 hours and 18 hours,separately. Rats in the 9-hour HBO group inhaled pure oxygen at hours 1,3,5,7 and 9,and hyperbaric air at hours 2,4,6 and 8. Rats in the 18-hour HBO group inhaled pure oxygen at hours 1,3,5,7,9,11,13,15 and 17,and hyperbaric air at hours 2,4,6,8,10 12,14,16 and 18. After being created into models,rats in the control group and 3-hour ultrastructure control group breathed room air. ② Experimental evaluation:Neurologic functions of rat models in the 9-hour and 18-hour HBO groups as well as control group were scored by Bederson and Garica two neurological grading systems at hours 14 and 28 and on day 5;Infarct volume of rat models in the two HBO groups and control group was measured at hour 24 and on day 5 with NIH image processing software Image J;The pathological changes of brain tissue in the brain infarct region and its opposite region of rat models in the two HBO groups and 3-hour ultrastructure control group were observed with a Philips EM 208S transmission electron microscope. MAIN OUTCOME MEASURES:① Neurobehavioral outcome. ② Rat brain infarct volume. ③ Ultrastructure of brain tissue in the ischemic penumbra of infarct models at the different time points RESULTS:① Neurobehavioral outcome:After treatment,Garica score in the 9-hour and 18-hour HBO groups was significantly higher than that in the control group(P < 0.01). Bederson score on day 5 after modeling in the 9-hour and 18-hour HBO groups was significantly lower than that in the control group(P < 0.01). ② Cerebral infarct volume:Cerebral infarct volume in the 9-hour and 18-hour HBO groups was significantly smaller than that in the control group at hour 24 and on day 5 after modeling(P < 0.01). In the 18-hour HBO group,infarct volume on day 5 after modeling was significantly larger than that at hour 24 after modeling(P < 0.05). ③In the 3-hour ultrastructure control group,astrocyte edema and neuron damage around the capillary in the infarct cerebral tissue significantly relieved in the rats which were subjected to HBO. CONCLUSION:High dose of HBO is highly efficient in reducing infarct volume and improvingneurobehavioral outcome of rats with acute cerebral infarction,and also has an important role in inhibiting the pathological progression of ischemic brain tissue after cerebral infarction.

Hyperbaric oxygen therapy for promoting the intellectual rehabilitation of infants with severe hypoxic-ischemic encephalopathy A 5-year follow-up

BACKGROUND: It has been reported that early intervention of hyperbaric oxygen (HBO) can promote the intellectual rehabilitation of infants with severe hypoxic-ischemic encephalopathy (HIE) and can prevent mental retardation recently. However,the prior observations on the therapeutic effect almost were short-term. How about the observations on prospective efficacy and the following up on systematic intelligence test? OBJECTIVE: To investigate the short-term and long-term effects of HBO therapy on the promotion of the intellectual rehabilitation in infants with severe HIE. DESIGN: A comparative observation. SETTING: Department of Pediatrics,Affiliated Hospital,Qingdao University Medical College. PARTICIPANTS: Forty-seven infants with severe HIE (35 males and 12 females) were treated with HBO in the Department of Pediatrics,the Affiliated Hospital of the Medical College of Qingdao University from October 1996 to July 1999. All of them were consistent with the diagnostic criteria and clinical grading on severe HIE which were designed by Chinese Medical Association pediatrics committee neonate group in Hangzhou,October,1996. Informed contents were obtained from the relatives of all the infants. METHODS: ① Grouping: The infants were randomly divided into two groups according to the order of admission,those of odd numbers were HBO group (n =24) and those of even numbers were control group (n =23). All the infants were treated with routine therapy for 3 months,in addition to HBO therapy in the HBO group,once a day for 4 courses of 10 days with the interval of 10–15 days since 8 to 10 days after birth. HBO chamber produced by the 701 Institute of China Ship Industry Company was used,and the therapy pressure was 0.14–0.16 MPa,and the time of compression and decompression were both 15 minutes while voltage-stabilizing was 30 minutes. ② In order to evaluate the short-term and long-term effects of HBO on intellectual rehabilitation in infants with HIE,neonatal behavioral neurological assessment (NBNA) was employed at 7 and 28 days after birth,and Bayley scale of infant development (BSID) was got at two years old in both groups,as well as Wechsler preschool and primary scale of intelligence (WPPSI) at five years. MAIN OUTCOME MEASURES: Comparison of short-term and long-term intelligence between the two groups. RESULTS: ① Results of NBNA: The NBNA score at 28 days was significantly higher in the HBO group than in the control group (P < 0.01). ② Results of BSID: The score of mental development index (MDI) of BSID at two years old in the HBO group was significantly higher than that in the control group (P < 0.05). ③ Results of WPPSI: The score of full-scale intelligence quotient (FIQ) and verbal intelligence quotient (VIQ) of WPPSI in the HBO group were significantly higher than those in the control group (P < 0.05). In addition,the rate of mental retardation in the HBO group was significantly lower than that in the control group 12.5% (3/24),39.1%(9/23),P < 0.05. CONCLUSION: Not only the short-term intellectual rehabilitation but also the long-term one in infants with severe HIE could be promoted by HBO therapy,which might be benefit to the prevention of mental retardation.

Study of Treating HAPE with HBO in Situ at the Altitude of 4636m

Study Objective: To evaluate the treatment effect of HAPE with HBO in situ at an extreme altitude of 4636 m. To investigate the relationship between pulmonary hypertension (PH) and HAPE. To emphasize the importance of the treatment in situ.Methods: The 32 patients from the plateau of 4636～5130 m (the barometric pressure: 57.41～53.28 kPa/431.6～400.6 mmHg(1 mmHg=133.3224 Pa), the partial pressure of oxygen: 12.0～11.6 kPa/90.0～87.0 mmHg) were treated in situ of 4636 m altitude with HBO. Before and after the treatment, the clinical symptoms / signs, radiographic evidence, SaO2, and MPAP were compared.Results: The clinical symptoms/signs, and all the targets of the patients were improved dramatically (p<0.001).Conclusions: Treating HAPE with HBO is the most effective method among various therapies in situ at an extreme altitude. The pulmonary -artery pressure was significantly decreased. All cases showed improved immediately. Among the subjects, 11 cases (34.3%) were cured at once. The therapy made it possible for patients to get further treatment at a lower altitude area with prospective good results. We suggested that treating HAPE with HBO should be the first choice in situ. There must be PH in the patients of HAPE, but the reverse is not the true. The PH is a mechanism of normal compensation of the body exposing in the hypoxic environment. It is very necessary for us to explore the threshold of PH when a HAPE happens.