The most commonly found fingermarks at crime scenes are latent and, thus, an efficient method for detecting latent fingermarks is very important. However, traditional developing techniques have drawbacks such as low d...The most commonly found fingermarks at crime scenes are latent and, thus, an efficient method for detecting latent fingermarks is very important. However, traditional developing techniques have drawbacks such as low detection sensitivity, high background interference, complicated operation, and high toxicity. To tackle this challenge, we employed fluorescent NaYF4：Yb, Er upconversion nanoparticles （UCNPs）, which can fluoresce visible light when excited by 980 nm human-safe near-infrared light, to stain the latent fingermarks on various substrate surfaces. The UCNPs were successfully used as a novel fluorescent label for the detection of latent fingermarks with high sensitivity, low background, high efficiency, and low toxicity on various substrates including non-infiltrating materials （glass, marble, aluminum alloy sheets, stainless steel sheets, aluminum foils, and plastic cards）, semi-infiltrating materials （floor leathers, ceramic tiles, wood floor, and painted wood）, and infiltrating materials such as various types of papers. This work shows that UCNPs are a versatile fluorescent label for the facile detection of fingermarks on virtually any material, enabling their practical applications in forensic sciences.展开更多
A sulfonated 9,10-distyrylanthracene derivative with aggregation-induced emission (AIE) property is designed and synthesized. It shows a highly sensitive and selective fluorescence enhancement property for bovine seru...A sulfonated 9,10-distyrylanthracene derivative with aggregation-induced emission (AIE) property is designed and synthesized. It shows a highly sensitive and selective fluorescence enhancement property for bovine serum albumin (BSA) protein detection and quantification. Analysis on the interaction between the probe molecule and BSA reveals the essential role of the hydrophobic cavities of the protein folding structure.展开更多
A highly sensitive and selective two-photon sensing scheme for detection of cartap was developed by using Au@Ag bimetallic core-shell nanoparticles.Cartap was found to induce the aggregation of Au@Ag nanoparticles and...A highly sensitive and selective two-photon sensing scheme for detection of cartap was developed by using Au@Ag bimetallic core-shell nanoparticles.Cartap was found to induce the aggregation of Au@Ag nanoparticles and up to 700-fold enhancement in two-photon photoluminescence.Huge enhancement in two-photon photoluminescence allows achieving a detection limit of as low as 0.0062 mg/kg,which is better than the conventional colorimetric methods.This two-photon sensing scheme has a broad dynamic range and displays excellent selectivity in detection of cartap against over other ten kinds of commonly used insecticides.展开更多
Au nanoparticle（Au NP）@SiO2@TDA-Eu nanocomposites were prepared by a two-step process： Au NP@SiO2 nanocomposites were prepared by a modified onepot process. Then the europium coordination polymer was deposited on t...Au nanoparticle（Au NP）@SiO2@TDA-Eu nanocomposites were prepared by a two-step process： Au NP@SiO2 nanocomposites were prepared by a modified onepot process. Then the europium coordination polymer was deposited on the surface of the Au NP@SiO2 by mixing 2,2＇-thiodiacetic acid [S（CH2 COO）2^（2-）, TDA] and Eu（NO3）3·6 H2 O in ethanol via a hydrothermal method. The maximum fluorescent enhancement factor of the nanocomposites was 6.81 at 30 nm thickness of silica between the core of the Au NP and the shell of TDA-Eu. The prepared nanocomposites exhibit more sensitive monitoring of reactive oxygen species.展开更多
基金This work is supported by the National Natural Science Foundation of China （No. 21205139）, the Application and Innovation Project of Chinese Ministry of Public Security （No. 2012YYCXXJXY127）, and the Program for Liaoning Excellent Talents in University （No. LJQ2014130）. MYY is thankful for the grant support from the National Natural Science Foundation of China （Nos. 20804037 and 21172194） and National High Technology Research and Development Program 863 （No. 2013AA102507）. YZ, PHQ and CBM would like to thank the financial support from National Institutes of Health （No. EB015190）, National Natural Science Foundation （No. CMMI-1234957 and DMR-0847758）, Department of Defense Peer Reviewed Medical Research Program （No. W81XWH-12-1-0384）, Oklahoma Center for the Advancement of Science and Technology （No. HR14-160） and Oklahoma Center for Adult Stem Cell Research （No. 434003）.
