MyosinV随机步长分布的动力学分析

MyosinV利用ATP水解所释放的自由能,朝肌动蛋白微丝正端作连续的定向运动,平均步长约为36nm。最近几年,诸多实验数据表明,myosinV步长并不固定为36nm,马达各步长值和相应步长出现概率的柱状图符合高斯分布;且在负载力大于2pN的情况下会出现“中间步长”和“后退步子”的现象。可根据已有实验数据,同时考虑马达在跃迁过程中所受的溶液摩擦阻力、常负载力和高斯随机力对其跃迁距离的影响,提出一种跃迁模型,并以此为基础对上述现象进行理论解释。

Simulation of Influence of Partially Coherent Gaussian Laser Beam on Gradient Force Acting on Dielectric Nanoparticle inside Random Medium

The partially coherent beams propagating through random media have been used in the past to enhance effect of nonlinear optical interaction. Moreover, after propagation through a random （or turbulent） medium the coherent beam becomes a partially coherent one. In this research, the analytical formula for the average intensity of Gaussian beam propagating through random medium is derived and the influence of coherent partiality on optical gradient force acting on dielectric particle rounded by a random media is investigated.