Several methods for investigating the thickness uniformity of polymer thin films are presented as well as their measurement principles. A comparison of these experimental methods is given.The cylindrical lightwave ref...Several methods for investigating the thickness uniformity of polymer thin films are presented as well as their measurement principles. A comparison of these experimental methods is given.The cylindrical lightwave reflection method is found to can obtain the thickness distribution along a certain direction.It is a simple and suitable method to evaluate the film thickness uniformity.展开更多
Simulation method is used to provide a guideline f or ultra thin body(UTB) MOSFET designs.Three important parameters of the UTB MOS FE T,i.e.the raised S/D height,Ge mole fraction of the Ge xSi 1-x gate,and the ...Simulation method is used to provide a guideline f or ultra thin body(UTB) MOSFET designs.Three important parameters of the UTB MOS FE T,i.e.the raised S/D height,Ge mole fraction of the Ge xSi 1-x gate,and the silic on body thickness,are comprehensively analyzed and optimized.The optimal region of feasible Ge mole fraction and the silicon body thickness for low operating po wer device are given.As the simulation results show that through changing Ge mole fraction coupl ed with the silicon body thickness tuning,UTB device with good performance can b e obtained.展开更多
Objective This study aimed to combine tumor abnormal protein(TAP) and high-sensitivity C-reactive protein(hs-CRP) level detection to diagnose endometrial cancer in patients with endometrial thickness less than 8 mm, a...Objective This study aimed to combine tumor abnormal protein(TAP) and high-sensitivity C-reactive protein(hs-CRP) level detection to diagnose endometrial cancer in patients with endometrial thickness less than 8 mm, and to provide a reference for clinical screening and diagnosis. Methods Clinical data from 19 cases of endometrial cancer, diagnosed on the basis of pathological findings, were collected from September 2014 to December 2015. The inclusion criteria were as follows: the patients were first diagnosed with endometrial thickness less than 8 mm and were all in menopause. Perimenopausal patients(n = 26) with uterine fibroids seen during the same period were selected as a control group. Serum TAP and hs-CRP levels of the patients in the two groups were simultaneously determined on admission. Results We found that both TAP and hs-CRP levels in the experimental group were higher than those in the control group [(182.95 ± 72.14) μm^2 vs.(133.19 ± 55.18) μm^2, P = 0.019;(7.52 ± 19.03) mg/L vs.(1.66 ± 2.31) mg/L, P = 0.136]. The sensitivity of TAP for the diagnosis of endometrial cancer was 73.68%, the specificity was 69.23%, and the Youden index was 0.4291. The diagnostic sensitivity and specificity of hs-CRP was 15.79% and 100%, respectively, and the Youden index was 0.1579. After plotting the receiver operating characteristics curves, the optimal cut-off value for TAP in diagnosing endometrial cancer was found to be 160.662 μm^2 and that for hs-CRP was 1.07 mg/L. Conclusion For patients suspected of having endometrial cancer with endometrial thickness less than 8 mm, combined detection of TAP and hs-CRP levels can be used as a screening tool and can provide new ideas regarding clinical diagnosis and treatment.展开更多
Objective: To assess the lower tear meniscus height(LTMH), central tear film thickness(CTFT), and central corneal epithelial thickness(CCET) after deep anterior lamellar keratoplasty(DALK). Methods: This was...Objective: To assess the lower tear meniscus height(LTMH), central tear film thickness(CTFT), and central corneal epithelial thickness(CCET) after deep anterior lamellar keratoplasty(DALK). Methods: This was a retrospective cross-sectional study of 20 patients who had DALK in one eye over a three-month period. LTMH, CTFT, and CCET of the operated eyes and the unoperated fellow eyes were measured using high-definition optical coherence tomography(HD-OCT). Correlations between three OCT assessments and age, time following surgery, graft size, bed size, and the number of residual sutures were analyzed. Results: Compared to patients with keratoconus, patients with other corneal conditions had significantly higher CCET in the fellow eye(P=0.024). For all patients, CCET in the operated eye was significantly negatively correlated with the number of residual sutures(R=-0.579, P=0.008), and was significantly positively correlated with time following surgery(R=0.636, P=0.003). In the fellow eye, a significant positive correlation was found between age and CCET(R=0.551, P=0.012), and a significant negative correlation between age and CTFT(R=-0.491, P=0.028). LTMH was found to be significantly correlated between operated and fellow eyes(R=0.554, P=0.011). There was no significant correlation between LTMH and age, bed/graft size, time following surgery, or residual sutures(all possible correlations, P0.05). Conclusions: Patients with keratoconus tend to have a thinner central corneal epithelium. Corneal epithelium keeps regenerating over time after DALK. DALK did not induce a significant change in tear volume compared with the fellow eye. Postoperative tear function might depend on an individual's general condition, rather than on age, gender, bed/graft size, time following surgery, or residual sutures.展开更多
A high-sensitivity metal-coated long-period fiber grating(LPFG) sensor based on material dispersion is designed.Based on the coupled mode theory,the influence of the material dispersion on the dual-peak characteristic...A high-sensitivity metal-coated long-period fiber grating(LPFG) sensor based on material dispersion is designed.Based on the coupled mode theory,the influence of the material dispersion on the dual-peak characteristics of the metal-coated LPFG is studied.After considering the material dispersion,the jumping region of the dual-resonant-wavelength shifts toward the thinner film thickness,and the sensitivity of the dual-peak metal-coated LPFG sensor to liquid refractive index(RI) can be obtained to supply accurate parameter combinations.Experimentally,two kinds of silver-coated LPFGs with different film thicknesses and grating periods are fabricated to monitor the salt solution,and the sensitivities of these two sensors are compared.The experimental results are consistent with the theoretical analyses.展开更多
文摘Several methods for investigating the thickness uniformity of polymer thin films are presented as well as their measurement principles. A comparison of these experimental methods is given.The cylindrical lightwave reflection method is found to can obtain the thickness distribution along a certain direction.It is a simple and suitable method to evaluate the film thickness uniformity.
