25年前Roscoe O Brady首次提出用酶替代方法治疗高歇病(Gaucher)以后进行了一系列实验,但都未能治愈。现Brady等提出了一种新的酶治疗方法,极大地缓解了这种使人衰弱甚至致死的疾病。高歇病患者继承了一种有缺陷的酶,不能分解脂肪物质...25年前Roscoe O Brady首次提出用酶替代方法治疗高歇病(Gaucher)以后进行了一系列实验,但都未能治愈。现Brady等提出了一种新的酶治疗方法,极大地缓解了这种使人衰弱甚至致死的疾病。高歇病患者继承了一种有缺陷的酶,不能分解脂肪物质葡糖脑苷脂。展开更多
Exercise training provides physiological benefits for both improving athletic performance and maintaining good health. Different exercise training modalities and strategies exist. Two common exercise strategies are hi...Exercise training provides physiological benefits for both improving athletic performance and maintaining good health. Different exercise training modalities and strategies exist. Two common exercise strategies are high-intensity interval training （HIIT） and moderate-intensity continuous exercise training （MCT）. HIIT was first used early in the 20th century and popularized later that century for improving performance of Olympic athletes. The primary premise underlying HIIT is that, compared to energy expenditure-matched MCT, a greater amount of work is performed at a higher intensity during a single exercise session which is achieved by alternating high-intensity exercise intervals with low-intensity exercise or rest intervals. Emerging research suggests that this same training method can provide beneficial effects for patients with a chronic disease and should be included in the comprehensive medical management plan. Accordingly, a major consideration in developing an individual exercise prescription for a patient with a chronic disease is the selection of an appropriate exercise strategy. In order to maximize exercise training benefits, this strategy should be tailored to the individual＇s need. The focus of this paper is to provide a brief summary of the current literature re^ardin~ the use of HIIT to enhance the fimctional capacity of individuals with cardiovascular, pulmonary, and diabetes diseases.展开更多
文摘Exercise training provides physiological benefits for both improving athletic performance and maintaining good health. Different exercise training modalities and strategies exist. Two common exercise strategies are high-intensity interval training （HIIT） and moderate-intensity continuous exercise training （MCT）. HIIT was first used early in the 20th century and popularized later that century for improving performance of Olympic athletes. The primary premise underlying HIIT is that, compared to energy expenditure-matched MCT, a greater amount of work is performed at a higher intensity during a single exercise session which is achieved by alternating high-intensity exercise intervals with low-intensity exercise or rest intervals. Emerging research suggests that this same training method can provide beneficial effects for patients with a chronic disease and should be included in the comprehensive medical management plan. Accordingly, a major consideration in developing an individual exercise prescription for a patient with a chronic disease is the selection of an appropriate exercise strategy. In order to maximize exercise training benefits, this strategy should be tailored to the individual＇s need. The focus of this paper is to provide a brief summary of the current literature re^ardin~ the use of HIIT to enhance the fimctional capacity of individuals with cardiovascular, pulmonary, and diabetes diseases.