文摘The most commonly found fingermarks at crime scenes are latent and, thus, an efficient method for detecting latent fingermarks is very important. However, traditional developing techniques have drawbacks such as low detection sensitivity, high background interference, complicated operation, and high toxicity. To tackle this challenge, we employed fluorescent NaYF4：Yb, Er upconversion nanoparticles （UCNPs）, which can fluoresce visible light when excited by 980 nm human-safe near-infrared light, to stain the latent fingermarks on various substrate surfaces. The UCNPs were successfully used as a novel fluorescent label for the detection of latent fingermarks with high sensitivity, low background, high efficiency, and low toxicity on various substrates including non-infiltrating materials （glass, marble, aluminum alloy sheets, stainless steel sheets, aluminum foils, and plastic cards）, semi-infiltrating materials （floor leathers, ceramic tiles, wood floor, and painted wood）, and infiltrating materials such as various types of papers. This work shows that UCNPs are a versatile fluorescent label for the facile detection of fingermarks on virtually any material, enabling their practical applications in forensic sciences.
基金the National Basic Research Pro- gram of China (973 Program, 2013CB834702, 2009CB623605)the Natural Science Foundation of China (21074045, 21204027, 21221063)+1 种基金the Research Fund for the Doctoral Program of Higher Education of China (20120061120016)the Project of Jilin Province (20100704)
文摘A sulfonated 9,10-distyrylanthracene derivative with aggregation-induced emission (AIE) property is designed and synthesized. It shows a highly sensitive and selective fluorescence enhancement property for bovine serum albumin (BSA) protein detection and quantification. Analysis on the interaction between the probe molecule and BSA reveals the essential role of the hydrophobic cavities of the protein folding structure.
基金the Ministry of Education, Singapore (R-143-000-607-112)the National Research Foundation, Prime Minister’s Office, Singapore under its Competitive Research Program (NRF-CRP10-2012-04)Medium Sized Centre Programme
文摘A highly sensitive and selective two-photon sensing scheme for detection of cartap was developed by using Au@Ag bimetallic core-shell nanoparticles.Cartap was found to induce the aggregation of Au@Ag nanoparticles and up to 700-fold enhancement in two-photon photoluminescence.Huge enhancement in two-photon photoluminescence allows achieving a detection limit of as low as 0.0062 mg/kg,which is better than the conventional colorimetric methods.This two-photon sensing scheme has a broad dynamic range and displays excellent selectivity in detection of cartap against over other ten kinds of commonly used insecticides.
基金financially supported by the National Natural Science Foundation of China (51702006 and 21501141)the Doctoral research project (ZK2017027) of Baoji University of Arts and Sciencesthe Education Commission of Shaanxi Province (2015JQ6223,12JS114,14JS092 and 17JS009)
文摘Au nanoparticle（Au NP）@SiO2@TDA-Eu nanocomposites were prepared by a two-step process： Au NP@SiO2 nanocomposites were prepared by a modified onepot process. Then the europium coordination polymer was deposited on the surface of the Au NP@SiO2 by mixing 2,2＇-thiodiacetic acid [S（CH2 COO）2^（2-）, TDA] and Eu（NO3）3·6 H2 O in ethanol via a hydrothermal method. The maximum fluorescent enhancement factor of the nanocomposites was 6.81 at 30 nm thickness of silica between the core of the Au NP and the shell of TDA-Eu. The prepared nanocomposites exhibit more sensitive monitoring of reactive oxygen species.