文摘Simulation method is used to provide a guideline f or ultra thin body(UTB) MOSFET designs.Three important parameters of the UTB MOS FE T,i.e.the raised S/D height,Ge mole fraction of the Ge xSi 1-x gate,and the silic on body thickness,are comprehensively analyzed and optimized.The optimal region of feasible Ge mole fraction and the silicon body thickness for low operating po wer device are given.As the simulation results show that through changing Ge mole fraction coupl ed with the silicon body thickness tuning,UTB device with good performance can b e obtained.
基金Supported by a grant from the Medical and Health Technology Development Program in Shandong Province(No.2015WS0407)
文摘Objective This study aimed to combine tumor abnormal protein(TAP) and high-sensitivity C-reactive protein(hs-CRP) level detection to diagnose endometrial cancer in patients with endometrial thickness less than 8 mm, and to provide a reference for clinical screening and diagnosis. Methods Clinical data from 19 cases of endometrial cancer, diagnosed on the basis of pathological findings, were collected from September 2014 to December 2015. The inclusion criteria were as follows: the patients were first diagnosed with endometrial thickness less than 8 mm and were all in menopause. Perimenopausal patients(n = 26) with uterine fibroids seen during the same period were selected as a control group. Serum TAP and hs-CRP levels of the patients in the two groups were simultaneously determined on admission. Results We found that both TAP and hs-CRP levels in the experimental group were higher than those in the control group [(182.95 ± 72.14) μm^2 vs.(133.19 ± 55.18) μm^2, P = 0.019;(7.52 ± 19.03) mg/L vs.(1.66 ± 2.31) mg/L, P = 0.136]. The sensitivity of TAP for the diagnosis of endometrial cancer was 73.68%, the specificity was 69.23%, and the Youden index was 0.4291. The diagnostic sensitivity and specificity of hs-CRP was 15.79% and 100%, respectively, and the Youden index was 0.1579. After plotting the receiver operating characteristics curves, the optimal cut-off value for TAP in diagnosing endometrial cancer was found to be 160.662 μm^2 and that for hs-CRP was 1.07 mg/L. Conclusion For patients suspected of having endometrial cancer with endometrial thickness less than 8 mm, combined detection of TAP and hs-CRP levels can be used as a screening tool and can provide new ideas regarding clinical diagnosis and treatment.
基金Project supported by the Zhejiang Provincial Natural Science Foundation of China(No.LQ16H120002)
文摘Objective: To assess the lower tear meniscus height(LTMH), central tear film thickness(CTFT), and central corneal epithelial thickness(CCET) after deep anterior lamellar keratoplasty(DALK). Methods: This was a retrospective cross-sectional study of 20 patients who had DALK in one eye over a three-month period. LTMH, CTFT, and CCET of the operated eyes and the unoperated fellow eyes were measured using high-definition optical coherence tomography(HD-OCT). Correlations between three OCT assessments and age, time following surgery, graft size, bed size, and the number of residual sutures were analyzed. Results: Compared to patients with keratoconus, patients with other corneal conditions had significantly higher CCET in the fellow eye(P=0.024). For all patients, CCET in the operated eye was significantly negatively correlated with the number of residual sutures(R=-0.579, P=0.008), and was significantly positively correlated with time following surgery(R=0.636, P=0.003). In the fellow eye, a significant positive correlation was found between age and CCET(R=0.551, P=0.012), and a significant negative correlation between age and CTFT(R=-0.491, P=0.028). LTMH was found to be significantly correlated between operated and fellow eyes(R=0.554, P=0.011). There was no significant correlation between LTMH and age, bed/graft size, time following surgery, or residual sutures(all possible correlations, P0.05). Conclusions: Patients with keratoconus tend to have a thinner central corneal epithelium. Corneal epithelium keeps regenerating over time after DALK. DALK did not induce a significant change in tear volume compared with the fellow eye. Postoperative tear function might depend on an individual's general condition, rather than on age, gender, bed/graft size, time following surgery, or residual sutures.
基金supported by the National Natural Science Foundation of China(No.60777035)the Scientific Research Key Project Fund(No.208040)+1 种基金the Innovation Program of Shanghai Municipal Education Commission(No.11ZZ131)the Shanghai Leading Academic Discipline Project(No.S30502)
文摘A high-sensitivity metal-coated long-period fiber grating(LPFG) sensor based on material dispersion is designed.Based on the coupled mode theory,the influence of the material dispersion on the dual-peak characteristics of the metal-coated LPFG is studied.After considering the material dispersion,the jumping region of the dual-resonant-wavelength shifts toward the thinner film thickness,and the sensitivity of the dual-peak metal-coated LPFG sensor to liquid refractive index(RI) can be obtained to supply accurate parameter combinations.Experimentally,two kinds of silver-coated LPFGs with different film thicknesses and grating periods are fabricated to monitor the salt solution,and the sensitivities of these two sensors are compared.The experimental results are consistent with the theoretical analyses.